Goodpasture syndrome medical therapy
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Goodpasture syndrome Microchapters |
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Diagnosis |
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Treatment |
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Goodpasture syndrome medical therapy On the Web |
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Risk calculators and risk factors for Goodpasture syndrome medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The mainstay of therapy for Goodpasture syndrome is corticosteriods, cyclophosphamide and plasmapheresis.
Medical Therapy
Goodpasture’s syndrome responds well to treatment with corticosteroids and immunosuppressants. These drugs dampen the body's normal immune response. A serious side effect of this is that the patient may become more susceptible to infections. The concentration of anti-GBM antibodies in the blood may be reduced by apheresis to remove blood plasma and its replacement with an isotonic salt and protein solution. This course of treatment usually lasts between three and six months.
Antibiotic treatment of lung infection and stopping smoking may also help to reduce lung haemorrhaging.
However, none of these can reverse permanent kidney damage and so for patients who have suffered this, renal transplant once the disease has subsided may be the only option.