Esophagitis risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Common risk factors in the development of esophagitis are immunosuppression, alcohol use, smoking, excessive vomiting, certain medications, and surgery or radiation to the chest.

Risk Factors

The following increase the risk of esophagitis:

Individuals with weakened immune systems due to HIV and certain medications (such as corticosteroids) may develop infections that lead to esophagitis.

The risk factors of EoE are as follows:[1][2][3][4][5]

  • Age- EoE has a bimodal age distribution common in both children and adults.
  • Sex- Males are more prone to EoE than the females.
  • Weather- Cold and dry climate trigger EoE.
  • Location- EoE is common in people with a history of European ancestry.
  • Season- Summer and fall, this is because people stay outdoors during this time and the higher levels of the pollen and the other allergens during these seasons.
  • Family history- EoE runs in the family and it is more common in people with a positive family history of the EoE.
  • History of allergies- EoE is very common in patient with a history of allergies such as asthma, industrial exposures, environmental allergies, chronic respiratory disease, food allergies and atopic dermatitis.

Reflux Esophagitis

Common risk factors of GERD include the following:

References

  1. "Genetic dissection of eosinophilic esophagitis provides insight into disease pathogenesis and treatment strategies. - PubMed - NCBI".
  2. "www.ncbi.nlm.nih.gov" (PDF).
  3. "Genetics of Eosinophilic Esophagitis - FullText - Digestive Diseases 2014, Vol. 32, No. 1-2 - Karger Publishers".
  4. Furuta GT, Katzka DA (2015). "Eosinophilic Esophagitis". N. Engl. J. Med. 373 (17): 1640–8. doi:10.1056/NEJMra1502863. PMC 4905697. PMID 26488694.
  5. Kocsis D, Tulassay Z, Juhász M (2015). "[Dietary and pharmacological aspects of eosinophilic esophagitis]". Orv Hetil (in Hungarian). 156 (23): 927–32. doi:10.1556/650.2015.30164. PMID 26027600.


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