Filariasis historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Lymphatic Filariasis is thought to have affected humans since approximately 1500-4000 years ago and the first documentation of symptoms occurred in the 16th century, when Jan Huygen Linschoten wrote about the disease during the exploration of Goa. Dr. Rodolfo Robles Valverde's study on patients with river blindness in Guatemala led to the discovery that the disease is caused by filaria of O. volvulus, and sheds light on the life cycle and transmission of the parasite.
Historical Perspective
- In the 16th century, Jan Huygen Linschoten put an overall idea about filariasis during his trip to Goa. After that, more reports of the disease came out from Asia and Africa.
- In 1866, Timothy Lewis continued what Jean-Nicolas Demarquay and Otto Henry Wucherer started 3 years before him when they detected microfilariae in hydrocele. Timothy made connection between these microfilariae and the elephantiasis when he discovered the presence of the microfilariae in the blood and urine.
- In 1876, Joseph Bancroft discovered the adult round worm which is responsible for filariasis and was named Wuchereria Bancrofti .
- In 1877, Patricj Manson described the life cycle of the arthropod vector causing the disease when he discovered the microfilariae in the mosquitoes. It was also the discovery of arthropod to be the vector. [1]
- In 1900, George Carmichael described how the disease is transmitted when he discovered the presence of the worm in the mosquito vector.
- In 1915. Dr. Rodolfo Robles Valverde made a study of patients of river blindness in Guatemala. This study resulted in discovery of O. volvulus as the filaria causing the disease. [2]
- ↑ Template:Cite we
- ↑ ROBLES R. Enfermedad nueva en Guatemala. La Juventud Médica 1917; 17: 97-115.