Cystic Tumor of the Atrioventricular Node
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mandana Chitsazan, M.D. [2]
Synonyms and keywords: Mesothelioma of the atrioventricular node
Overview
Historical Perspective
Cystic tumor of the atrioventricular (AV) node was first reported by Armstrong and Mönckeberg in 1911. [1]
Classification
There is no established system for the classification of [disease name].
OR
There is no established system for the staging of [malignancy name].
CTAVN are rare. They are choristomatous lesions composed of ectopic gland located in the atrioventricular node and the atrial septum.
Other midline defects are seen in 10% of the patients.
Considering their location, congenital heart block is a typical manifestation.
The most common initial manifestation is sudden death.Most CTAVN are diagnosed incidentally at autopsy.
There are a few case reports of successfully resected atrioventricular nodal tumors.
Pathophysiology
[Disease or malignancy name] arises from [cell name]s, which are [cell type] cells that are normally involved in [function of cells].
On gross pathology, small multiocular cysts are characteristic findings of CTAVN.The tumor may be invisible from the endocardial surface of the heart. Therefore, sectioning through the infero-medial tricuspid annulus might be required.[2] [3]
On microscopic histopathological analysis, solid cell nests and cystic structures lined by flattened cuboidal or squamous epithelium mixed with rare neuroendocrine cells are characteristic findings of CTAVN.</ref> [2]
Primary Prevention
There are no established measures for the primary prevention of cystic tumor of the atrioventricular tumor.
Secondary Prevention
There are no established measures for the secondary prevention of cystic tumor of the atrioventricular node.
References
- ↑ Armstrong H, Mönckeberg JG (1911). "Herzblock, bedingt durch primären Herztumor, bei einem 5 jährigen Kinde". Dtsch Arch Klin Med. 102: 144–146.
- ↑ 2.0 2.1 Miller DV (2012). "Cardiac Tumors". Surg Pathol Clin. 5 (2): 453–83. doi:10.1016/j.path.2012.04.007. PMID 26838113.
- ↑ Burke A, Tavora F (2016). "The 2015 WHO Classification of Tumors of the Heart and Pericardium". J Thorac Oncol. 11 (4): 441–52. doi:10.1016/j.jtho.2015.11.009. PMID 26725181.