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{{Acute respiratory distress syndrome}}
{{Acute respiratory distress syndrome}}
{{CMG}}
{{CMG}}, {{AE}} {{BShaller}}


==Overview==
==Overview==
Acute respiratory distress syndrome is relatively uncommon, occurring in 1.5-13.5 people per 100,000. It can be associated with a number of trigger conditions such as [[sepsis]], [[pulmonary aspiration|aspiration]], and [[pneumonia]].
The incidence of ARDS in the United States is estimated at around 75 cases per 100,000 person-years, which amounts to roughly 150,000 new cases per year.<ref name="pmid3410685">{{cite journal| author=Lucas AC| title=The future of radiological instrumentation. | journal=Health Phys | year= 1988 | volume= 55 | issue= 2 | pages= 191-5 | pmid=3410685 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3410685  }} </ref> There is substantial variance in the rates of ARDS between different countries and geographic regions due to factors such as mean life expectancy, prevalence of different [[risk factors]] and [[comorbidities]], and access to health care.


==Epidemiology and Demographics==
===Age===
* The annual incidence of ARDS is between 1.5 to 13.5 people per 100,000 in the general population
ARDS may affect people of all ages, however, it occurs more commonly in the [[elderly]].
* Its incidence in the [[intensive care unit]] (ICU), [[mechanical ventilation|mechanically ventilated]] population is much higher. Brun-Buisson ''et al.'' (2004) reported a prevalence of acute lung injury (ALI) (see below) of 16.1% percent in ventilated patients admitted for more than 4 hours. More than half these patients may develop ARDS.  
 
* Mortality varies from 30% to 60%. Usually, [[randomized controlled trials]] in the literature show lower death rates, both in control and treatment patients. This is thought to be due to stricter enrollment criteria. Observational studies generally report 50%-60% mortality.
===Gender===
Some studies have suggested that women are slightly more likely than men to develop ARDS, however, the [[mortality rate]] may be slightly higher among men than women.<ref name="pmid12163776">{{cite journal| author=Moss M, Mannino DM| title=Race and gender differences in acute respiratory distress syndrome deaths in the United States: an analysis of multiple-cause mortality data (1979- 1996). | journal=Crit Care Med | year= 2002 | volume= 30 | issue= 8 | pages= 1679-85 | pmid=12163776 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12163776  }} </ref><sup>,</sup><ref name="pmid21986736">{{cite journal| author=Heffernan DS, Dossett LA, Lightfoot MA, Fremont RD, Ware LB, Sawyer RG et al.| title=Gender and acute respiratory distress syndrome in critically injured adults: a prospective study. | journal=J Trauma | year= 2011 | volume= 71 | issue= 4 | pages= 878-83; discussion 883-5 | pmid=21986736 | doi=10.1097/TA.0b013e31822c0d31 | pmc=3201740 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21986736  }} </ref>
 
===Race===
*ARDS does not appear to disproportionately affect any particular racial group, however, in the United States the mortality rate among African Americans with ARDS is higher than among whites<ref name="pmid12163776">{{cite journal| author=Moss M, Mannino DM| title=Race and gender differences in acute respiratory distress syndrome deaths in the United States: an analysis of multiple-cause mortality data (1979- 1996). | journal=Crit Care Med | year= 2002 | volume= 30 | issue= 8 | pages= 1679-85 | pmid=12163776 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12163776  }} </ref>


==References==
==References==

Revision as of 11:05, 25 June 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Brian Shaller, M.D. [2]

Overview

The incidence of ARDS in the United States is estimated at around 75 cases per 100,000 person-years, which amounts to roughly 150,000 new cases per year.[1] There is substantial variance in the rates of ARDS between different countries and geographic regions due to factors such as mean life expectancy, prevalence of different risk factors and comorbidities, and access to health care.

Age

ARDS may affect people of all ages, however, it occurs more commonly in the elderly.

Gender

Some studies have suggested that women are slightly more likely than men to develop ARDS, however, the mortality rate may be slightly higher among men than women.[2],[3]

Race

  • ARDS does not appear to disproportionately affect any particular racial group, however, in the United States the mortality rate among African Americans with ARDS is higher than among whites[2]

References

  1. Lucas AC (1988). "The future of radiological instrumentation". Health Phys. 55 (2): 191–5. PMID 3410685.
  2. 2.0 2.1 Moss M, Mannino DM (2002). "Race and gender differences in acute respiratory distress syndrome deaths in the United States: an analysis of multiple-cause mortality data (1979- 1996)". Crit Care Med. 30 (8): 1679–85. PMID 12163776.
  3. Heffernan DS, Dossett LA, Lightfoot MA, Fremont RD, Ware LB, Sawyer RG; et al. (2011). "Gender and acute respiratory distress syndrome in critically injured adults: a prospective study". J Trauma. 71 (4): 878–83, discussion 883-5. doi:10.1097/TA.0b013e31822c0d31. PMC 3201740. PMID 21986736.


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