Actinomycosis history and symptoms: Difference between revisions

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{{Actinomycosis}}
{{Actinomycosis}}
{{CMG}}
{{CMG}}


==Overview==
==Overview==
Consider actinomycosis when the patient has chronic progression of disease across tissue planes that is mass-like at times, sinus tract development that may heal and recur, and refractory infection after a typical course of antibiotics.
Actinomycosis can present with diverse clinical presentation, which include systemic flu-like symptoms and symptoms due to focal involvement of organs by the [[bacteria]].
 
==Symptoms ==
Symptoms of actinomycosis include :<ref name="pmid27311002">{{cite journal |vauthors=Bonnefond S, Catroux M, Melenotte C, Karkowski L, Rolland L, Trouillier S, Raffray L |title=Clinical features of actinomycosis: A retrospective, multicenter study of 28 cases of miscellaneous presentations |journal=Medicine (Baltimore) |volume=95 |issue=24 |pages=e3923 |year=2016 |pmid=27311002 |pmc=4998488 |doi=10.1097/MD.0000000000003923 |url=}}</ref><ref name="pmid21738348">{{cite journal |vauthors=Sung HY, Lee IS, Kim SI, Jung SE, Kim SW, Kim SY, Chung MK, Kim WC, Oh ST, Kang WK |title=Clinical features of abdominal actinomycosis: a 15-year experience of a single institute |journal=J. Korean Med. Sci. |volume=26 |issue=7 |pages=932–7 |year=2011 |pmid=21738348 |pmc=3124725 |doi=10.3346/jkms.2011.26.7.932 |url=}}</ref><ref name="pmid19718405">{{cite journal |vauthors=Choi MM, Baek JH, Beak JH, Lee JN, Park S, Lee WS |title=Clinical features of abdominopelvic actinomycosis: report of twenty cases and literature review |journal=Yonsei Med. J. |volume=50 |issue=4 |pages=555–9 |year=2009 |pmid=19718405 |pmc=2730619 |doi=10.3349/ymj.2009.50.4.555 |url=}}</ref><ref name="pmid3317731">{{cite journal| author=Smego RA| title=Actinomycosis of the central nervous system. | journal=Rev Infect Dis | year= 1987 | volume= 9 | issue= 5 | pages= 855-65 | pmid=3317731 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3317731  }} </ref><ref name="pmid27630971">{{cite journal |vauthors=Meethal AC, Pattamparambath M, Balan A, Kumar NR, Sathyabhama S |title=Actinomycotic Osteomyelitis of the Maxilla - A Delusive Presentation |journal=J Clin Diagn Res |volume=10 |issue=7 |pages=ZJ01–3 |year=2016 |pmid=27630971 |pmc=5020198 |doi=10.7860/JCDR/2016/19171.8086 |url=}}</ref><ref name="pmid25280832">{{cite journal |vauthors=Shikino K, Ikusaka M, Takada T |title=Cervicofacial actinomycosis |journal=J Gen Intern Med |volume=30 |issue=2 |pages=263 |year=2015 |pmid=25280832 |pmc=4314475 |doi=10.1007/s11606-014-3001-z |url=}}</ref><ref name="pmid28202870">{{cite journal |vauthors=Higashi Y, Nakamura S, Ashizawa N, Oshima K, Tanaka A, Miyazaki T, Izumikawa K, Yanagihara K, Yamamoto Y, Miyazaki Y, Mukae H, Kohno S |title=Pulmonary Actinomycosis Mimicking Pulmonary Aspergilloma and a Brief Review of the Literature |journal=Intern. Med. |volume=56 |issue=4 |pages=449–453 |year=2017 |pmid=28202870 |doi=10.2169/internalmedicine.56.7620 |url=}}</ref>
{| class="wikitable"
!Type
!History
!Symptoms
|-
|'''[[Cervicofacial actinomycosis]]'''
|
* Poor [[oral]] hygiene or dental caries
* Periodontal [[disease]]
* [[Osteonecrosis]] (due to bisphosphonates or radiation therapy)
|
*Tender swollen lumps on [[cheeks]] or [[neck]] during initial stages and later become hard and painless.
*[[Fever]]
*Difficulty chewing due to [[stiffness]] of [[jaw]]
*[[Sinus]] tracts on the [[Lump|lumps]] which drain yellow granular material
*Reddish or bluish discoloration of [[skin]] over the lump
|-
|'''[[Thoracic actinomycosis]]'''
|History of [[aspiration]] ([[seizure]] disorder, [[alcoholism]], and poor [[dental hygiene]])
|
*[[Fever]]
*[[Fatigue]]
*[[Weight loss]]
*[[Loss of appetite]]
*[[Chest pain]]
*[[Shortness of breath]]
*Sinus tracts which drain yellow granular material
|-
|'''Abdominal actinomycosis'''
|
* [[Abdominal surgery]]
* Perforated [[viscus]], [[mesenteric vascular insufficiency]], or ingestion of foreign bodies
|
*[[Fever]]
*[[Fatigue]]
*Change in [[bowel]] habits ([[constipation]] or [[diarrhea]])
*[[Abdominal pain]]
*[[Nausea and vomiting]]
*[[Mass]] or [[lump]] in the [[abdomen]]
*Sinus tracts which drain yellow granular material
|-
|'''Pelvic actinomycosis'''
|IUD (intrauterine device)
|
*Mild [[fever]]
*[[Lower abdominal pain]]
*[[Fatigue]]
*[[Loss of appetite]]
*Mass or lump in the pelvis
|-
|'''[[Central nervous system actinomycosis|CNS actinomycosis]]'''
|[[Trauma]]
|
* [[Headache]]
* [[Nausea and vomiting]]
* [[Dizziness]]
* [[Seizures]]
* [[Fever]]
|}


== Symptoms == 
* Cervicofacial Actinomycosis (55%)
*:* Acute painful [[pyogenic]] [[abscess]] or indolent angle-of-jaw mass
* Thoracic Actinomycosis
*:* [[Lungs]]
*:* [[Pleura]]
*:* [[Mediastinum]]
*:* Chest wall ([[aspiration]], extension of cervicofacial disease, transdiaphragmatic or retroperitoneal spread)
*:*:* Clinical picture of  [[tuberculosis]] (TB) or [[malignancy]]
* [[Abdominal]] and [[Pelvic]] Actinomycosis
*:* Following:
*:*:* Penetrating [[trauma]]
*:*:* [[Gut perforation]]
*:*:* [[Surgical]] manipulation
*:* [[Ileocecal]] predilection
*:*:* Confused with:
*:*:*:* [[TB]]
*:*:*:* Ameboma
*:*:*:* Chronic appy
*:*:*:* [[Regional enteritis]]
*:*:*:* [[Carcinoma]]
*:*:*:* [[Intrauterine devices]] (IUD’s)
* [[Central Nervous System]] (CNS)
*:* [[Brain abscess]]
*:* [[Meningitis]]
*:* [[Meningoencephalitis]]
*:* [[Subdural empyema]]
==References==
==References==
{{reflist|2}}
{{reflist|2}}
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[[Category:Bacterial diseases]]
[[Category:Bacterial diseases]]
[[Category:Disease]]
[[Category:Disease]]
[[Category:Infectious disease]]
 
[[Category:Overview complete]]
[[Category:Overview complete]]
[[Category:Dermatology]]
[[Category:Dermatology]]

Latest revision as of 16:18, 18 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Actinomycosis can present with diverse clinical presentation, which include systemic flu-like symptoms and symptoms due to focal involvement of organs by the bacteria.

Symptoms

Symptoms of actinomycosis include :[1][2][3][4][5][6][7]

Type History Symptoms
Cervicofacial actinomycosis
  • Tender swollen lumps on cheeks or neck during initial stages and later become hard and painless.
  • Fever
  • Difficulty chewing due to stiffness of jaw
  • Sinus tracts on the lumps which drain yellow granular material
  • Reddish or bluish discoloration of skin over the lump
Thoracic actinomycosis History of aspiration (seizure disorder, alcoholism, and poor dental hygiene)
Abdominal actinomycosis
Pelvic actinomycosis IUD (intrauterine device)
CNS actinomycosis Trauma

References

  1. ↑ Bonnefond S, Catroux M, Melenotte C, Karkowski L, Rolland L, Trouillier S, Raffray L (2016). "Clinical features of actinomycosis: A retrospective, multicenter study of 28 cases of miscellaneous presentations". Medicine (Baltimore). 95 (24): e3923. doi:10.1097/MD.0000000000003923. PMC 4998488. PMID 27311002.
  2. ↑ Sung HY, Lee IS, Kim SI, Jung SE, Kim SW, Kim SY, Chung MK, Kim WC, Oh ST, Kang WK (2011). "Clinical features of abdominal actinomycosis: a 15-year experience of a single institute". J. Korean Med. Sci. 26 (7): 932–7. doi:10.3346/jkms.2011.26.7.932. PMC 3124725. PMID 21738348.
  3. ↑ Choi MM, Baek JH, Beak JH, Lee JN, Park S, Lee WS (2009). "Clinical features of abdominopelvic actinomycosis: report of twenty cases and literature review". Yonsei Med. J. 50 (4): 555–9. doi:10.3349/ymj.2009.50.4.555. PMC 2730619. PMID 19718405.
  4. ↑ Smego RA (1987). "Actinomycosis of the central nervous system". Rev Infect Dis. 9 (5): 855–65. PMID 3317731.
  5. ↑ Meethal AC, Pattamparambath M, Balan A, Kumar NR, Sathyabhama S (2016). "Actinomycotic Osteomyelitis of the Maxilla - A Delusive Presentation". J Clin Diagn Res. 10 (7): ZJ01–3. doi:10.7860/JCDR/2016/19171.8086. PMC 5020198. PMID 27630971.
  6. ↑ Shikino K, Ikusaka M, Takada T (2015). "Cervicofacial actinomycosis". J Gen Intern Med. 30 (2): 263. doi:10.1007/s11606-014-3001-z. PMC 4314475. PMID 25280832.
  7. ↑ Higashi Y, Nakamura S, Ashizawa N, Oshima K, Tanaka A, Miyazaki T, Izumikawa K, Yanagihara K, Yamamoto Y, Miyazaki Y, Mukae H, Kohno S (2017). "Pulmonary Actinomycosis Mimicking Pulmonary Aspergilloma and a Brief Review of the Literature". Intern. Med. 56 (4): 449–453. doi:10.2169/internalmedicine.56.7620. PMID 28202870.

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