Abdominal pain causes: Difference between revisions

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*[[Christmas Cherry poisoning|Christmas cherry poisoning]]
*[[Christmas Cherry poisoning|Christmas cherry poisoning]]
*[[Chromium ]]
*[[Chromium ]]
*Chromosome 1p deletion syndrome  
*[[1p36 deletion syndrome|Chromosome 1p deletion syndrome]]
*Chromosome 9q deletion syndrome  
*[['''9q34 deletion syndrome''', also known as '''Kleefstra syndrome''', is a rare [[genetic disorder]]. Terminal deletions of [[chromosome]] 9q34 have been associated with childhood [[hypotonia]], a distinctive facial appearance and [[developmental disability]]. The facial features typically described include arched eyebrows, small head circumference, midface [[hypoplasia]], prominent jaw and a pouting lower lip. Individuals with this disease may often have speech impediments, such as speech delays. Other characteristics of this disease include: [[epilepsy]], congenital and urogenetic defects, [[microcephaly]], corpulence, and psychiatric disorders.<ref>Berry Kravis, E.M., et al., Update on Kleefstra Syndrome. Molecular Syndromology. 2012 Jan;2:202-211.</ref> From analysis of chromosomal breakpoints, as well as gene sequencing in suggestive cases, Kleefstra and colleagues identified [[Histone methyltransferase|EHMT1]] as the causative gene.<ref>Kleefstra et al., Disruption of the gene Euchromatin Histone Methyl Transferase1 (Eu-HMTase1) is associated with the 9q34 subtelomeric deletion syndrome. J Med Genet. 2005 Apr;42(4):299-306.</ref> This gene is responsible for producing the protein Histone methyltransferase which functions to alter histones. Ultimately, histone methyltransferases are important in deactivating certain genes, needed for proper growth and development. Moreover, a frameshift, missense, or nonsense error in the coding sequence of EHMT1 can result in this condition in an individual.
 
==History and etiology==
Kleefstra syndrome is a new condition that has only been known about for a few years and there have been fewer than 200 cases, reported. Due to the lack of cases worldwide, however, the history behind the origination is unclear.<ref>Author, A. A., & Author, B. B. (29 December 2012). What is Kleefstra Syndrome. Retrieved from [http://www.kleefstrasyndrome.org/]</ref> Despite the associated effects of Kleefstra, there is insubstantial information regarding to the lethality of Kleefstra's. Most the of the documented cases are de novo with the exception of one case due to hereditary factors; however, some cases may be a result of chromosomal translocations. In the exception case, the mother transferred the EHMT1 point mutation on to her child as she was a carrier of this gene defect. According to Mitter, et al. (2012), the mother's phenotype of the NM_024757.4:c.2712+1G>A mutation displayed [[mosaicism]] at certain tissues. This mutation resulted in the disregard of exon 18 on the EHMT1 gene, as opposed to removing it through the spliceosomes. In another transcript, however, an intron was placed between exon 18 and 19 of the EHMT1 gene. The combination of the intron insertion and the mosaicism in the mother was transferred to the child, resulting in the pathogenesis of the disease.<ref>Mitter, D., et al. [http://www.ncbi.nlm.nih.gov/pubmed/23232695 "A mosaic maternal splice donor mutation in the EHMT1 gene leads to aberrant transcripts and to Kleefstra syndrome in the offspring."], ''European Journal of Human Genetics'', 2012 December 12</ref>
 
In the past, research showed that the austerity of the disease was directly proportional to the number of EHMT1 deletions prevalent in an individual. The greater the deletions, the greater the severity of the condition. However, in recent studies, 9q34 deletion syndrome occurs when the EHMT1 gene is non-functioning, as opposed to strictly deletion.<ref name="http://www.rarechromo.org/information/Chromosome%20%209/Kleefstra%20Syndrome%20FTNP.pdf">Rare Chromosome Disorder Support Group, [http://www.rarechromo.org/information/Chromosome%20%209/Kleefstra%20Syndrome%20FTNP.pdf "Kleefstra Syndrome"], ''Kleefstra Syndrome'', 2009</ref>
 
==Signs and symptoms==
'''Physical Symptoms'''
*Heart Defects
*Characteristics of Autism
*Genital defects (in males)
*Childhood hypotonia
*Respiratory infections
*Motor Delay
*Renal defects
 
'''Behavioural Symptoms'''
*Passiveness
*Sociability
*Aggression
**Biting, and/or hitting
*Moodiness
*Disliking routine changes
 
<ref name="Kleefstra, T., Nillesen, W.M., & Yntema, H.G. (2010). ''Kleefstra Syndrome''. Seattle: Gene Reviews." >Kleefstra, T., Nillesen, W.M., & Yntema, H.G. (2010). ''Kleefstra Syndrome''. Seattle: Gene Reviews.</ref>
<ref>Andrea Belanger, [http://www.mommiesofmiracles.com/kleefstra-syndrome/ "Kleefstra Syndrome"], ''Mommies of Miracles'', 2011</ref>
 
==Diagnosis==
Tests are either conducted at birth, or later in early childhood via: [[fluorescence in situ hybridization]] (FISH), [[multiplex ligation-dependent probe amplification]] (MLPA), [[array comparative genomic hybridization]] (aCGH), and EHMT1 sequencing.<ref name="http://www.rarechromo.org/information/Chromosome%20%209/Kleefstra%20Syndrome%20FTNP.pdf" />
 
FISH is a screening test that uses multicolour probes or [[comparative genomic hybridization]] to find any chromosome irregularities in a genome. It can be used for gene mapping, detecting aneuploidy, locating tumours etc. The multicolour probes attach to a certain DNA fragment.<ref>N/A [http://biohorizons.oxfordjournals.org/content/3/1/85.abstract  "Applications of fluorescence in situ hybridization (FISH) in detecting genetic aberrations of medical significance"], ''Bioscience Horizons'', 2010 February 27</ref> MLPA is a test that finds and records DNA copy change numbers through the use of PCR. MLPA can be used to detect tumours in the glial cells of the brain, as well as chromosomal abnormalities.<ref>Boots-Sprenger, S.,Corneilissen, S.,  Gijsen, S., Jeuken, J., & Wesseling, P. [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1867615/  "Multiplex Ligation-Dependent Probe Amplification"], ''Journal of Molecular Diagnostics'', 2006 September</ref> Array-based comparative genomic hybridization (aCGH) tracks chromosome deletions and or amplifications using fluorescent dyes on genomic sequences of DNA samples. The DNA samples (which are 25-80 base pairs in length) are then placed on slides to be observed under microscope.<ref>Peng, H.H., & Van den Veyyer, I.B. [http://www.medscape.org/viewarticle/585818_2 "HOW DOES ARRAY-BASED COMPARATIVE GENOMIC HYBRIDIZATION WORK?"], 2008</ref> Lastly, EHMT1 sequencing is a process in which a single-strand of DNA from the EHMT1 gene is removed, and DNA polymerase is added in order to synthesize complementary strands. In turn, this allows scientists to map out a person's DNA sequence allowing for a diagnosis to be made.<ref>N/A, [http://sop.washington.edu/pharmaceutics/dna-sequencing-center/principles-of-dna-sequencing.html "Principles of DNA Sequencing"], 2013</ref>
 
==Treatment==
Unfortunately, there are currently no existing treatments for Kleefstra syndrome.
 
==Epidemiology==
Kleefstra syndrome affects males and females equally and approximately, 75% of all documented cases are caused by Eu-HMTase1 disruptions while only 25% are caused by 9q34.3 deletions.<ref name="Kleefstra, T., Nillesen, W.M., & Yntema, H.G. (2010). ''Kleefstra Syndrome''. Seattle: Gene Reviews." />  There are no statistics on the affect the disease has on life expectancy due to the lack of information available.
 
==Research==
A study published by the [[American Journal of Human Genetics]] performed an EHMT1 mutation analysis on 23 patients that showed symptoms of q934 syndrome. The patients all varied in age. With respect to all the analyses, however, the clinical data focused on five patients, the majority being children. The first patient developed epilepsy early on in childhood, and had speech problems past age 8. He suffered from hypoplasia and had prominent facial features, such as lips and mouth. The second patient had no trace of [[mitral regurgitation]] (MR) in her family history, but had slight hypotonia. Patient three was the oldest at 36 who began to walk at age 3. She later gained weight at eleven and developed epilepsy in her late twenty's. The fourth patient had problems associated with eating as a young child and was diagnosed with slowed development. Patient five had behavioural issues and struggled with MR in addition to being overweight. The geneticists discovered three new mutations within the EHMT1 gene. The first was an interstitial deletion, while the second and third were a nonsense and frameshift. Their findings supported the notion that a disruption in the EHMT1 gene contributes to the pathogenesis of Kleefstra syndrome.<ref>Kleefstra, T., et al. [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559478/ "Loss-of-Function Mutations in Euchromatin Histone Methyl Transferase 1 (EHMT1) Cause the 9q34 Subtelomeric Deletion Syndrome"], ''American Journal of Human Genetics'', 2006 August</ref>
 
In another study published by the [[Journal of Medical Genetics]], DNA from forty patients were extracted and subjected to MLPA, FISH or EHMT1 sequencing. The forty patients were divided into two groups: 1 group of 16 patients with the 9q34 deletion, and 1 group of 24 with typical FISH/MPLA results. The geneticists examined how a missense mutation would affect the function of the DNA by looking at DNA models. After, they screened each person's DNA using one of three tests, the results for the first group showed six patients had the same deletion of the same size (700 kb). In the second group, after EHMT1 sequencing was performed, six [[intragenic]] mutations were discovered. The scientists investigating this experiment conclude these mutations may be infective agents for the disease. Lastly, the patients' behavioural, physical, and psychiatric symptoms are included on the data chart.<ref>Kleefstra, T., et al. [http://www.cmbi.ru.nl/~hvensela/EHMT1/HTML/EHMT1_Kleefstra.pdf "Further clinical and molecular delineation of the 9q Subtelomeric Deletion Syndrome supports a major contribution of EHMT1 haploinsufficiency to the core phenotype"], '' Journal of Medical Genetics'', 2009 December</ref>
 
==References==
{{Reflist}}
 
==External links==
*[http://www.kleefstrasyndrome.org/ The Kleefstra Syndrome website]
*[http://ghr.nlm.nih.gov/condition/kleefstra-syndrome The Genetics Home Reference website]
*[http://www.rarechromo.org/information/Chromosome%20%209/Kleefstra%20Syndrome%20FTNW.pdf The Rare Chromo website]
 
[[Category:Autosomal monosomies and deletions]]|Chromosome 9q deletion syndrome]]
*Chromosome 12, isochromosome 12p mosaic   
*Chromosome 12, isochromosome 12p mosaic   
*[[Tetrasomy|Chromosome 12p tetrasomy syndrome]]  
*[[Tetrasomy|Chromosome 12p tetrasomy syndrome]]  

Revision as of 19:22, 16 November 2015



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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [3]

Overview

The causes of abdominal pain vary with the distribution of the pain. The distribution can be determined by various methods, such as into either abdominal quadrants or nine sections.

Causes

Causes Based upon Location

Diffuse | Left Upper Quadrant | Left Flank | Left Lower Quadrant | Epigastric Region | Umbilical Region | Pelvic Region | Right Upper Quadrant | Right Flank | Right Lower Quadrant

Life Threatening Causes

Life-threatening causes include conditions that may result in death or permanent disability within the next 24 hours if left untreated.

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Common Causes

Causes by Organ System

Cardiovascular Anaphylaxis, aortic aneurysm, cholesterol emboli syndrome, chronic necrotizing vasculitis
Chemical / poisoning 1,2-dibromo-3-chloropropane, 1,2-dibromoethane, 1,2-dichloroethane, 1,4-dioxane, 1-propanol, 2,4,6-trinitrotoluene, 2,4-dichlorophenol, 2-acetylamino-fluorene, 2-butoxyethanol, 2-hexanone, 2-methyl-4-chlorophenoxyacetic acid, 2-nitropropane, 4-aminopyridine, 4-dimethylaminoazobenzene, 8-hydroxyquinoline, Acetaminophen poisoning, Acetic acid, Acetonitrile, acetylandromedol, acetylene tetrabromide, aconitum, acrinathrin, acrylamide, acrylic acid, acrylonitrile, acute mercury inhalation, adiponitrile, alanycarb, albitocin, alcohol, aldicarb, aldoxycarb, alicyclic hydrocarbons, aliphatic amines, aliphatic hydrocarbons, aliphatic hydrogenated hydrocarbons, allyl alcohol, allyl chloride, allylamines, allyxycarb, aloe poisoning, alpha-cypermethrin, aluminum phosphide, amanita phalloides, amanita polypyramis poisoning, amaranth, amidithion, amines, aminocarb, amiton, ammonium bifluoride, ammonium nitrate, amygdalin, amyl acetate, andromedotoxin, anthraquinone, antimony, arachnidism, aromatic amines, aromatic halogenated hydrocarbons, arsenic poisoning, arsenic trioxide, arsine, asphalt, athyl-gusathion, azalea poisoning, azinfosethyl, azinfos-methyl, azinphosmetile, azothoate, barium nitrate, barium, bendiocarb, benoxafos, benzene, benzoate, benzyl chloride, beryllium, beta-cyfluthrin, bifenthrin, bioallethrin, bioresmethrin, bipyridyl pesticides, bismuth, black locust poisoning, black nightshade poisoning, black widow spider bite, borates, boron hydrides, box thorn poisoning, bromide, bromophos, bufencarb, butacarb, butocarboxim, buttercup poisoning, cadmium, cadusafos, calcium hypochlorite, calcium oxide, camphor, caper spruge poisoning, captan, carbamate insecticide poisoning, carbofuran, carbon disulfide, carbon monoxide toxicity, carbon tetrachloride, carbophenothion, carbosulfan, carmine, caspofungin, chlorate salts, chlordane, chlorfenvinphos, chlorinated benzenes, chlorinated naphthalenes, chlorobenzene, chlorodiphenyl, chloroform, chloropicrin, chloroprene, chloropyrifos, chokecherry seed poisoning, christmas cherry poisoning, chromium, cicutoxin, ciguatera poisoning, clitocybe dealbata, cloethocarb, coastal leucothoe poisoning, cobalt, cobra poisoning, coffeeweed poisoning, Copper salts, Copper toxicity, Corsican hellebore poisoning, Coumaphos, Cresol, Cyanthoate, Cycad nut poisoning, cycasin, cyclochlorotine, cyfluthrin, cypermethrin, cyphenothrin, cypress spurge poisoning, Daffodil poisoning, Deadly nightshade (solanum dulcamara) poisoning, DeathDamas poisoning, Decarbofuran, Deltamethrin, Demeton, Demeton-methyl, Devil's snuff box poisoning, Dialifos, diazinon, dibromochloropropane, Dichlorvos, Dicresyl, Dicrotophos, Diethylene glycol,fluoride poisoning, grape seed extract, lead poisoning, oleander, parathion, pesticide, pyridine, snakebites, spider bite, tributyl phosphate
Dermatology Adnexal and skin appendage neoplasms, angioneurotic edema, Behcet's disease, Chiari-Frommel syndrome, chronic necrotizing vasculitis
Drug Side Effect Acetylsalicylic acid, acarbose, acipimox, acyclovir, alosetron, allopurinolaminocaproic acid, amlodipine and benazepril, ambenonium, amodiaquine, amphetamine abuse, amphotericin, anesthetic agent, antiarrhythmics, anticoagulants, antifungals, antihypertensives, antineoplastic agents, antiviral medicationaspirin, ativan withdrawal, atomoxetine, atovaquone, atovaquone-Proguanil, auranofin, azithromycin, aztreonam, basiliximab, benzodiazepine, bethanechol chloride, bezafibrate, bicalutamide, bosutinib, busulfan, butyrophenone, carbarsone, carbarylcaspofungin, cefdinir, cefixime, cephalosporin, cefuroxime, chloramphenicol, cidofovir, cimetidine, ciprofloxacin, cisapride, cladribine, clidinium, cyclopropane, clindamycin, clofibrate, codeine withdrawal, colchicine, contraceptive patch, cycloserine, cytarabine,dactinomycin, danazol, dantrolene, daptomycin, darvocet overdose, deferasirox, deferiprone, depo-provera, desmopressin,dexedrine overdose, didanosine, diflunisal, dimercaprol, donepezil, doxorubicin hydrochloride, drotrecogin alfa, dydrogesterone, ecallantide, enoxaparin, entacapone, Elosulfase alfa, erythromycin, ethcathinone, etodolac, etonogestrel, etoposide phosphate, febuxostat, fesoterodine, flucytosine, flurbiprofen, fluvastatin, ganirelix, glyburide and metformin, halofantrine, hydroxychloroquine, idarubicin, imiglucerase, indinavir, interferon beta- 1b, irinotecan hydrochloride, isoniazid, itraconazole, ivacaftor, ivermectin, ketorolac tromethamine, lactulose, lanreotide, lansoprazole, lanthanum carbonate, levonorgestrel, loperamide, lopinavir, loprazolam, loratadine, magnesium citrate, mebendazole, medroxyprogesterone, megestrol, mercaptopurine, mesna, methimazole, methotrexate, methylphenidate, metronidazole, mifepristone, miglitol, misoprostol, moxifloxacin, muscarine, nafcillin, naltrexone, naproxen sodium, naproxen and esomeprazole magnesium, natalizumab, neuromuscular-blocking drugs, niclosamide, nitazoxanide, norethindrone acetate and Ethinyl estradiol, norgestrel and ethinyl estradiol, octreotide injection, omeprazole, olsalazine, orlistat, oxcarbazepine, Pantoprazole, paromomycin sulfate, pasireotide, pazopanib hydrochloride, papaverine, piroxicam, pegaspargase, pentamidine Isethionate, pentavalent antimonial, pentostatin, perindopril, phenazocine, permethrin, pirfenidone, potassium iodide, polyethylene glycol-electrolyte solution (pEG-ES), potassium bicarbonate, potassium citrate, praziquantel, prazosin and polythiazide, primaquine phosphate, procainamide, procarbazine, progesterone, propylthiouracil, protirelin, rabeprazole, rasburicase, rifaximin, ritonavir, roxithromycin, sacrosidase, sargramostim, saquinavir mesylate, saxagliptin, secretin human, siltuximab, simvastatin, sorafenib, sucralfate, sulfasalazine, sunitinib, thiotepa, tianeptine, tigecycline, tolmetin, topiramate, topotecan, trametinib dimethyl sulfoxide, trastuzumab, tretinoin, triclofos, valacyclovir, vancomycin, vardenafil,vandetanib, vigabatrin, vinblastine, voriconazole, zafirlukast
Ear Nose Throat No underlying causes
Endocrine Addison's disease, adrenal crisis, adrenal disorders, adrenal gland hypofunction, adrenal hemorrhage, adrenal hyperplasia, adrenal insufficiency, Chiari-Frommel syndrome, congenital adrenal hyperplasia, cushing syndrome, diabetes mellitus type 2, diabetic gastroparesis, diabetic ketoacidosis, multiple endocrine neoplasia type 1
Environmental No underlying causes
Gastroenterologic Abdominal cramps, abdominal cutaneous nerve entrapment syndrome, abdominal mass, accessory pancreas, acute pancreatitis, appendicitis, autoimmune hepatitis, autoimmune pancreatitis, bacterial gastroenteritis, bowel obstruction, caecitis, carcinoid syndrome, celiac disease, Charcot's triad, cholangiocarcinoma, cholangitis, cholecystitis, choledochal cysts, choledocholithiasis, cholelithiasis, chronic erosive gastritis, curling ulcers, cushing ulcers, chronic hepatitis C, chronic hepatitis, chronic infectious diarrhea, chronic pancreatitis, cirrhosis, clostridial necrotizing enteritis, colitis, colorectal adenomatous polyposis, recessive, Colitis cystica profunda, colon cancer, familial, congenital lactase deficiency, congenital short bowel,colonic inertia, colonic polyps, colonic volvulus, colorectal cancer, Congenital hepatic porphyria, constipation, Crohn's disease, decreased intestinal motility, diarrhea, diverticulitis, duodenitis, dyspepsia, enteritis, epiploic appendagitis, gastric outlet obstruction, gastritis, gastroenteritis, gastrointestinal perforation, gastrointestinal stromal tumor, hemosuccus pancreaticus, ileitis, ileus, intestinal malrotation, intestinal pseudoobstruction, intussusception, irritable bowel syndrome, ischemic colitis, König's syndrome, Krukenberg tumor, malabsorption, Meckel's diverticulum, mesenteric ischemia, ogilvie syndrome, pancreatic cancer, pancreatitis, peptic ulcer, peritonitis, porcelain gallbladder, proctitis, pseudomembranous colitis, pseudomyxoma peritonei, toxic megacolon, ulcerative colitis, volvulus, Whipple's disease Cholangitis,
Genetic Adult cystic fibrosis, Baber's syndrome, Brachmann-de lange syndrome, Caroli disease, celiac disease, chester porphyria, Chromosome 12, isochromosome 12p mosaic, chromosome 12p tetrasomy syndrome, Chromosome 1p deletion syndrome, Chromosome 22q deletion syndrome, Chromosome 9q deletion syndrome, colon cancer, familial, colorectal adenomatous polyposis, recessive, congenital adrenal hyperplasia, congenital aplastic anemia, congenital lactase deficiency, congenital short bowel, coproporphyria, hereditary, Cornelia de Lange Syndrome, Crohn's disease, desmoid disease, hereditary, Gilbert's syndrome, Marfan syndrome, periodic fever syndrome, pyruvate carboxylase deficiency, Slone's disease
Hematologic Acute erythroleukemia, acute megacaryoblastic leukemia, acute myelofibrosis, acute myeloid leukaemia, acute non lymphoblastic leukemia, anemic, blood cancer, congenital aplastic anemia, congenital spherocytic anemia, porphyria
Iatrogenic Adjustable gastric band, Cinchonism, postcholecystectomy syndrome, short bowel syndrome, transfusion-associated graft versus host disease
Infectious Disease African horse sickness, amoebiasis, ancylostoma duodenale, angiostrongyliasis, anguillulosis, anisakis, ankylostomiasis,anthrax, arcobacter infection, arenavirus, ascariasis, ascending cholangitis,, astrovirus, Aseptic abscesses syndrome, Astroviridae, autoimmune hepatitis, autoimmune oophoritis, babesiosis, Bacillus cereus, bacterial gastroenteritis, bacterial septicemia,bartonella infections,balantidiasis, blastocystosis, Bornholm disease, Bothriocephalosis, botulism food poisoning, Brachylaima, Burkholderia pseudomallei, campylobacteriosis, Capillaria philippiensis infection, cat scratch fever, Cestoda, Clostridium difficile, Chagas disease, Chandipura virus, chlamydial infection, chronic hepatitis c, chronic hepatitis, Chronic infectious diarrhea, clonorchiasis, clostridial necrotizing enteritis, colibacillosis, Colorado tick fever, Colorado tick encephalitis, Cryptosporidium parvum, cryptosporidiosis, cyclosporiasis, cystitis, Dengue fever, dicrocoelium dendriticum fluke, diarrhea, diarrheagenic escherichia coli, dientamoeba fragilis, Ebola, Entamoeba histolytica, familial Mediterranean fever, fasciolopsiasis, fasciolosis, fungemia, Fusarium, Giardia lamblia, Hantavirus pulmonary syndrome, Helicobacter pylori infection, Henipavirus, hookworm, Hymenolepis infection, isosporiasis, leptospirosis, Mycobacterium avium complex, Norovirus, Opisthorchis infection, Paragonimus infection, Q fever, rheumatic fever, Rocky Mountain spotted fever, salmonellosis, scarlet fever, schistosomiasis, scombrotoxic fish poisoning, shigellosis, strongyloidiasis, toxocariasis, trichomoniasis, typhoid fever, Vibrio vulnificus, viral hepatitis , whipworm infection, yellow fever, yersiniosis
Musculoskeletal / Ortho No underlying causes
Neurologic Autonomic neuropathy,Charcot's triad, chronic fatigue syndrome
Nutritional / Metabolic Amyloidosis AL, aniseed, C1 esterase inhibitor deficiency, carageenan gum, carnitine-acylcarnitine translocase deficiency, cephalothoracic progressive lipodystrophy, chocolate, congenital lactase deficiency, congenital sucrose-isomaltose malabsorption, Cope's syndrome, coproporphyria, hereditary, pantothenic acid
Obstetric / Gynecologic Asherman syndrome, Autoimmune oophoritis, Braxton Hicks contractions, Breech presentation, Cervical cancer, Contraceptive patch,ectopic pregnancy, endometrial cancer, endometriosis, menstruation, ovarian cancer, ovarian cyst, Ovarian hyperstimulation syndrome, ovarian torsion, pelvic inflammatory disease, placental abruption, pregnancy, Salpingitis, uterine fibroids, uterine rupture, uterine sarcoma
Oncologic Abdominal neoplasms,Acute erythroleukemia, Acute leukaemia,Acute megacaryoblastic leukemia,Acute myelofibrosis,Acute non lymphoblastic leukemia, adenoma, islet cell, Adnexal and skin appendage neoplasms,Anal cancer, Angiomyolipoma, Appendix cancer, Bile duct cancer, Biliary tract cancer, Bladder cancer, blood cancer, Brinton disease, Burkitt lymphoma, Carcinoid syndrome,Cervical cancer,Childhood liver cancer, primaryCholangiocarcinoma, Chronic myelomonocytic leukemia,Chronic neutrophilic leukemia, Clear cell renal cell carcinomaCollecting duct carcinoma,Colon cancer, familial,Colorectal cancer, Desmoplastic small round cell tumor, liposarcoma, liver tumor, mesothelioma, sacrococcygeal teratoma
Ophthalmologic No underlying causes
Overdose / Toxicity Aflatoxin,clupeotoxism,dexedrine overdose, hypervitaminosis A
Psychiatric Bulimia nervosa, childhood-onset bipolar disorder, depression
Pulmonary Allergies, alveolar hydatid disease, anaphylaxis, acquired angioedema, angioneurotic edema, aspiration pneumonia, basal pneumonia, Chilaiditi syndrome, Churg-Strauss syndrome, congenital bronchogenic cyst, decompression sickness, empyema, pleuritis, pulmonary embolism, pulmonary infarction, tuberculosis
Renal / Electrolyte Bright's disease, Burnett's milk drinker's syndrome, chronic renal insufficiency, clear cell renal cell carcinoma, collecting duct carcinoma, congenital lactic acidosis, congenital megalo-ureter, continuous ambulatory peritoneal dialysis, Cope's syndrome, cystitis, hydronephrosis, hypercalcemia, hyperkalemia, hypocalcemia, nutcracker syndrome, polycystic kidney disease, pyelonephritis, ureterocele,urinary tract infection
Rheum / Immune / Allergy Allergies, alpha heavy chain disease, anaphylaxis, acquired angioedema, angiofollicular ganglionic hyperplasia, angioneurotic edema, autoimmune oophoritis, autoimmune pancreatitis, autoimmune thyroid disease, Behcet's disease, celiac disease, chronic fatigue syndrome, chronic necrotizing vasculitis, Churg-Strauss syndrome, citric acid intolerance, collagenous celiac disease, diffuse systemic sclerosis, systemic lupus erythematosus, polyarteritis nodosa
Sexual No underlying causes
Trauma No underlying causes
Urologic Bladder cancer, prostate cancer, prostatitis
Miscellaneous African horse sickness,baking powder, foreign body, side stitch, capillary leak syndrome, carbohydrate malabsorption

Causes in Alphabetical Order

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Acute Abdomen

Common causes of acute abdomen include:

Chronic Functional Abdominal Pain

Common causes of CFAP stem from:

References

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