Hand-foot-and-mouth disease natural history

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]

Complications

Common complications of hand-foot and mouth disease include:

  • Encephalitis (swelling of the brain) which can be fatal
  • A polio-like paralysis, result even more rarely.
  • Fingernail and toenail loss
  • Occurring mostly in children within 4 weeks of their having hand, foot, and mouth disease (HFMD).
  • At this time, it is not known whether the reported nail loss is or is not a result of the infection.
  • However, in the reports reviewed, the nail loss has been temporary and nail growth resumed without medical treatment.[1]

Other complications include:

Complications from the virus infections that cause HFMD are not common, but if they do occur, medical care should be sought.

Prognosis

Generally, complete recovery occurs in 5 to 7 days.

References

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