Acromegaly history and symptoms: Difference between revisions

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{{Acromegaly}}
{{Acromegaly}}
{{CMG}}
{{CMG}}; {{AE}} {{AEL}}
==Symptoms==
Features that result from high level of hGH or expanding tumor include:
* Soft tissue swelling of the hands and feet
* Brow and lower jaw protrusion
* Enlarging hands
* Enlarging feet
* [[Arthritis]] and [[carpal tunnel syndrome]]
* Teeth spacing increase
* [[Macroglossia]] [enlarged tongue]
* [[Heart failure]]
* [[Kidney failure]]
* Compression of the [[optic chiasm]] leading to loss of vision in the outer visual fields (typically [[bitemporal hemianopia]])
* [[Headache]]
* [[Diabetes mellitus]]
* [[Hypertension]]
* Enlarging heart
* Increased palmar sweating and [[sebum]] production over the face ([[seborrhea]]) are clinical indicators of active growth hormone (GH) producing pituitary tumours. These symptoms can also be used to monitor the activity of the tumour after surgery although biochemical monitoring is confirmatory.
==References==


{{reflist|2}}
==Overview==
Common symptoms of acromegaly include enlarged hands and feet, [[headache]], increase sweating, [[sexual dysfunction]], [[skin]] thickening, deepening of the voice and, an [[Macroglossia|enlarged tongue]].  Less common symptoms of acromegaly include visual defects and irregular menses in the women.
==History and Symptoms==
===History===
Patients with acromegaly may have a positive history of:
*Rapid onset of acromegaly symptoms development
*Increase in shoe size due to enlarged [[feet]]
*Increase in ring size due to enlarged [[hand]]
===Common Symptoms===
Common symptoms of acromegaly include:<ref name="pmid1521514">{{cite journal| author=Molitch ME| title=Clinical manifestations of acromegaly. | journal=Endocrinol Metab Clin North Am | year= 1992 | volume= 21 | issue= 3 | pages= 597-614 | pmid=1521514 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1521514  }} </ref><ref name="pmid19884662">{{cite journal| author=Melmed S| title=Acromegaly pathogenesis and treatment. | journal=J Clin Invest | year= 2009 | volume= 119 | issue= 11 | pages= 3189-202 | pmid=19884662 | doi=10.1172/JCI39375 | pmc=2769196 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19884662  }} </ref>
*Enlarged hands and feet
*Change in the facial features
*[[Headache]]
*Increase [[sweating]]
*[[Paraesthesia]]
*[[Sexual dysfunction]]
*[[Skin]] thickening
*Protrusion of the lower [[mandible]]
*Deepening of voice
*[[Macroglossia|Enlarged tongue]]


[[Category:neuroendocrinology]]
===Less Common Symptoms===
[[Category:Growth disorders]]
Less common symptoms of acromegaly include:
[[Category:Growth hormones]]
*Visual defects
[[Category:Endocrinology]]
*In women, irregular menses


[[bg:Акромегалия]]
==References==
[[cs:Akromegalie]]
{{reflist|2}}
[[de:Akromegalie]]
[[es:Acromegalia]]
[[fr:Acromégalie]]
[[gl:Acromegalia]]
[[it:Acromegalia]]
[[he:אקרומגליה]]
[[nl:Acromegalie]]
[[ja:先端巨大症]]
[[no:Akromegali]]
[[pl:Akromegalia]]
[[pt:Acromegalia]]
[[sq:Akromegalia]]
[[sk:Akromegália]]
[[sr:Акромегалија]]
[[fi:Akromegalia]]
[[sv:Akromegali]]
[[tr:Akromegali]]
[[uk:Акромегалія]]
[[zh:肢端肥大症]]


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Latest revision as of 21:54, 24 August 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

Common symptoms of acromegaly include enlarged hands and feet, headache, increase sweating, sexual dysfunction, skin thickening, deepening of the voice and, an enlarged tongue. Less common symptoms of acromegaly include visual defects and irregular menses in the women.

History and Symptoms

History

Patients with acromegaly may have a positive history of:

  • Rapid onset of acromegaly symptoms development
  • Increase in shoe size due to enlarged feet
  • Increase in ring size due to enlarged hand

Common Symptoms

Common symptoms of acromegaly include:[1][2]

Less Common Symptoms

Less common symptoms of acromegaly include:

  • Visual defects
  • In women, irregular menses

References

  1. Molitch ME (1992). "Clinical manifestations of acromegaly". Endocrinol Metab Clin North Am. 21 (3): 597–614. PMID 1521514.
  2. Melmed S (2009). "Acromegaly pathogenesis and treatment". J Clin Invest. 119 (11): 3189–202. doi:10.1172/JCI39375. PMC 2769196. PMID 19884662.


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