GNAO1

Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
Identifiers
Symbols	GNAO1 ; DKFZp686O0962; G-ALPHA-o; GNAO
External IDs	Template:OMIM5 Template:MGI HomoloGene: 39203
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, also known as GNAO1, is a human gene.

Further reading

• Raymond JR, Mukhin YV, Gelasco A; et al. (2002). "Multiplicity of mechanisms of serotonin receptor signal transduction". Pharmacol. Ther. 92 (2–3): 179–212. PMID 11916537.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Coupry I, Duzic E, Lanier SM (1992). "Factors determining the specificity of signal transduction by guanine nucleotide-binding protein-coupled receptors. II. Preferential coupling of the alpha 2C-adrenergic receptor to the guanine nucleotide-binding protein, Go". J. Biol. Chem. 267 (14): 9852–7. PMID 1349607.CS1 maint: Multiple names: authors list (link)
• Denker BM, Neer EJ, Schmidt CJ (1992). "Mutagenesis of the amino terminus of the alpha subunit of the G protein Go. In vitro characterization of alpha o beta gamma interactions". J. Biol. Chem. 267 (9): 6272–7. PMID 1556134.CS1 maint: Multiple names: authors list (link)
• Murtagh JJ, Eddy R, Shows TB; et al. (1991). "Different forms of Go alpha mRNA arise by alternative splicing of transcripts from a single gene on human chromosome 16". Mol. Cell. Biol. 11 (2): 1146–55. PMID 1899283.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yi F, Denker BM, Neer EJ (1991). "Structural and functional studies of cross-linked Go protein subunits". J. Biol. Chem. 266 (6): 3900–6. PMID 1899868.CS1 maint: Multiple names: authors list (link)
• Tsukamoto T, Toyama R, Itoh H; et al. (1991). "Structure of the human gene and two rat cDNAs encoding the alpha chain of GTP-binding regulatory protein Go: two different mRNAs are generated by alternative splicing". Proc. Natl. Acad. Sci. U.S.A. 88 (8): 2974–8. PMID 1901650.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gabrion J, Brabet P, Nguyen Than Dao B; et al. (1990). "Ultrastructural localization of the GTP-binding protein Go in neurons". Cell. Signal. 1 (1): 107–23. PMID 2518353.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lavu S, Clark J, Swarup R; et al. (1988). "Molecular cloning and DNA sequence analysis of the human guanine nucleotide-binding protein Go alpha". Biochem. Biophys. Res. Commun. 150 (2): 811–5. PMID 3124840.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zumbihl R, Breuiller-Fouché M, Carrette J; et al. (1995). "Up-regulation in late pregnancy of both Go1 alpha and Go2 alpha isoforms in human myometrium". Eur. J. Pharmacol. 288 (1): 9–15. PMID 7705473.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Grassie MA, Milligan G (1995). "Analysis of the relative interactions between the alpha 2C10 adrenoceptor and the guanine-nucleotide-binding proteins G(o)1 alpha and Gi 2 alpha following co-expression of these polypeptides in rat 1 fibroblasts". Biochem. J. 306 ( Pt 2): 525–30. PMID 7887906.
• Wu HC, Lin CT (1994). "Association of heterotrimeric GTP binding regulatory protein (Go) with mitosis". Lab. Invest. 71 (2): 175–81. PMID 8078296.
• Nitta K, Uchida K, Kawashima A; et al. (1994). "Identification of GTP-binding proteins in human glomeruli". Nippon Jinzo Gakkai shi. 36 (1): 9–12. PMID 8107314.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Georgoussi Z, Carr C, Milligan G (1993). "Direct measurements of in situ interactions of rat brain opioid receptors with the guanine nucleotide-binding protein Go". Mol. Pharmacol. 44 (1): 62–9. PMID 8393523.CS1 maint: Multiple names: authors list (link)
• Laugwitz KL, Allgeier A, Offermanns S; et al. (1996). "The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families". Proc. Natl. Acad. Sci. U.S.A. 93 (1): 116–20. PMID 8552586.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kawano N, Ito T, Kitamura H; et al. (1997). "Immunoexpression of the alpha subunit of a guanine nucleotide-binding protein (Go) in pulmonary neuroendocrine cells and neoplasms". Pathol. Int. 46 (6): 393–8. PMID 8869990.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• De Vries L, Elenko E, Hubler L; et al. (1997). "GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits". Proc. Natl. Acad. Sci. U.S.A. 93 (26): 15203–8. PMID 8986788.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Valenzuela D, Han X, Mende U; et al. (1997). "G alpha(o) is necessary for muscarinic regulation of Ca2+ channels in mouse heart". Proc. Natl. Acad. Sci. U.S.A. 94 (5): 1727–32. PMID 9050846.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chen C, Zheng B, Han J, Lin SC (1997). "Characterization of a novel mammalian RGS protein that binds to Galpha proteins and inhibits pheromone signaling in yeast". J. Biol. Chem. 272 (13): 8679–85. PMID 9079700.CS1 maint: Multiple names: authors list (link)
• Natochin M, Lipkin VM, Artemyev NO (1997). "Interaction of human retinal RGS with G-protein alpha-subunits". FEBS Lett. 411 (2–3): 179–82. PMID 9271201.CS1 maint: Multiple names: authors list (link)
• Busconi L, Denker BM (1998). "Analysis of the N-terminal binding domain of Go alpha". Biochem. J. 328 ( Pt 1): 23–31. PMID 9359829.