Heart murmur resident survival guide

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nuha Al-Howthi, MD[2]

Overview

This section provides a short and straight to the point overview of the disease or symptom. The first sentence of the overview must contain the name of the disease.

Causes

Life Threatening Causes

Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.

• papillary muscle rupture complicating acute myocardial infarction (MI)
• rupture of chordae tendineae.
• infective endocarditis
• blunt chest wall trauma

Common Causes

• systolic murmur
  • Ejection murmurs
    • Functional
      • Still's murmur and its adult variant
      • Flow murmur emanating from the root of the pulmonary artery
      • Murmur associated with high cardiac output states
      • Flow murmurs associated with aortic or pulmonary valvular insufficiency
    • Organic
      • Valvular aortic stenosis
      • Aortic sclerosis
      • Discrete subvalvular aortic stenosis (web or tunnel)
      • Supravalvular aortic stenosis
      • Hypertrophic obstructive cardiomyopathy
      • Pulmonary valvular stenosis
      • Pulmonary infundibular stenosis
      • Atrial septal defect
      • Tetralogy of Fallot
  • Regurgitant murmurs
    • Functional: none
    • Organic:
      • Mitral regurgitation:
        • Rheumatic
        • Papillary muscle dysfunction
        • Mitral valve prolapse
        • Acute
      • Tricuspid regurgitation:
        • Chronic
        • Acute
      • Ventricular septal defect
        • Roger's type (small and large)
          • Without pulmonary hypertension
          • With pulmonary hypertension
        • Slitlike
    • Extracardiac sounds simulating systolic heart murmurs
      • Subclavian (supraclavicular/brachiocephalic) murmur
      • Internal mammary soufflé
      • Carotid artery bruits
      • Coarctation of the aorta
      • Murmurs emanating from a dilated aortic or pulmonary artery root
      • Patent ductus arteriosus with pulmonary hypertension
        
• diastolic murmur
  • Aortic regurgitation
  • Pulmonary valve regurgitation
  • Mitral rumble
    • Obstruction to flow
      • Mitral stenosis (rheumatic, congenital)
      • Left atrial myxoma
      • Cor triatriatum
      • Localized pericardial constriction
    • Increased flow
      • Mitral regurgitation
      • Ventricular septal defect
      • Patent ductus arteriousus
      • Complete heart block
  • Tricuspid rumble
    • Obstruction to flow
      • Tricuspid stenosis (rheumatic, Ebstein's anomoly, carinoid)
      • Right atrial myxoma
      • Localized pericardial constriction
    • Increased flow
      • Atrial septal defect
      • Tricuspid regurgitation
• continuous murmur
  • THORACIC:
    • Precordial
      • Patent ductus arteriosus
      • Coronary arteriovenous fistulas
      • Sinus of Valsalva aneurysm ruptured into right cavities
      • Atrial septal defect associated with abnormalities that cause increased pressure in the left atrium
      • Left coronary artery origin from pulmonary artery anomaly
      • Continuous murmur at intern mammary artery
    • Extra Precordial
      • Coarctation of the aorta
      • Pulmonary atresia
      • Pulmonary arteriovenous fistula
      • Truncus arteriosus
      • Anomalies of origin of the pulmonary artery
  • EXTRATHORACIC:
    • Venous hum
    • Cruveilhier-Baumgarten sindrom
    • Sever arterial stenosis
    • Extrathoracic arteriovenos fistulas

Diagnosis

Shown below is an algorithm summarizing the Strategy for evaluating heart murmurs according the the ACC/AHA Guidelines for the Management of Patients With ValvularHeart Disease.

Cardiac murmur

Systolic Murmur

Diastolic Murmur

Continuous Murmur

❑ Midsystolic, grade 2 or less

❑Early systolic, ❑ Midsystoilic grade 3 or more, ❑ Late systolic, ❑ Holosystolic murmur

❑ Venous hum ❑ Mammary souffle of pregnancy

Echocardiography Class I ❑ Echocardiography is recommended for asymptomatic patients with diastolic murmurs, continuous murmurs, holosystolic murmurs, late systolic murmurs,murmurs associated with ejection clicks or murmurs that radiate to the neck or back.(Level of Evidence: C) ❑ Echocardiography is recommended for patients with heart murmurs and symptoms or signs of heart failure, myocardial ischemia/infarction, syncope,thromboembolism, infective endocarditis, or other clinical evidence of structural heart disease.(Level of Evidence: C) ❑ Echocardiography is recommended for asymptomatic patients who have grade 3 or louder mid peaking systolic murmurs.(Level of Evidence: C) Class IIa ❑ Echocardiography can be useful for the evaluation of asymptomatic patients with murmurs associated with other abnormal cardiac physical findings or murmurs associated with an abnormal ECG or chest X-ray.(Level of Evidence: C) ❑ Echocardiography can be useful for patients whose symptoms and/or signs are likely non cardiac in origin but in whom a cardiac basis cannot be excluded by standard evaluation.(Level of Evidence: C) Class III ❑ Echocardiography is not recommended for patients who have a grade 2 or softer midsystolic murmur identified as innocent or functional by an experienced observer.(Level of Evidence: C)

Asymptomatic and no associated findings

❑ Symptomatic or other signs of cardiac diseases, ❑ If an ECG or X-ray has been obtained and is abnormal

catheterization and angiography if appropriate

No further workup

No further workup

Complete Diagnostic Approach

Obtain a Detailed History The history, and associated physical examination findings provide additional clues by which the significance of a heart murmur can be established Accurate bedside identification of a heart murmur can inform decisions regarding the indications for noninvasive testing and the need for referral to a cardiovascular specialist. ❑ Address specific patient symptoms and complaints ❑ Obtain review of systems relevant to Cardiovascular system ❑ Headache ❑ Dizziness ❑ Syncope/presyncope ❑ Chest pain / Angina ❑ Palpitations ❑ Dyspnea ❑ Cough ❑ Abdominal pain ❑ Peripheral edema ❑ Dyspnea on exertion ❑ Fatigue ❑ Orthopnea ❑ Paroxysmal nocturnal dyspne ❑ History of alcohol use ❑ History of smoking Past Medical History ❑ History of previous medical diagnoses / past medical complaints / hospitalizations and surgeries ❑ Cardiovascular disease ❑ Hypertension ❑ Bicuspid aortic valve ❑ Rheumatic fever ❑ History of diabetes mellitus ❑ History of hypertension Medications ❑ Current prescribed medications ❑ Previous intake of medications and reason for discontinuation ❑ History of drug adverse effects Allergies ❑ Known drug allergies ❑ Known environmental/food allergies Family history ❑ Family history of cardiovascular disease Social History ❑ Overall living situation ❑ Occupation ❑ Exercise ❑ Diet (general) ❑ Smoking history ❑ Alcohol use ❑ Recreational drug use ❑ Stress ❑ Sexual lifestyle & contraceptive methods

Examine the patient: ❑ Pulse ❑ Blood pressure ❑ Temperature ❑ Respiratory rate Skin: ❑ Cyanosis ❑ Peripheral edema Cardiovascular system: Palpation: ❑ Apical impulse Auscultation: ❑ Heart sounds ❑ Murmur Respiratory system: ❑ Crackles or rales ❑ Tachypnea Abdominal system: ❑ Hepatojugular reflex ❑ Hepatomegaly ❑ Ascites

❑ The accurate timing of heart murmurs is the first step in their identification. ❑ Duration and Character: The configuration of a heart murmur may be described as crescendo, decrescendo, crescendo-decrescendo, or plateau. ❑ Intensity ❑ The intensity of a heart murmur is graded on a scale of 1–6 ❑ A grade 1 murmur is very soft and is heard only with great effort. ❑ A grade 2 murmur is easily heard but not particularly loud. ❑ A grade 3 murmur is loud but is not accompanied by a palpable thrill over the site of maximal intensity. ❑ A grade 4 murmur is very loud and is accompanied by a thrill. ❑ A grade 5 murmur is loud enough to be heard with only the edge of the stethoscope touching the chest. ❑ A grade 6 murmur is loud enough to be heard with the stethoscope slightly off the chest. ❑ Murmurs of grade 3 or greater intensity usually signify important structural heart disease. ❑ The intensity of a heart murmur may be diminished by any process that increases the distance between the intracardiac source and the stethoscope on the chest wall, such as obesity, obstructive lung disease, and a large pericardial effusion. The intensity of a murmur also may be misleadingly soft when cardiac output is reduced significantly or when the pressure gradient between the involved cardiac structures is low. ❑ Location and Radiation ❑ Recognition of the location and radiation of the murmur helps facilitate its accurate identification. ❑ Adventitious sounds, such as a systolic click or diastolic snap, or abnormalities of S1 or S2 may provide additional clues. ❑ Interventions Used to Alter the Intensity of Cardiac Murmurs ❑ Respiration: Right-sided murmurs generally increase with inspiration. Left-sided murmurs usually are louder during expiration. ❑ Valsalva maneuver: Most murmurs decrease in length and intensity. Two exceptions are the systolic murmur of HCM, which usually becomes much louder, and that of MVP, which becomes longer and often louder. ❑ Exercise: Murmurs caused by blood flow across normal or obstructed valves (e.g., PS and MS) become louder with both isotonic and isometric (handgrip) exercise. Murmurs of MR, VSD, and AR also increase with handgrip exercise. ❑ Positional changes: With standing, most murmurs diminish, 2 exceptions being the murmur of HCM, which becomes louder, and that of MVP, which lengthens. With brisk squatting, most murmurs become louder, but those of HCM and MVP usually soften and may disappear. Passive leg raising usually produces the same results as brisk squatting. ❑ Pharmacological interventions: During the initial relative hypotension after amyl nitrite inhalation, murmurs of MR, VSD, and AR decrease, whereas murmurs of AS increase. During the later tachycardia phase, murmurs of MS and right-sided lesions also increase. This intervention may thus distinguish the murmur of the Austin-Flint phenomenon from that of MS. The response in MVP often is biphasic (softer then louder thancontrol).

Systolic Murmur

Diastolic murmur

Continuous murmur

early systolic murmur

Holo-systolic murmur

Mid-systolic murmur

Treatment

Shown below is an algorithm summarizing the treatment of [[disease name]] according the the [...] guidelines.

Do's

• The content in this section is in bullet points.

Don'ts

• The content in this section is in bullet points.

References

Template:WikiDoc Sources