Aplastic anemia secondary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Nazia Fuad M.D.

Overview

Effective measures for the secondary prevention of complications of aplastic anemia include avoiding raw meats, dairy products, or fruits. These vegetables or fruits might be colonized by bacteria, fungus, or molds. Salt-limited diet is recommended during therapy with steroids or cyclosporin. These patients should avoid any activity that increases the risk of trauma during periods of thrombocytopenia. Menstruating women should recieve hormonal pills to avoid menstrual cycles that might get heavy due to thrombocytopenia. Patients should be informed of the increased risk of community-acquired infections during periods of neutropenia and lymphopenia, and they should maintain hygiene to reduce the risks of infection.

Secondary Prevention

Effective measures for the secondary prevention of complications of aplastic anemia include[1]

  • Diet care: Patients with aplastic anemia who have neutropenia or who are receiving immunosuppressive therapy should not consume raw meats, dairy products, or fruits.
    • These vegetables or fruits might be colonized by bacteria, fungus, or molds.
    • Salt-limited diet is recommended during therapy with steroids or cyclosporine.
    • These patients should avoid any activity that increases the risk of trauma during periods of thrombocytopenia.
    • Menstruating women should recieve hormonal pills to avoid menstrual cycles that might get heavy due to thrombocytopenia.
    • Patients should be informed of the increased risk of community-acquired infections during periods of neutropenia and lymphopenia.
    • Patients should maintain hygiene to reduce the risks of infection.

References

  1. Marsh JC, Ball SE, Cavenagh J, Darbyshire P, Dokal I, Gordon-Smith EC, Keidan J, Laurie A, Martin A, Mercieca J, Killick SB, Stewart R, Yin JA (October 2009). "Guidelines for the diagnosis and management of aplastic anaemia". Br. J. Haematol. 147 (1): 43–70. doi:10.1111/j.1365-2141.2009.07842.x. PMID 19673883.