Anti-NMDA receptor encephalitis laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
In Anti-NMDA encephalitis, cerebrospinal fluid (CSF) analysis often shows mildly elevated white blood cell count, modestly increased protein levels, and the presence of oligoclonal bands. CSF-specific tests like IgG index and oligoclonal band tests can provide diagnostic value. | |||
==Laboratory Findings== | ==Laboratory Findings== | ||
CSF white blood cells are frequently elevated in fewer than 200/mm3, and pleocytosis is commonly observed. Protein concentration is either normal or modestly elevated, and 60% of patients have CSF-specific oligoclonal bands. Immunoglobulin G (IgG) index and oligoclonal band tests are clinically relevant since they can be aberrant in normal CSF cell counts and protein levels. | CSF Findings | ||
*CSF white blood cells are frequently elevated in fewer than 200/mm3, and pleocytosis is commonly observed. | |||
*Protein concentration is either normal or modestly elevated, and 60% of patients have CSF-specific oligoclonal bands. | |||
*Immunoglobulin G (IgG) index and oligoclonal band tests are clinically relevant since they can be aberrant in normal CSF cell counts and protein levels. | |||
==References== | ==References== | ||
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[[Category:Rheumatology]] | [[Category:Rheumatology]] | ||
[[Category:Disease]] | [[Category:Disease]] | ||
<ref name="pmid18851928">{{cite journal| author=Dalmau J, Gleichman AJ, Hughes EG, Rossi JE, Peng X, Lai M | display-authors=etal| title=Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies. | journal=Lancet Neurol | year= 2008 | volume= 7 | issue= 12 | pages= 1091-8 | pmid=18851928 | doi=10.1016/S1474-4422(08)70224-2 | pmc=2607118 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18851928 }} </ref> | |||
<ref name="pmid23946310">{{cite journal| author=Titulaer MJ, McCracken L, Gabilondo I, Iizuka T, Kawachi I, Bataller L | display-authors=etal| title=Late-onset anti-NMDA receptor encephalitis. | journal=Neurology | year= 2013 | volume= 81 | issue= 12 | pages= 1058-63 | pmid=23946310 | doi=10.1212/WNL.0b013e3182a4a49c | pmc=3795591 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23946310 }} </ref> | |||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Latest revision as of 13:44, 13 May 2023
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Anti-NMDA receptor encephalitis Microchapters |
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Differentiating Anti-NMDA receptor encephalitis from Other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] AE Dheeraj Makkar, M.D.[2]
Overview
In Anti-NMDA encephalitis, cerebrospinal fluid (CSF) analysis often shows mildly elevated white blood cell count, modestly increased protein levels, and the presence of oligoclonal bands. CSF-specific tests like IgG index and oligoclonal band tests can provide diagnostic value.
Laboratory Findings
CSF Findings
- CSF white blood cells are frequently elevated in fewer than 200/mm3, and pleocytosis is commonly observed.
- Protein concentration is either normal or modestly elevated, and 60% of patients have CSF-specific oligoclonal bands.
- Immunoglobulin G (IgG) index and oligoclonal band tests are clinically relevant since they can be aberrant in normal CSF cell counts and protein levels.
References
[1] [2] Template:WH Template:WS
- ↑ Dalmau J, Gleichman AJ, Hughes EG, Rossi JE, Peng X, Lai M; et al. (2008). "Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies". Lancet Neurol. 7 (12): 1091–8. doi:10.1016/S1474-4422(08)70224-2. PMC 2607118. PMID 18851928.
- ↑ Titulaer MJ, McCracken L, Gabilondo I, Iizuka T, Kawachi I, Bataller L; et al. (2013). "Late-onset anti-NMDA receptor encephalitis". Neurology. 81 (12): 1058–63. doi:10.1212/WNL.0b013e3182a4a49c. PMC 3795591. PMID 23946310.