Wild-type (senile) amyloidosis overview
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Wild-type (senile) amyloidosis was previously referred to as senile systemic amyloidosis (SSA) or senile cardiac amyloidosis (SCA). It is characterized by the deposition of transthyretin (TTR), a protein that is primarily made in the liver, throughout the body. The most common location of deposition of this protein is the heart. As the name suggests, this disease is encountered among the elderly population. The fact that this condition is more commonly found in the elderly population complicates the diagnosis making process as this affected population is usually at risk of and/or affected by cardiovascular diseases.