Anti-NMDA receptor encephalitis laboratory findings: Difference between revisions

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==Laboratory Findings==
==Laboratory Findings==
CSF Findings
CSF white blood cells are frequently elevated in fewer than 200/mm3, and pleocytosis is commonly observed. Protein concentration is either normal or modestly elevated, and 60% of patients have CSF-specific oligoclonal bands. Immunoglobulin G (IgG) index and oligoclonal band tests are clinically relevant since they can be aberrant in normal CSF cell counts and protein levels.
CSF white blood cells are frequently elevated in fewer than 200/mm3, and pleocytosis is commonly observed. Protein concentration is either normal or modestly elevated, and 60% of patients have CSF-specific oligoclonal bands. Immunoglobulin G (IgG) index and oligoclonal band tests are clinically relevant since they can be aberrant in normal CSF cell counts and protein levels.



Revision as of 13:44, 13 May 2023

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] AE Dheeraj Makkar, M.D.[2]

Overview

In Anti-NMDA encephalitis, cerebrospinal fluid (CSF) analysis often shows mildly elevated white blood cell count, modestly increased protein levels, and the presence of oligoclonal bands. CSF-specific tests like IgG index and oligoclonal band tests can provide diagnostic value.

Laboratory Findings

CSF Findings CSF white blood cells are frequently elevated in fewer than 200/mm3, and pleocytosis is commonly observed. Protein concentration is either normal or modestly elevated, and 60% of patients have CSF-specific oligoclonal bands. Immunoglobulin G (IgG) index and oligoclonal band tests are clinically relevant since they can be aberrant in normal CSF cell counts and protein levels.

References

[1] [2] Template:WH Template:WS

  1. Dalmau J, Gleichman AJ, Hughes EG, Rossi JE, Peng X, Lai M; et al. (2008). "Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies". Lancet Neurol. 7 (12): 1091–8. doi:10.1016/S1474-4422(08)70224-2. PMC 2607118. PMID 18851928.
  2. Titulaer MJ, McCracken L, Gabilondo I, Iizuka T, Kawachi I, Bataller L; et al. (2013). "Late-onset anti-NMDA receptor encephalitis". Neurology. 81 (12): 1058–63. doi:10.1212/WNL.0b013e3182a4a49c. PMC 3795591. PMID 23946310.