3-Iodothyronamine

3-Iodothyronamine
IUPAC name	4-[4-(2-Amino-ethyl)-2-iodo-phenoxy]-phenol
Other names	T1AM
Identifiers
CAS number	712349-95-6
SMILES	OC1=CC=C(OC2=C(I)C=C(CCN)C=C2)C=C1
Properties
Molecular formula	C14H14INO2
Molar mass	355.17 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

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3-iodothyronamine (T₁AM) is an endogenous thyronamine. T₁AM is a high-affinity ligand for the trace amine-associated receptor TAAR1 (TAR1, TA1), a G protein-coupled receptor. In rodents, T₁AM causes a rapid drop in body temperature when injected.

T₁AM may be part of a signaling pathway to modulate cardiac function as the compound can induce negative inotropic effects and decrease cardiac output.

See also

• Trace amine

External links

• MeSH 3-iodothyronamine

References

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| group5 = Clinical Trials Involving 3-Iodothyronamine | list5 = Ongoing Trials on 3-Iodothyronamine at Clinical Trials.gov • Trial results on 3-Iodothyronamine • Clinical Trials on 3-Iodothyronamine at Google

| group6 = Guidelines / Policies / Government Resources (FDA/CDC) Regarding 3-Iodothyronamine | list6 = US National Guidelines Clearinghouse on 3-Iodothyronamine • NICE Guidance on 3-Iodothyronamine • NHS PRODIGY Guidance • FDA on 3-Iodothyronamine • CDC on 3-Iodothyronamine

| group7 = Textbook Information on 3-Iodothyronamine | list7 = Books and Textbook Information on 3-Iodothyronamine

| group8 = Pharmacology Resources on 3-Iodothyronamine | list8 = AND (Dose)}} Dosing of 3-Iodothyronamine • AND (drug interactions)}} Drug interactions with 3-Iodothyronamine • AND (side effects)}} Side effects of 3-Iodothyronamine • AND (Allergy)}} Allergic reactions to 3-Iodothyronamine • AND (overdose)}} Overdose information on 3-Iodothyronamine • AND (carcinogenicity)}} Carcinogenicity information on 3-Iodothyronamine • AND (pregnancy)}} 3-Iodothyronamine in pregnancy • AND (pharmacokinetics)}} Pharmacokinetics of 3-Iodothyronamine •

| group9 = Genetics, Pharmacogenomics, and Proteinomics of 3-Iodothyronamine | list9 = AND (pharmacogenomics)}} Genetics of 3-Iodothyronamine • AND (pharmacogenomics)}} Pharmacogenomics of 3-Iodothyronamine • AND (proteomics)}} Proteomics of 3-Iodothyronamine

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| group13 = Healthcare Provider Resources on 3-Iodothyronamine | list13 = Symptoms of 3-Iodothyronamine • Causes & Risk Factors for 3-Iodothyronamine • Diagnostic studies for 3-Iodothyronamine • Treatment of 3-Iodothyronamine

| group14 = Continuing Medical Education (CME) Programs on 3-Iodothyronamine | list14 = CME Programs on 3-Iodothyronamine

| group15 = International Resources on 3-Iodothyronamine | list15 = 3-Iodothyronamine en Espanol • 3-Iodothyronamine en Francais

| group16 = Business Resources on 3-Iodothyronamine | list16 = 3-Iodothyronamine in the Marketplace • Patents on 3-Iodothyronamine

| group17 = Informatics Resources on 3-Iodothyronamine | list17 = List of terms related to 3-Iodothyronamine

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