Acute chest syndrome laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Laboratory Findings

Electrolyte and Biomarker Studies

• Patients also commonly have a mild anemia and leukocytosis.
• Severe hypoxemia with a PaO2 <60mmHg can be seen in 20%.
• Bacteremia has been documented in up to 3.5% of patients.

  • The incidence decreases with age, and only 1.8% of patients older than 10, have positive blood cultures.
  • In the older group, S. pneumo has been isolated in roughly 25%, with other common organisms including H. influenza, S. aureus, Salmonella, Enterobacter, and Clostridia. Bacteremia in adults tends to be more common in patients with Hb SS disease.

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