Addison's disease overview: Difference between revisions
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The condition is generally diagnosed with [[blood test]]s, [[medical imaging]] and additional investigations.<ref name=Ten/> Treatment is with replacement of the hormones (oral [[hydrocortisone]] and [[fludrocortisone]]). If the disease is caused by an underlying problem, this is addressed. Regular follow-up and monitoring for other health problems is necessary.<ref name=Ten/> | The condition is generally diagnosed with [[blood test]]s, [[medical imaging]] and additional investigations.<ref name=Ten/> Treatment is with replacement of the hormones (oral [[hydrocortisone]] and [[fludrocortisone]]). If the disease is caused by an underlying problem, this is addressed. Regular follow-up and monitoring for other health problems is necessary.<ref name=Ten/> | ||
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==Historical Perspective== | ==Historical Perspective== | ||
The condition is named after Dr. [[Thomas Addison]], the British [[physician]] who first described the condition in his 1855 ''On the Constitutional and Local Effects of Disease of the Suprarenal Capsules''.<ref>{{cite book | author = Thomas Addison | authorlink = Thomas Addison | title = On The Constitutional And Local Effects Of Disease Of The Supra-Renal Capsules | origyear = 1855 | url = http://www.wehner.org/addison/x1.htm | format = HTML reprint | publisher = Samuel Highley | location = London}}</ref> The adjective "Addisonian" is used for features of the condition, as well as for patients with Addison's disease.<ref name=Ten>{{cite journal |author=Ten S, New M, Maclaren N |title=Clinical review 130: Addison's disease 2001 |journal=J. Clin. Endocrinol. Metab. |volume=86 |issue=7 |pages=2909-22 |year=2001 |pmid=11443143 |url=http://jcem.endojournals.org/cgi/content/full/86/7/2909}}</ref> | The condition is named after Dr. [[Thomas Addison]], the British [[physician]] who first described the condition in his 1855 ''On the Constitutional and Local Effects of Disease of the Suprarenal Capsules''.<ref>{{cite book | author = Thomas Addison | authorlink = Thomas Addison | title = On The Constitutional And Local Effects Of Disease Of The Supra-Renal Capsules | origyear = 1855 | url = http://www.wehner.org/addison/x1.htm | format = HTML reprint | publisher = Samuel Highley | location = London}}</ref> The adjective "Addisonian" is used for features of the condition, as well as for patients with Addison's disease.<ref name=Ten>{{cite journal |author=Ten S, New M, Maclaren N |title=Clinical review 130: Addison's disease 2001 |journal=J. Clin. Endocrinol. Metab. |volume=86 |issue=7 |pages=2909-22 |year=2001 |pmid=11443143 |url=http://jcem.endojournals.org/cgi/content/full/86/7/2909}}</ref> | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Addison's disease is a rare endocrine disorder in which the adrenal gland produces insufficient amounts of steroid hormones (glucocorticoids and often mineralocorticoids). It may develop in children as well as adults, and may occur as the result of a large number of underlying causes. [1]
The condition is named after Dr Thomas Addison, the British physician who first described the condition in his 1855 On the Constitutional and Local Effects of Disease of the Suprarenal Capsules.[2] The adjective "Addisonian" is used for features of the condition, as well as patients with Addison's disease.[3]
The condition is generally diagnosed with blood tests, medical imaging and additional investigations.[3] Treatment is with replacement of the hormones (oral hydrocortisone and fludrocortisone). If the disease is caused by an underlying problem, this is addressed. Regular follow-up and monitoring for other health problems is necessary.[3] {{#ev:youtube|V6XcBp8EV7Q}}
Historical Perspective
The condition is named after Dr. Thomas Addison, the British physician who first described the condition in his 1855 On the Constitutional and Local Effects of Disease of the Suprarenal Capsules.[4] The adjective "Addisonian" is used for features of the condition, as well as for patients with Addison's disease.[3]
Diagnosis
Ultrasound
Abdominal ultrasound is typically normal in Addison's disease except for the small size of adrenal glands.
Treatment
Surgery
Surgeries may require significant adjustments to medication regimens prior to, during, and following any surgical procedure. The best preparation for any surgery, regardless of how minor or routine it may be, is to speak to one's primary care physician about the procedure and medication implications well in advance of the surgery.
References
- ↑ NIH Publication No. 04–3054: Addison's disease. A work by Endocrine and Metabolic Diseases Information Service. National Institute for Health. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 2004 June
- ↑ Thomas Addison. On The Constitutional And Local Effects Of Disease Of The Supra-Renal Capsules (HTML reprint). London: Samuel Highley.
- ↑ 3.0 3.1 3.2 3.3 Ten S, New M, Maclaren N (2001). "Clinical review 130: Addison's disease 2001". J. Clin. Endocrinol. Metab. 86 (7): 2909–22. PMID 11443143.
- ↑ Thomas Addison. On The Constitutional And Local Effects Of Disease Of The Supra-Renal Capsules (HTML reprint). London: Samuel Highley.