Acoustic neuroma natural history, complications & prognosis: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Acoustic neuroma}} | {{Acoustic neuroma}} | ||
{{CMG}}{{AE}}{{Simrat}} | {{CMG}}{{AE}}{{Simrat}}{{Sab}} | ||
==Overview== | ==Overview== | ||
Approximately 50% of all acoustic neuromas grow slowly (1 - 2 mm/year). The growth rate is more rapid (greater than 2 mm/year) in about 20% of the [[Patient|patients]]. The [[tumor]] does not [[Metastasis|metastasize]] to other parts of the [[Human body|body]]. [[Hearing impairment|Hearing loss]], when occurs, is irreversible. If left untreated, an acoustic neuroma can block the flow of [[cerebrospinal fluid]] and cause [[hydrocephalus]], which may lead to severe [[Visual system|vision]] problems and difficulty [[breathing]] and [[swallowing]]. [[Complication (medicine)|Complications]] of acoustic neuroma include [[Hearing impairment|hearing loss]], [[Hydrocephalus]], and recurrence of the [[tumor]]. Small, slow-growing [[Tumor|tumors]] may not need treatment. [[Patient|Patients]] experience similar [[quality of life]] whether treatment is [[observation]], [[radiation]], or [[surgery]]. | |||
==Natural History | ==Natural History, Complications, and Prognosis== | ||
== | === Natural History === | ||
* | * Approximately 50% of all acoustic neuromas grow slowly (1 - 2 mm/year). The growth rate is more rapid (greater than 2 mm/year) in about 20% of the [[Patient|patients]]. | ||
* | * In more than 30% of the [[Patient|patients]], acoustic neuromas exhibit no growth at all. | ||
* | * The [[tumor]] does not [[Metastasis|metastasize]] to other parts of the [[Human body|body]]. | ||
*People with small, slow-growing tumors may not need treatment.<ref>{{Cite web | title =NIH acoustic neuroma Prognosis| url =https://www.nlm.nih.gov/medlineplus/ency/article/000778.htm }}</ref> | * As the [[tumor]] grows, it can start pressing on the surrounding [[brain]] tissue. | ||
* | * [[Hearing impairment|Hearing loss]], when occurs, is irreversible. | ||
* If treated, acoustic neuroma [[Patient|patients]] have a very good [[prognosis]] with minimal [[Complication (medicine)|complications]]. | |||
*A control rate of greater than 90% is found in tumors treated with focused [[radiation]]. | * People with small, slow-growing [[Tumor|tumors]] may not need treatment. | ||
* If left untreated, an acoustic neuroma can block the flow of [[cerebrospinal fluid]] and cause [[hydrocephalus]], which may lead to severe [[Visual system|vision]] problems and difficulty [[breathing]] and [[swallowing]].<ref>{{Cite journal | |||
| author = [[S. I. Rosenberg]] | |||
| title = Natural history of acoustic neuromas | |||
| journal = [[The Laryngoscope]] | |||
| volume = 110 | |||
| issue = 4 | |||
| pages = 497–508 | |||
| year = 2000 | |||
| month = April | |||
| doi = 10.1097/00005537-200004000-00002 | |||
| pmid = 10763994 | |||
}}</ref><ref>{{Cite journal | |||
| author = [[B. Strasnick]], [[M. E. 3rd Glasscock]], [[D. Haynes]], [[S. O. McMenomey]] & [[L. B. Minor]] | |||
| title = The natural history of untreated acoustic neuromas | |||
| journal = [[The Laryngoscope]] | |||
| volume = 104 | |||
| issue = 9 | |||
| pages = 1115–1119 | |||
| year = 1994 | |||
| month = September | |||
| doi = 10.1288/00005537-199409000-00011 | |||
| pmid = 8072358 | |||
}}</ref><ref>{{Cite journal | |||
<nowiki> </nowiki><nowiki>|</nowiki> author = [[Sven-Eric Stangerup]], [[Per Caye-Thomasen]], [[Mirko Tos]] & [[Jens Thomsen]] | |||
| title = The natural history of vestibular schwannoma | |||
| journal = [[Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology]] | |||
<nowiki> </nowiki><nowiki>|</nowiki> volume = 27 | |||
<nowiki> </nowiki><nowiki>|</nowiki> issue = 4 | |||
<nowiki> </nowiki><nowiki>|</nowiki> pages = 547–552 | |||
<nowiki> </nowiki><nowiki>|</nowiki> year = 2006 | |||
<nowiki> </nowiki><nowiki>|</nowiki> month = June | |||
<nowiki> </nowiki><nowiki>|</nowiki> doi = 10.1097/01.mao.0000217356.73463.e7 | |||
<nowiki> </nowiki><nowiki>|</nowiki> pmid = 16791048 | |||
}}</ref><ref name="NHS">Acoustic neuroma. NHS(2014) http://www.nhs.uk/Conditions/Acoustic-neuroma/Pages/Complications.aspx Accessed on October 2 2015</ref> | |||
===Complications=== | |||
[[Complication (medicine)|Complications]] of acoustic neuroma include:<ref name="NHS">Acoustic neuroma. NHS(2014) http://www.nhs.uk/Conditions/Acoustic-neuroma/Pages/Complications.aspx Accessed on October 2 2015</ref> | |||
*[[Hearing impairment|Hearing loss]] | |||
*[[Hydrocephalus]] | |||
*Recurrence of [[tumor]] | |||
===Prognosis=== | |||
*Small, slow-growing [[Tumor|tumors]] may not need treatment.<ref>{{Cite web | title =NIH acoustic neuroma Prognosis| url =https://www.nlm.nih.gov/medlineplus/ency/article/000778.htm }}</ref> | |||
*If treated, acoustic neuroma [[Patient|patients]] have a very good [[prognosis]] with minimal [[Complication (medicine)|complications]]. | |||
*A control rate of greater than 90% is found in [[Tumor|tumors]] treated with focused [[radiation]]. | |||
*A recurrence rate of less than 5% has been found following [[surgery]]. | *A recurrence rate of less than 5% has been found following [[surgery]]. | ||
*Patients experience | *[[Patient|Patients]] experience similar [[quality of life]] whether treatment is [[observation]], [[radiation]], or [[surgery]]. | ||
*Due to improved [[Surgery|surgical techniques]] and early [[diagnosis]], the [[morbidity]] associated with [[surgery]] is reduced.<ref name="pmid8072358">{{cite journal| author=Strasnick B, Glasscock ME, Haynes D, McMenomey SO, Minor LB| title=The natural history of untreated acoustic neuromas. | journal=Laryngoscope | year= 1994 | volume= 104 | issue= 9 | pages= 1115-9 | pmid=8072358 | doi=10.1288/00005537-199409000-00011 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8072358 }} </ref> | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
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{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Otolaryngology]] | |||
[[Category:Neurology]] | |||
[[Category:Neurosurgery]] | |||
Latest revision as of 20:03, 24 April 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]Sabawoon Mirwais, M.B.B.S, M.D.[3]
Overview
Approximately 50% of all acoustic neuromas grow slowly (1 - 2 mm/year). The growth rate is more rapid (greater than 2 mm/year) in about 20% of the patients. The tumor does not metastasize to other parts of the body. Hearing loss, when occurs, is irreversible. If left untreated, an acoustic neuroma can block the flow of cerebrospinal fluid and cause hydrocephalus, which may lead to severe vision problems and difficulty breathing and swallowing. Complications of acoustic neuroma include hearing loss, Hydrocephalus, and recurrence of the tumor. Small, slow-growing tumors may not need treatment. Patients experience similar quality of life whether treatment is observation, radiation, or surgery.
Natural History, Complications, and Prognosis
Natural History
- Approximately 50% of all acoustic neuromas grow slowly (1 - 2 mm/year). The growth rate is more rapid (greater than 2 mm/year) in about 20% of the patients.
- In more than 30% of the patients, acoustic neuromas exhibit no growth at all.
- The tumor does not metastasize to other parts of the body.
- As the tumor grows, it can start pressing on the surrounding brain tissue.
- Hearing loss, when occurs, is irreversible.
- If treated, acoustic neuroma patients have a very good prognosis with minimal complications.
- People with small, slow-growing tumors may not need treatment.
- If left untreated, an acoustic neuroma can block the flow of cerebrospinal fluid and cause hydrocephalus, which may lead to severe vision problems and difficulty breathing and swallowing.[1][2][3][4]
Complications
Complications of acoustic neuroma include:[4]
- Hearing loss
- Hydrocephalus
- Recurrence of tumor
Prognosis
- Small, slow-growing tumors may not need treatment.[5]
- If treated, acoustic neuroma patients have a very good prognosis with minimal complications.
- A control rate of greater than 90% is found in tumors treated with focused radiation.
- A recurrence rate of less than 5% has been found following surgery.
- Patients experience similar quality of life whether treatment is observation, radiation, or surgery.
- Due to improved surgical techniques and early diagnosis, the morbidity associated with surgery is reduced.[6]
References
- ↑ S. I. Rosenberg (2000). "Natural history of acoustic neuromas". The Laryngoscope. 110 (4): 497–508. doi:10.1097/00005537-200004000-00002. PMID 10763994. Unknown parameter
|month=ignored (help) - ↑ B. Strasnick, M. E. 3rd Glasscock, D. Haynes, S. O. McMenomey & L. B. Minor (1994). "The natural history of untreated acoustic neuromas". The Laryngoscope. 104 (9): 1115–1119. doi:10.1288/00005537-199409000-00011. PMID 8072358. Unknown parameter
|month=ignored (help) - ↑ {{Cite journal | author = Sven-Eric Stangerup, Per Caye-Thomasen, Mirko Tos & Jens Thomsen | title = The natural history of vestibular schwannoma | journal = [[Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology]] | volume = 27 | issue = 4 | pages = 547–552 | year = 2006 | month = June | doi = 10.1097/01.mao.0000217356.73463.e7 | pmid = 16791048 }}
- ↑ 4.0 4.1 Acoustic neuroma. NHS(2014) http://www.nhs.uk/Conditions/Acoustic-neuroma/Pages/Complications.aspx Accessed on October 2 2015
- ↑ "NIH acoustic neuroma Prognosis".
- ↑ Strasnick B, Glasscock ME, Haynes D, McMenomey SO, Minor LB (1994). "The natural history of untreated acoustic neuromas". Laryngoscope. 104 (9): 1115–9. doi:10.1288/00005537-199409000-00011. PMID 8072358.