5-alpha-reductase deficiency classification
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Overview
There are two isoforms of 5-alpha reductase named type 1 and type 2. Type 1 5-alpha reductase is found mostly in the skin and liver, which can get delivered to the prostate by systemic circulation. Type 2 is found only on prostatic tissue and is the most common form. So, 5-alpha-reductase deficiency is known as 5-alpha-reductase 2 deficiency.
Classification
There is no classification of 5-alpha reductase deficiency as type 2 5-alpha reductase deficiency is the most common one.[[1]]
References
- ↑ Walter KN, Kienzle FB, Frankenschmidt A, Hiort O, Wudy SA, van der Werf-Grohmann N; et al. (2010). "Difficulties in diagnosis and treatment of 5alpha-reductase type 2 deficiency in a newborn with 46,XY DSD". Horm Res Paediatr. 74 (1): 67–71. doi:10.1159/000313372. PMID 20395661.