Acute respiratory distress syndrome risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Brian Shaller, M.D. [2]

Overview

Major risk factors that predispose to ARDS include advanced advanced age and cigarette smoke exposure. One of the most substantial risk factors for the development of ARDS is chronic alcoholism. Acute illnesses or infections, traumatic injuries, Adverse drug reactions, toxic exposures, and other acute precipitants of ARDS are discussed in the subchapter on causes of ARDS.

Risk Factors

Common risk factors for the development of ARDS are:


The association between chronic alcoholism and a higher risk of developing ARDS has been demonstrated in several research studies.[2][3] In one study, patients with a history of alcohol abuse were roughly twice as likely to develop ARDS and experienced a mortality rate that was 36% higher than age-, sex-, and disease-matched patients without a history of alcohol abuse.[2]

References

  1. Mangialardi RJ, Martin GS, Bernard GR, Wheeler AP, Christman BW, Dupont WD; et al. (2000). "Hypoproteinemia predicts acute respiratory distress syndrome development, weight gain, and death in patients with sepsis. Ibuprofen in Sepsis Study Group". Crit Care Med. 28 (9): 3137–45. PMID 11008971.
  2. 2.0 2.1 Moss M, Bucher B, Moore FA, Moore EE, Parsons PE (1996). "The role of chronic alcohol abuse in the development of acute respiratory distress syndrome in adults". JAMA. 275 (1): 50–4. PMID 8531287.
  3. Moss M, Burnham EL (2003). "Chronic alcohol abuse, acute respiratory distress syndrome, and multiple organ dysfunction". Crit Care Med. 31 (4 Suppl): S207–12. doi:10.1097/01.CCM.0000057845.77458.25. PMID 12682442.


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