PVC induced cardiomyopathy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Historical perspective

In 1998, a study demonstrated that treating patients with frequent PVCs ( > 20,000 per day ) and ventricular dysfunction with amiodarone could significantly improve LVEF.[1] This result led to the initial assumption that frequent PVCs might cause a reversible form of cardiomyopathy and thus, the concept of PVC-induced cardiomyopathy as a separate entity was formed.

Pathophysiology

Causes and risk factors

Natural history, complications, and prognosis

History and symptoms

Physical exam

Electrocardiogram

Echocardiography

Treatment

References

  1. Duffee DF, Shen WK, Smith HC (1998). "Suppression of frequent premature ventricular contractions and improvement of left ventricular function in patients with presumed idiopathic dilated cardiomyopathy". Mayo Clin Proc. 73 (5): 430–3. doi:10.1016/S0025-6196(11)63724-5. PMID 9581582.