Ankylosing spondylitis MRI: Difference between revisions

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{{Ankylosing spondylitis}}
{{Ankylosing spondylitis}}
{{CMG}}
{{CMG}} ; {{AE}} {{VKG}}


==Overview==
==Overview==
The findings on MRI in a patient with ankylosing spondylitis is synovial enhancement. It is superior to CT in detection of cartilage, bone erosions, and [[subchondral]] bone changes. An increased T2 signal correlates with edema or vascularized fibrous tissue.
[[Magnetic resonance imaging|MRI]] may be helpful in the diagnosis of [[ankylosing spondylitis]]. Findings on [[MRI]] suggestive of [[ankylosing spondylitis]] include [[sacroiliitis]], disease activity,[[cartilage]] condition and [[enthesitis]].MRI allows assessment of all of the structures that are involved in [[musculoskeletal]] diseases.MRI is more sensitive in [[inflammatory]] and [[degenerative]] rheumatological disorders.However, not all patients with nr-axSpA have abnormal MRI findings.


==MRI==
==MRI Scan==
* May have a role in early diagnosis of sacroiliitis
* Findings on [[Magnetic resonance imaging|MRI]] suggestive of [[ankylosing spondylitis]] include:<ref name="LacoutRousselin2008">{{cite journal|last1=Lacout|first1=Alexis|last2=Rousselin|first2=Benoît|last3=Pelage|first3=Jean-Pierre|title=CT and MRI of Spine and Sacroiliac Involvement in Spondyloarthropathy|journal=American Journal of Roentgenology|volume=191|issue=4|year=2008|pages=1016–1023|issn=0361-803X|doi=10.2214/AJR.07.3446}}</ref><ref name="pmid22859929">{{cite journal |vauthors=Ostergaard M, Lambert RG |title=Imaging in ankylosing spondylitis |journal=Ther Adv Musculoskelet Dis |volume=4 |issue=4 |pages=301–11 |date=August 2012 |pmid=22859929 |pmc=3403247 |doi=10.1177/1759720X11436240 |url=}}</ref><ref name="pmid11242208">{{cite journal |vauthors=Shih TT, Chen PQ, Li YW, Hsu CY |title=Spinal fractures and pseudoarthrosis complicating ankylosing spondylitis: MRI manifestation and clinical significance |journal=J Comput Assist Tomogr |volume=25 |issue=2 |pages=164–70 |date=2001 |pmid=11242208 |doi= |url=}}</ref><ref name="pmid19019894">{{cite journal |vauthors=Marzo-Ortega H, McGonagle D, O'Connor P, Hensor EM, Bennett AN, Green MJ, Emery P |title=Baseline and 1-year magnetic resonance imaging of the sacroiliac joint and lumbar spine in very early inflammatory back pain. Relationship between symptoms, HLA-B27 and disease extent and persistence |journal=Ann. Rheum. Dis. |volume=68 |issue=11 |pages=1721–7 |date=November 2009 |pmid=19019894 |doi=10.1136/ard.2008.097931 |url=}}</ref><ref name="pmid20496416">{{cite journal |vauthors=Weber U, Lambert RG, Østergaard M, Hodler J, Pedersen SJ, Maksymowych WP |title=The diagnostic utility of magnetic resonance imaging in spondylarthritis: an international multicenter evaluation of one hundred eighty-seven subjects |journal=Arthritis Rheum. |volume=62 |issue=10 |pages=3048–58 |date=October 2010 |pmid=20496416 |doi=10.1002/art.27571 |url=}}</ref><ref name="pmid19454404">{{cite journal |vauthors=Rudwaleit M, Jurik AG, Hermann KG, Landewé R, van der Heijde D, Baraliakos X, Marzo-Ortega H, Ostergaard M, Braun J, Sieper J |title=Defining active sacroiliitis on magnetic resonance imaging (MRI) for classification of axial spondyloarthritis: a consensual approach by the ASAS/OMERACT MRI group |journal=Ann. Rheum. Dis. |volume=68 |issue=10 |pages=1520–7 |date=October 2009 |pmid=19454404 |doi=10.1136/ard.2009.110767 |url=}}</ref><ref name="pmid26768408">{{cite journal |vauthors=Lambert RG, Bakker PA, van der Heijde D, Weber U, Rudwaleit M, Hermann KG, Sieper J, Baraliakos X, Bennett A, Braun J, Burgos-Vargas R, Dougados M, Pedersen SJ, Jurik AG, Maksymowych WP, Marzo-Ortega H, Østergaard M, Poddubnyy D, Reijnierse M, van den Bosch F, van der Horst-Bruinsma I, Landewé R |title=Defining active sacroiliitis on MRI for classification of axial spondyloarthritis: update by the ASAS MRI working group |journal=Ann. Rheum. Dis. |volume=75 |issue=11 |pages=1958–1963 |date=November 2016 |pmid=26768408 |doi=10.1136/annrheumdis-2015-208642 |url=}}</ref>
* Synovial enhancement on MR correlates with disease activity measured by inflammatory mediators
** Helps in diagnosis of active [[sacroiliitis]]
* Superior to CT in detection of cartilage, bone erosions, and [[subchondral]] bone changes
** Helps in diagnosis of [[enthesitis]]/ [[capsulitis]]
* Increased T2 signal correlates with edema or vascularized fibrous tissue
** Helps in detection of bone marrow edema (BME)
* Useful in following treatment results in patients with active ankylosing spondylitis
** Helps in detection of fat [[metaplasia]]
(Images courtesy of RadsWiki)
** Helps in detection of:
<gallery>
*** [[Cartilage]] [[inflammation]] and destruction
Image:AS-dural-ectasia-001.jpg|AS with [[dural ectasia]]
*** Bone erosions
Image:AS-dural-ectasia-002.jpg|AS with [[dural ectasia]]
*** Subchondral [[bone]] changes
</gallery>
[[File:Ankylosing-spondylitis-16.jpg|center|thumb|Bilateral '''sacroiliitis'''
 "<nowiki>https://radiopaedia.org/</nowiki>">Radiopaedia.org<nowiki></a></nowiki>. From the case <nowiki><a href="https://radiopaedia.org/cases/22345">rID: 22345</a></nowiki>
]]


<gallery>
Image:Ankylosing-spondylitis-002.jpg|Bamboo Spine
</gallery>
<gallery>
Image:Ankylosing-spondylitis-301.jpg|Symmetrical sacroiliac joint fusion
Image:Ankylosing-spondylitis-302.jpg|Symmetrical sacroiliac joint fusion
</gallery>
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Latest revision as of 21:40, 15 April 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]

Overview

MRI may be helpful in the diagnosis of ankylosing spondylitis. Findings on MRI suggestive of ankylosing spondylitis include sacroiliitis, disease activity,cartilage condition and enthesitis.MRI allows assessment of all of the structures that are involved in musculoskeletal diseases.MRI is more sensitive in inflammatory and degenerative rheumatological disorders.However, not all patients with nr-axSpA have abnormal MRI findings.

MRI Scan

Bilateral sacroiliitis  "https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/22345">rID: 22345</a>

References

  1. Lacout, Alexis; Rousselin, Benoît; Pelage, Jean-Pierre (2008). "CT and MRI of Spine and Sacroiliac Involvement in Spondyloarthropathy". American Journal of Roentgenology. 191 (4): 1016–1023. doi:10.2214/AJR.07.3446. ISSN 0361-803X.
  2. Ostergaard M, Lambert RG (August 2012). "Imaging in ankylosing spondylitis". Ther Adv Musculoskelet Dis. 4 (4): 301–11. doi:10.1177/1759720X11436240. PMC 3403247. PMID 22859929.
  3. Shih TT, Chen PQ, Li YW, Hsu CY (2001). "Spinal fractures and pseudoarthrosis complicating ankylosing spondylitis: MRI manifestation and clinical significance". J Comput Assist Tomogr. 25 (2): 164–70. PMID 11242208.
  4. Marzo-Ortega H, McGonagle D, O'Connor P, Hensor EM, Bennett AN, Green MJ, Emery P (November 2009). "Baseline and 1-year magnetic resonance imaging of the sacroiliac joint and lumbar spine in very early inflammatory back pain. Relationship between symptoms, HLA-B27 and disease extent and persistence". Ann. Rheum. Dis. 68 (11): 1721–7. doi:10.1136/ard.2008.097931. PMID 19019894.
  5. Weber U, Lambert RG, Østergaard M, Hodler J, Pedersen SJ, Maksymowych WP (October 2010). "The diagnostic utility of magnetic resonance imaging in spondylarthritis: an international multicenter evaluation of one hundred eighty-seven subjects". Arthritis Rheum. 62 (10): 3048–58. doi:10.1002/art.27571. PMID 20496416.
  6. Rudwaleit M, Jurik AG, Hermann KG, Landewé R, van der Heijde D, Baraliakos X, Marzo-Ortega H, Ostergaard M, Braun J, Sieper J (October 2009). "Defining active sacroiliitis on magnetic resonance imaging (MRI) for classification of axial spondyloarthritis: a consensual approach by the ASAS/OMERACT MRI group". Ann. Rheum. Dis. 68 (10): 1520–7. doi:10.1136/ard.2009.110767. PMID 19454404.
  7. Lambert RG, Bakker PA, van der Heijde D, Weber U, Rudwaleit M, Hermann KG, Sieper J, Baraliakos X, Bennett A, Braun J, Burgos-Vargas R, Dougados M, Pedersen SJ, Jurik AG, Maksymowych WP, Marzo-Ortega H, Østergaard M, Poddubnyy D, Reijnierse M, van den Bosch F, van der Horst-Bruinsma I, Landewé R (November 2016). "Defining active sacroiliitis on MRI for classification of axial spondyloarthritis: update by the ASAS MRI working group". Ann. Rheum. Dis. 75 (11): 1958–1963. doi:10.1136/annrheumdis-2015-208642. PMID 26768408.

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