Aortic dissection laboratory findings: Difference between revisions

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==Biomarker Studies==
==Biomarker Studies==
*There has been one report using a smooth muscle [[myosin heavy chain]] immunoassay to help diagnose aortic dissection.  They report that a level > 10 ng/ml within the first 12h is 90% sensitive and 97% specific.  This finding needs to be confirmed in other trials however.
*There has been one report using a smooth muscle [[myosin]] heavy chain immunoassay to help diagnose aortic dissection.  They report that a level > 10 ng/ml within the first 12h is 90% sensitive and 97% specific.  This finding needs to be confirmed in other trials however.
*The presence of an elevated [[CK MB]] may indicate the presence of concomitant [[acute myocardial infarction]] (often a [[right coronary artery]] occlusion due to occlusion of the ostium of the [[RCA]] by the dissection).
*The presence of an elevated [[CK MB]] may indicate the presence of concomitant [[acute myocardial infarction]] (often a [[right coronary artery]] occlusion due to occlusion of the ostium of the [[RCA]] by the dissection).



Revision as of 01:45, 29 October 2012

Aortic dissection Microchapters

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Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Aortic dissection from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Special Scenarios

Management during Pregnancy

Case Studies

Case #1


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Overview

Routine blood work is usually not helpful and should not delay definitive diagnostic studies such as a CT scan and treatment.

Complete Blood Count

Hemolysis can be present as a result of blood in the false lumen.

Biomarker Studies

  • There has been one report using a smooth muscle myosin heavy chain immunoassay to help diagnose aortic dissection. They report that a level > 10 ng/ml within the first 12h is 90% sensitive and 97% specific. This finding needs to be confirmed in other trials however.
  • The presence of an elevated CK MB may indicate the presence of concomitant acute myocardial infarction (often a right coronary artery occlusion due to occlusion of the ostium of the RCA by the dissection).

Urinalysis

References

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