Tuberculosis surgery

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

Surgery can be indicated, particularly to drain abscesses , empyema, venticular shunt in tubercular meningitis, surgical resection of tissues affected in abdominal tuberculosis, stabilize the spine in case of Pott's disease , lobectomy, pneumonectomy, pericardiocentesis or surgical repair of pericardium.

Surgery

Pulmonary tuberculosis

  • Pneumonectomy or removal of one entire lung is reserved as a treatment option for serious conditions of tuberculosis which are drug resistant. [1]
  • Lobectomy or removal of lobes of lung are used to treat drug resistant tuberculosis if it has affected only a part of lung.
  • Surgery may be necessary to remove cold abscesses and tuberculous empyema.
  • Segmentectomy or wedge resection is used in certain cases for treating tuberculosis resistant to anti tubercular drugs.

Renal tuberculosis

Surgery is necessary to manage the urinary obstruction in genito urinary tuberculosis. 3 most common sites which can cause urinary obstruction is as follows. [2]

  • Pelvi- ureteral junction
  • Calyx
  • Lower end of ureter
Types of surgery Proceedure
Cavernotomy It involves removal of avascular caeseous material which helps in preventing complications like abscess rupture. It has got excellent prognosis
Partial nephrectomy This was an old technique to remove the affected tissue. Recently the drug regimen helps to heal the calyx and hence partial nephrectomy is not widely practised now.
Nephrectomy Chief indication of nephrectomy is obstruction of pelvi-ureteric junction. Plastic surgery of pelvi uretric junction is also an option for it. Drianage improves the treatment
Excision of stricture and re implantation of ureter into the bladder. This is another conservative surgical management which has shown promising results.

Spinal tuberculosis

  • Biopsy is used to make a diagnosis.
  • Gross instability and neurological complications are treated by decompression and fusion of the anterior segments.
  • Joint damage may be repaired by late surgery and arthrodosis.

The main stay of treatment for skeletal tuberculosis is antibiotics and surgery. Surgical management of tuberculosis of spine of various stages are given below. [1]

Stage Treatment
Stage 1 (synovitis)
   Chemotherapy
   Rest
   Restriction of movements
   Splinting
Stage 2 (Early arthritis)
   Chemotherapy
   Rest
   Restriction of movements
   Splinting
   Synovectomy
Stage 3 (Advanced arthritis)
   Chemotherapy
   Osteotomy
   Arthrodesis
   Arthroplasty
Stage 4 (Advanced arthritis)
   Chemotherapy
   Osteotomy
   Arthrodesis
   Arthroplasty
Stage 5
   Chemotherapy
   Osteotomybr>   Arthrodesis
   Arthroplasty

Tuberculosis pericarditis

Surgical removal or repair of infected sac of pericardium is often the treatment of choice if it is not responding to antibiotics. There are two different types of surgical procedures: Open surgical removal and pericardiocentesis. Pericardiectomy is reserved for patients who worsen even after 4-8 weeks of anti tuberculous therapy. [3]

Tuberculosis meningitis

Surgical placement of shunt is used to drain the fluid and prevent the damage to the brain caused by a build-up of fluid.

Abdominal tuberculosis

Surgical resection of intestine affected by tuberculosis which is not responding to multidrug regimen helps in preventing complications of abdominal tuberculosis

Surgical interventions in patients with MDR-TB

In patients with RR-TB or MDR-TB patients, elective partial lung resection (lobectomy or wedge resection) may be used alongside a recommended MDR-TB regimen (conditional recommendation, very low certainty in the evidence).

References

  1. 1.0 1.1 "Surgery tuberculosis" (PDF).
  2. HANLEY HG (1963). "TREATMENT OF RENAL TUBERCULOSIS". Br Med J. 2 (5373): 1611–2. PMC 1873944. PMID 14066180.
  3. Bozbuga N, Erentug V, Eren E, Erdogan HB, Kirali K, Antal A; et al. (2003). "Pericardiectomy for chronic constrictive tuberculous pericarditis: risks and predictors of survival". Tex Heart Inst J. 30 (3): 180–5. PMC 197314. PMID 12959199.

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