Biliary cystadenoma and cystadenocarcinoma pathophysiology

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Pathophysiology

Biliary cystadenomas are cystic neoplasms that may be either unilocular or multilocular. Only rarely are they found in the extrahepatic biliary tree and gallbladder (see extrahepatic biliary cystadenoma). Histologically cystadenomas are composed of multiple cysts lined by cuboidal or columnar epithelium that resembles normal biliary epithelium.

The vast majority of these neoplasms are intrahepatic (97%) with a small proportion extrahepatic (3%).

Some biliary cystadenomas may rarely develop into a cystadenocarcinoma.

Microscopic Pathology

At histologic analysis, cystadenomas have multiple loculations lined by cuboidal or columnar epithelium that resembles biliary epithelium.

References

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