Clostridium difficile infection future or investigational therapies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Genetics

On December 14, 2005, researchers at McGill University in Montreal, Quebec, led by Dr. Ken Dewar and Dr. Andre Dascal and in collaboration with province-organized NPO Genome Quebec's research facility, announced they had cracked the genetic code of the highly virulent Quebec strain of C. difficile. This was accomplished by using ultra high-throughput sequencing technology. The tests involved doing 400,000 DNA parallel sequencing reactions which took the bacterium's genome apart and reassembled it so it could be studied.[1][2]

It is expected this will allow quicker detection of the disease and better treatment.

References

  1. Scientists map C. difficile strain - Institute of Public Affairs, Montreal