Hyperlipidemia NCEP recommendations for drug therapy of high-risk hyperlipidemia in children and adolescents
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Children and adolescents with high-risk hyperlipidemia require lipid-lowering drug therapy, particularly those with familial hypercholesterolemia, despite compliance with lifestyle recommendations .
NCEP recommendations for drug therapy of high-risk hyperlipidemia in children and adolescents
Original Recommendations of the National Cholesterol Education Program (NCEP) Expert Panel for Drug Therapy of High-Risk Hyperlipidemia in Children and Adolescents [1] (DONOT EDIT)
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Current Modifications
Male gender Strong family history of premature cardiovascular disease or events Presence of associated low high-density lipoprotein (HDL), high triglycerides, small dense LDL Presence of overweight or obesity and aspects of the metabolic syndrome Presence of other medical conditions associated with an increased atherosclerotic risk such as diabetes, human immunodeficiency virus (HIV) infection, systemic lupus erythematosus, organ transplantation, survivors of childhood cancer Presence of hypertension Current smoking and passive smoke exposure Presence of novel and emerging risk factors and markers, e.g., elevated lipoprotein(a), homocysteine, C-reactive protein
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References
- ↑ McCrindle BW, Urbina EM, Dennison BA, Jacobson MS, Steinberger J, Rocchini AP; et al. (2007). "Drug therapy of high-risk lipid abnormalities in children and adolescents: a scientific statement from the American Heart Association Atherosclerosis, Hypertension, and Obesity in Youth Committee, Council of Cardiovascular Disease in the Young, with the Council on Cardiovascular Nursing". Circulation. 115 (14): 1948–67. doi:10.1161/CIRCULATIONAHA.107.181946. PMID 17377073.