Sandbox ID gallery

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ImageName.jpg | Description <br> [http://phil.cdc.gov/Phil/ <font size="-2">''Adapted from CDC''</font>]
ImageName.jpg | Description <br> [http://www.cdc.gov/dpdx/ <font size="-2">''Adapted from CDC''</font>]
ImageName.jpg | Description <br> [http://www.cdc.gov/ticks/geographic_distribution.html <font size="-2">''Adapted from CDC''</font>]

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Sexually Transmitted Disease Gallery

Bacterial vaginosis

• 

  This photomicrograph of a vaginal smear specimen depicts two epithelial cells, a normal cell, and an epithelial cell with its exterior covered by bacteria giving the cell a roughened, stippled appearance known as a “clue cell”. Clue cells are epithelial cells that have had bacteria adhere to their surface, obscuring their borders, and imparting a stippled appearance. The presence of such clue cells is a sign that the patient has bacterial vaginosis. Adapted from CDC

• 

  This photograph depicted a single Gardnerella vaginalis, formerly Haemophilus vaginalis, or Corynebacterium vaginalis, bacterial colony.The vagina is normally colonized by Lactobacillus spp., which help to regulate the region’s pH, maintaining it in the low range, thereby, inhibiting the growth of potentially-pathogenic organisms. The Gram-positive Gardnerella vaginalis bacterium is one such organism, and is a common cause for bacterial vaginosis (BV). Adapted from CDC

• 

  This photograph depicted a single Gardnerella vaginalis, formerly Haemophilus vaginalis, or Corynebacterium vaginalis, bacterial colony. The vagina is normally colonized by Lactobacillus spp., which help to regulate the region’s pH, maintaining it in the low range, thereby, inhibiting the growth of potentially-pathogenic organisms. The Gram-positive Gardnerella vaginalis bacterium is one such organism, and is a common cause for bacterial vaginosis (BV). Adapted from CDC

• 

  This photomicrograph reveals bacteria adhering to vaginal epithelial cells known as “clue cells”. “Clue cells” are epithelial cells that have had bacteria adhere to their surface, obscuring their borders, and imparting a stippled appearance. The presence of such clue cells is a sign that the patient has bacterial vaginosis. Adapted from CDC

• 

  This photomicrograph reveals bacteria adhering to vaginal epithelial cells known as “clue cells”. “Clue cells” are epithelial cells that have had bacteria adhere to their surface, obscuring their borders, and imparting a stippled appearance. The presence of such clue cells is a sign that the patient has bacterial vaginosis. Adapted from CDC

Chlamydia

• 

  Under a relatively-low magnification of 63X, this Gram-stained photomicrograph of a vaginal specimen revealed the presence of squamous epithelial cells, polymorphonuclear leukocytes (PMNs), or white blood cells (WBCs), and numerous Gram-positive bacilli, or rods. Vaginal specimens are reviewed for many reasons including the Pap test, tests for STDs such as human papilloma virus (HPV) andChlamydia trachomatis , as well as others. The vagina is normally home to a number of bacterial organisms, referred to as vaginal microbiota, or vaginal microflora, composed primarily of rod-shaped Lactobacillus spp., as well as others. Adapted from CDC

• 

  Photomicrograph of Chlamydia trachomatis taken from a urethral scrape. Untreated, chlamydia can cause severe, costly reproductive and other health problems including both short- and long-term consequences, i.e. pelvic inflammatory disease (PID), infertility, and potentially fatal tubal pregnancy. Adapted from CDC

• 

  This McCoy cell monolayer micrograph reveals a number of intracellular C. trachomatis inclusion bodies; Magnified 50X. The intracellular inclusion body represents the replication phase of the Chlamydia spp. organisms, whereupon, the reorganized reticulate body (RB) multiplies through binary fission into 100-500 new RBs, which mature into elementary bodies (EB). Adapted from CDC

• 

  This image reveals a close view of a patient’s left eye with the upper lid retracted in order to reveal the inflamed conjunctival membrane lining the inside of both the upper and lower lids, due to what was determined to be a case of inclusion conjunctivitis, a type of conjunctival inflammation caused by the bacterium, Chlamydia trachomatis. Inclusion conjunctivitis, also known as chlamydial conjunctivitis, is more common in newborns. Symptoms include redness of the eye(s), swelling of the eyelids, and discharge of pus, usually 5 to 12 days after birth. Adapted from CDC

• 

  This photomicrograph depicts HeLa cells infected with Type-A Chlamydia trachomatis, Magnified 400X. The cell line of choice is McCoy, however a particular strain of HeLa cells, i.e. HeLa 299-24, can be used to culture C. trachomatis. For identification, either iodine or fluorescent antibody (FA) stains are usually used. Adapted from CDC

• 

  Under a low magnification of 12.5X, this photomicrograph reveals McCoy cell monolayers with Chlamydia trachomatis inclusion bodies. Chlamydia, caused by Chlamydia trachomatis, is the most common bacterial sexually transmitted infection. Using cell cultures from the McCoy cell line is one methods implemented in diagnosing Chlamydial infections. Adapted from CDC

• 

  This photomicrograph reveals McCoy cell monolayers with Chlamydia trachomatis inclusion bodies; Magnified 50X. Chlamydia, caused by Chlamydia trachomatis, is the most common bacterial sexually transmitted infection. Using cell cultures from the McCoy cell line is one methods implemented in diagnosing Chlamydial infections.Adapted from CDC

• 

  This photomicrograph reveals McCoy cell monolayers with Chlamydia trachomatis inclusion bodies; Magnified 200X. Chlamydia, caused by Chlamydia trachomatis, is the most common bacterial sexually transmitted infection. Using cell cultures from the McCoy cell line is one methods implemented in diagnosing Chlamydial infections. Adapted from CDC

Gonorrhea

• Description Adapted from CDC

  Description Adapted from CDC

Genital Herpes

• Description Adapted from CDC

  Description Adapted from CDC

HIV/AIDS

• Description Adapted from CDC

  Description Adapted from CDC

Human papillomavirus

• Description Adapted from CDC

  Description Adapted from CDC

Lymphogranuloma venereum

• Description Adapted from CDC

  Description Adapted from CDC

Pubic lice infestation

• 

  This 2006 image depicted five body lice, Pediculus humanus var. corporis, which from left to right included three nymphal-staged lice, beginning with a stage N1, then N2, and thirdly a N3-staged nymph, followed by an adult male louse, and finally an adult female louse. Lice are parasitic insects that can be found on people's heads, and bodies, including the pubic area. Human lice survive by feeding on human blood. Lice found on each area of the body are different from each other. The three types of lice that live on humans are: Pediculus humanus capitis (head louse), Pediculus humanus corporis (body louse, clothes louse) and Phthirus pubis ("crab" louse, pubic louse). Only the body louse is known to spread disease. Lice infestations are spread most commonly by close person-to-person contact. Dogs, cats, and other pets do not play a role in the transmission of human lice. Lice move by crawling; they cannot hop or fly. Both over-the-counter and prescription medications are available for treatment of lice infestations. Adapted from CDC

• 

  This photomicrograph depicts a dorsal view of an adult female human head louse, Pediculus humanus var. capitis. Lice are parasitic insects that can be found on people's heads, and bodies, including the pubic area. Human lice survive by feeding on human blood. Lice found on each area of the body are different from each other. The three types of lice that live on humans are: Pediculus humanus var. capitis (head louse), Pediculus humanus var. corporis (body louse, clothes louse) and Pthirus pubis ("crab" louse, pubic louse). Only the body louse is known to spread disease. Lice infestations (pediculosis and pthiriasis) are spread most commonly by close person-to-person contact. Dogs, cats, and other pets do not play a role in the transmission of human lice. Lice move by crawling; they cannot hop or fly. Both over-the-counter and prescription medications are available for treatment of lice infestations. Adapted from CDC

• 

  This illustration depicts a dorsal view of a “crab louse”, Phthirus pubis, a member of the suborder Anoplura, or “sucking lice”. The crab louse Phthirus pubis, is not known to carry disease producing organisms. Infestations usually occur in the pubic region of humans, and may occasionally be found on other coarse body hair, such as hair on the legs, armpits, mustache, beard, eyebrows, or eyelashes. Infestations of young children are usually on the eyebrows or eyelashes. Lice found on the head are not pubic lice; they are head lice. Adapted from CDC

• 

  This illustration depicts some of the morphologic differences seen in two “sucking lice” of the Order Annoplura. The louse on the left is a “body louse”, Pediculus humanus var. corporis, and the louse on the right is a “crab” or “pubic louse”, Phthirus pubis. Note that both of these lice are wingless, and possess three pairs of claw-tipped legs, which allows them to firmly grasp the hair shafts to which they remain attached as human ectoparasitic pests. Adapted from CDC

• 

  This photograph reveals the presence of crab lice, Phthirus pubis with reddish-brown crab feces. Pubic lice are generally found in the genital area on pubic hair; but may occasionally be found on other coarse body hair, such as hair on the legs, armpit, mustache, beard, eyebrows, and eyelashes. Adapted from CDC

• 

  This is an illustration comparing the Head Louse, Pediculus humanus, with the Pubic Louse, Phthirus pubis. These insects use their hook-like appendages to grasp unto the hair shafts of their hosts in body regions unique to its species, i.e. the head louse infests the head region of its host, while the pubic louse infests its host’s pubic region. Adapted from CDC

• 

  This patient presented with an infestation of Phthirus pubis, or crab lice. A Phthirus pubis infestation has caused the erythematous lesions seen in the pubic region of this patient in response to the bites of the crab lice arthropods. Adapted from CDC

• 

  his image depicts a dorsal view of a female head louse, Pediculus humanus var. capitis. Lice are parasitic insects that can be found on people's heads, and bodies, including the pubic area. Human lice survive by feeding on human blood. Lice found on each area of the body are different from each other. The three types of lice that live on humans are: Pediculus humanus var. capitis (head louse), Pediculus humanus var. corporis (body louse, clothes louse) and Pthirus pubis ("crab" louse, pubic louse). Only the body louse is known to spread disease. Lice infestations (pediculosis and pthiriasis) are spread most commonly by close person-to-person contact. Dogs, cats, and other pets do not play a role in the transmission of human lice. Lice move by crawling; they cannot hop or fly. Both over-the-counter and prescription medications are available for treatment of lice infestations. Adapted from CDC

Scabies

• 

  Under a moderate modification, this photomicrograph revealed the histopathologic changes in a human skin sample from the site of a number of scabies burrows, due to an infestation of Sarcoptes scabiei var. hominis. Note that the scabies had burrowed into the upper layers of this patient’s skin, into the epidermis, superficial to the stratum basale, also known as the stratum germinativum. The most common signs and symptoms of scabies are intense itching (pruritus), especially at night, and a pimple-like (papular) itchy rash. The itching and rash each may affect much of the body or be limited to common sites such as the wrist, elbow, armpit, webbing between the fingers, nipple, penis, waist, belt-line, and buttocks. The rash also can include tiny blisters (vesicles) and scales. Scratching the rash can cause skin sores; sometimes these sores become infected by bacteria. Adapted from CDC

• 

  This image depicts the anterior aspect of a patient’s lower legs, either of which displaying the pathologic consequences of an infestation of Sarcoptes scabiei var. hominis, otherwise known as scabies. Of note, were the secondary severe excoriations, resulting from the patient having scratched at the primary maculopapular rash caused by the scabies bites. The most common signs and symptoms of scabies are intense itching (pruritus), especially at night, and a pimple-like (papular) itchy rash. The itching and rash each may affect much of the body or be limited to common sites such as the wrist, elbow, armpit, webbing between the fingers, nipple, penis, waist, belt-line, and buttocks. The rash also can include tiny blisters (vesicles) and scales. Scratching the rash can cause skin sores; sometimes these sores become infected by bacteria. Adapted from CDC

• 

  This close view of the genitalia of a male patient reveals the presence of erosive, inflamed lesions, which had been caused by an infestation of scabies, Sarcoptes scabiei var. hominis. The lesions are on the penile glans, and the preputial skin. The most common signs and symptoms of scabies are intense itching (pruritus), especially at night, and a pimple-like (papular) itchy rash. The itching and rash each may affect much of the body or be limited to common sites such as the wrist, elbow, armpit, webbing between the fingers, nipple, penis, waist, belt-line, and buttocks. The rash also can include tiny blisters (vesicles) and scales. Scratching the rash can cause skin sores; sometimes these sores become infected by bacteria. Adapted from CDC

• 

  This photograph depicting the dorsal surface of a human hand focused on the interdigital web space between the index and middle fingers, and revealed the presence of papules due to an infestation of the human itch mite, Sarcoptes scabiei var. hominis, otherwise commonly known as scabies. The most common signs and symptoms of scabies are intense itching (pruritus), especially at night, and a pimple-like (papular) itchy rash. The itching and rash each may affect much of the body or be limited to common sites such as the wrist, elbow, armpit, webbing between the fingers, nipple, penis, waist, belt-line, and buttocks. The rash also can include tiny blisters (vesicles) and scales. Scratching the rash can cause skin sores; sometimes these sores become infected by bacteria. Adapted from CDC

• 

  The right axillary region of this male patient exhibited a papular rash, which had been caused by an infestation of the human itch mite,Sarcoptes scabiei var. hominis, otherwise commonly known as scabies. The most common signs and symptoms of scabies are intense itching (pruritus), especially at night, and a pimple-like (papular) itchy rash. The itching and rash each may affect much of the body or be limited to common sites such as the wrist, elbow, armpit, webbing between the fingers, nipple, penis, waist, belt-line, and buttocks. The rash also can include tiny blisters (vesicles) and scales. Scratching the rash can cause skin sores; sometimes these sores become infected by bacteria. Adapted from CDC

• 

  This photomicrograph reveals a single human itch mite, Sarcoptes scabiei var. hominis, otherwise commonly known as scabies, that had burrowed itself into the epidermal layers of a skin tissue sample extracted from an unknown host. The microscopic scabies mite burrows into the upper layer of the skin where it lives and lays its eggs. The most common symptoms of scabies are intense itching and a pimple-like skin rash. The scabies mite usually is spread by direct, prolonged, skin-to-skin contact with a person who has scabies. Scabies occurs worldwide and affects people of all races and social classes. Scabies can spread rapidly under crowded conditions where close body contact is frequent. Institutions such as nursing homes, extended-care facilities, and prisons are often sites of scabies outbreaks. Adapted from CDC

• 

  This woman presented with a rash composed of pimple-like irritations on the abdomen and thorax due to canine scabies. If an animal is infested with scabies, or mange, and comes in close contact with humans, the mites can get under the skin causing itching and irritation. However, this form of scabies is mild, and the mites die in a couple of days without reproducing. Adapted from CDC

Syphilis

• Description Adapted from CDC

  Description Adapted from CDC

Trichomoniasis

• 

  This photomicrograph of a wet-mounted vaginal discharge specimen, reveals numbers of Trichomonas vaginalis protozoan parasites, leading to a diagnosis of trichomoniasis, or “trich”, which is a very common sexually transmitted disease (STD) that is caused by infection with T. vaginalis. Although symptoms of the disease vary, most women and men who have the parasite cannot tell they are infected. The parasite is passed from an infected person to an uninfected person during sex. In women, the most commonly infected part of the body is the lower genital tract (vulva, vagina, or urethra), and in men, the most commonly infected body part is the inside of the penis (urethra). During sex, the parasite is usually transmitted from a penis to a vagina, or from a vagina to a penis, but it can also be passed from a vagina to another vagina. It is not common for the parasite to infect other body parts, like the hands, mouth, or anus. It is unclear why some people with the infection get symptoms while others do not, but it probably depends on factors like the person’s age and overall health. Infected people without symptoms can still pass the infection on to others. Adapted from CDC

• 

  This patient presented with a "strawberry cervix” due to a Trichomonas vaginalis infection, or trichomoniasis. The term “strawberry cervix” is used to describe the appearance of the cervix due to the presence of T. vaginalis protozoa. The cervical mucosa reveals punctate hemorrhages along with accompanying vesicles or papules.

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Parasite Gallery

A

Acanthocephaliasis

Bolbosoma spp.

• 

  Transverse section through the body wall of Bolbosoma sp. in an intestinal biopsy specimen, stained with H&E. Image taken at 100x magnification. Cetaceans are the normal definitive hosts for Bolbosoma spp., and humans usually become infected after eating under-cooked fish which serve as paratenic hosts for the parasite.
  Adapted from CDC

• 

  Higher-magnification (200x) of the specimen in Figure 1. Identifiable in this image are the characteristic thin cuticle (CU, black arrow), syncytial epidermis (EP), longitudinal muscles (blue arrows) and eggs (green arrows).
  Adapted from CDC

• 

  Transverse section through the body wall of Bolbosoma sp. in an intestinal biopsy specimen, stained with H&E. Image taken at 100x magnification. In this image, a portion of the reproductive system is visible within the pseudocoelom.
  Adapted from CDC

Moniliformis moniliformis

Eggs of M. moniliformis

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  Eggs of M. moniliformis liberated from an adult worm that was recovered from the stool of a patient.
  Adapted from CDC

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  Egg of M. moniliformis liberated from an adult worm that was recovered from the stool of a patient.
  Adapted from CDC

Adults of M. moniliformis

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  Adult of M. moniliformis.
  Adapted from CDC

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  Adult of M. moniliformis.
  Adapted from CDC

• 

  Higher magnification of the anterior end of the specimen in Figures 1 and 2, showing a close-up of the proboscis.
  Adapted from CDC

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  Higher magnification of the anterior end of the specimen in Figures 1 and 2, showing a close-up of the proboscis.
  Adapted from CDC

Macracanthorhynchus hirudinaceous

Eggs of M. hirudinaceous

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  Eggs of M. hirudinaceous in an unstained wet mount of stool.
  Adapted from CDC

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  Egg of M. hirudinaceous in an unstained wet mount of stool.
  Adapted from CDC

• 

  Image of the same egg in Figure 2, but in a different plane of focus, showing the textured exterior.
  Adapted from CDC

Adults of M. hirudinaceous

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  Adult of M. hirudinaceous.
  Adapted from CDC

• 

  Higher magnification of the specimen in Figure 1, showing a close-up of the anterior end and the proboscis containing hooks.
  Adapted from CDC

• 

  Cross-section of the intestine of a pig, stained with H&E, showing the anterior end of an adult Macracanthorhynchus hirudinaceous embedded within the intestinal wall.
  Adapted from CDC

African trypanosomiasis (Sleeping sickness)

Trypansoma brucei ssp. in thick blood smear stained with Giemsa

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  Trypansoma brucei ssp. in a thick blood smear stained with Giemsa.
  Adapted from CDC

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  Trypansoma brucei ssp. in a thick blood smear stained with Giemsa.
  Adapted from CDC

• 

  Trypansoma brucei ssp. in a thick blood smear stained with Giemsa.
  Adapted from CDC

Trypansoma brucei ssp. in thin blood smear stained with Giemsa

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  Trypanosoma brucei ssp. in a thin blood smear stained with Giemsa.
  Adapted from CDC

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  Trypanosoma brucei ssp. in a thin blood smear stained with Giemsa.
  Adapted from CDC

• 

  Trypanosoma brucei ssp. in a thin blood smear stained with Giemsa.
  Adapted from CDC

• 

  Trypanosoma brucei ssp. in a thin blood smear stained with Giemsa.
  Adapted from CDC

Trypansoma brucei ssp. in thin blood smears stained with Wright-Giemsa

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  Trypanosoma brucei ssp. in a thin blood smear stained with Wright-Giemsa.
  Adapted from CDC

• 

  Trypanosoma brucei ssp. in a thin blood smear stained with Wright-Giemsa.
  Adapted from CDC

• 

  Trypanosoma brucei ssp. in a thin blood smear stained with Wright-Giemsa.
  Adapted from CDC

• 

  Trypanosoma brucei ssp. in a thin blood smear stained with Wright-Giemsa.
  Adapted from CDC

• 

  Trypanosoma brucei ssp. in a thin blood smear stained with Wright-Giemsa.
  Adapted from CDC

• 

  Trypanosoma brucei ssp. in a thin blood smear stained with Wright-Giemsa.
  Adapted from CDC

Trypansoma brucei ssp. in thin blood smear, beginning to divide

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  Trypanosoma brucei ssp. in a thin blood smear stained with Giemsa. The trypomastigote is beginning to divide; dividing forms are seen in African trypanosomes, but not in American trypanosomes.
  Adapted from CDC

Amebiasis

Amebiasis cysts

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  Cyst of E. histolytica/E. dispar stained with trichrome. Note the chromatoid body with blunt ends (red arrow).

Amebiasis trophozioites

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  Trophozoites of E. histolytic with ingested erythrocytes stained with trichrome. The ingested erythrocytes appear as dark inclusions. The parasite above show nuclei that have the typical small, centrally located karyosome, and thin, uniform peripheral chromatin.
  Adapted from CDC

• 

  Entamoeba histolytica trophozoites in colon tissue stained with H&E.
  Adapted from CDC

American trypanosomiasis (Chagas disease)

Trypanosoma cruzi in thick blood smears stained with Giemsa

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  Trypanosoma cruzi in thick blood smears stained with Giemsa.
  Adapted from CDC

T. cruzi in thin blood smears stained with Giemsa

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  T. cruzi trypomastigote in a thin blood smear stained with Giemsa. Note the typical C-shape of the trypomastigote that characterizes T. cruzi in fixed blood smears.
  Adapted from CDC

• 

  T. cruzi trypomastigote in a thin blood smear stained with Giemsa.
  Adapted from CDC

• 

  T. cruzi trypomastigote in a thin blood smear stained with Giemsa.
  Adapted from CDC

• 

  Higher magnification of Figure 3, T. cruzi.
  Adapted from CDC

T. cruzi in cerebrospinal fluid (CSF) stained with Giemsa

• 

  Trypanosoma cruzi trypomastigote in cerebrospinal fluid (CSF) stained with Giemsa.
  Adapted from CDC
  

T. cruzi amastigotes in heart tissue

• 

  Trypanosoma cruzi amastigotes in heart tissue. The section is stained with hematoxylin and eosin (H&E).
  Adapted from CDC
  

• 

  Trypanosoma cruzi amastigotes in heart tissue. The section is stained with H&E.
  Adapted from CDC
  

T. cruzi epimastigotes, from culture

• 

  Trypanosoma cruzi epimastigotes from culture. Note the location of the kinetoplast anterior to the nucleus.
  Adapted from CDC
  

Ancylostomiasis (Hookworm)

Ancylostoma caninum

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  Anterior end of an adult of Ancylostoma caninum, a dog parasite that has been found to produce a rare human infection known as eosinophilic enteritis.
  Adapted from CDC

Ancylostoma duodenale

• 

  Adult worm of Ancylostoma duodenal. Anterior end is depicted showing cutting teeth.
  Adapted from CDC

Necator americanus

• 

  Adult worm of Necator americanus. Anterior end showing mouth parts with cutting plates.
  Adapted from CDC

Angiostrongyliasis

Angiostrongylus cantonensis

• 

  Angiostrongylus cantonensis third stage (L3), infective larva recovered from a slug. Image captured under differential interference contrast (DIC) microscopy.
  Adapted from CDC

• 

  A. cantonensis (L3), infective larvae recovered from a slug. Image captured under DIC microscopy.
  Adapted from CDC

• 

  Higher magnification of Image 2. Note the terminal projection on the tip of the tail which is characteristic of A. cantonensis.
  Adapted from CDC

• 

  Angiostrongylus cantonensis third stage (L3), infective larva, in a wet mount, recovered from a slug. Note the terminal projection on the tip of the tail which is characteristic of A. cantonensis.
  Adapted from CDC

• 

  A. cantonensis L3, infective larvae, in wet mounts, recovered from slugs.
  Adapted from CDC

• 

  A. cantonensis L3, infective larvae, in wet mounts, recovered from slugs.
  Adapted from CDC

Angiostrongylus costaricensis

A. costaricensis Eggs

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  Angiostrongylus costaricensis eggs in intestinal tissue stained with hematoxylin and eosin (H&E).
  Adapted from CDC

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  Thin-shelled A. costaricensis eggs in intestinal tissue stained with H&E, a feature consistent with the presence of mature female worms.
  Adapted from CDC

• 

  A. costaricensis first stage (L1) larva in intestinal tissue stained with H&E
  Adapted from CDC

A. costaricensis adult female in tissue sections stained with H&E

• 

  Angiostrongylus costaricensis female worm in appendix tissue sections stained with hematoxylin and eosin (H&E). Image courtesy of Regions Hospital, St. Paul, MN.
  Adapted from CDC

• 

  Higher magnification of the specimen in Figure 1. Notice the thick, multinucleate intestine (IN) and eggs (EG) within the uterus (UT).
  Adapted from CDC

• 

  Another image from the specimen seen in Figure 1.
  Adapted from CDC

• 

  Higher magnification of the specimen in Figure 3. Shown here are the thick, multinucleate intestine (IN), reproductive tubes (RT), and lateral chords (LC).
  Adapted from CDC

Anisakiasis

Anisakis simplex

• 

  Cross-section of Anisakis sp., viewed under DIC microscopy.
  Adapted from CDC

• 

  Higher magnification of the specimen in Figure 1. Note the tall, prominent muscle cells (MU) and Y-shaped lateral chords (LC), characteristic for this genus.
  Adapted from CDC

Pseudoterranova decipiens

Pseudoterranova sp. larval worms

• 

  Anterior ends of Pseudoterranova sp. worms; images taken at 40x and 200x magnification, respectively.
  Adapted from CDC

• 

  Anterior ends of Pseudoterranova sp. worms; images taken at 40x and 200x magnification, respectively.
  Adapted from CDC

• 

  Anterior end of Pseudoterranova sp. The red arrow indicates the intestinal cecum.
  Adapted from CDC

• 

  Close-up of the intestinal cecum in the same specimen seen in Figure 3.
  Adapted from CDC

• 

  Mid-section of a Pseudoterranova sp. worm, showing the esophagus and intestine. Image taken at 40x magnification.
  Adapted from CDC

• 

  Posterior end of Pseudoterranova sp. Image taken at 200x magnification.
  Adapted from CDC

Cross sections of Pseudoterranova sp. worms Cross sections of anisakid worms.

• 

  Cross-section of Pseudoterranova sp. Note the large butterfly-shaped lateral chords (black arrows), characteristic for this genus.
  Adapted from CDC

• 

  Cross-section of Pseudoterranova sp. viewed under differential interference contrast (DIC) microscopy.
  Adapted from CDC

Ascariasis

Ascaris lumbricoides

Adult A. lumbricoides

• 

  Adult female A. lumbricoides.
  Adapted from CDC

Unfertilized egg of A. lumbricoides

• 

  Unfertilized egg of A. lumbricoides in an unstained wet mount, 200x magnification.
  Adapted from CDC

Fertilized egg of A. lumbricoides

• 

  Fertilized egg of A. lumbricoides in unstained wet mounts of stool, with embryos in the early stage of development.
  Adapted from CDC

A. lumbricoides in tissue specimen

• 

  Eggs of A. lumbricoides in an appendix biopsy, stained with H&E. This image was taken at 200x magnification.
  Adapted from CDC

B

Babesiosis

Babesia microti

• 

  Babesia microti in a thin blood smear stained with Giemsa. Babesia sp. cannot be identified to the species level by morphology alone; additional testing, such as PCR, is always recommended.
  Adapted from CDC

• 

  Babesia microti in a thin blood smear stained with Giemsa. Babesia sp. cannot be identified to the species level by morphology alone; additional testing, such as PCR, is always recommended. Note the tetrad form in this image.
  Adapted from CDC

• 

  Babesia microti in a thin blood smear stained with Giemsa. Note the intra-erythrocytic vacuolated forms indicated by the black arrows.
  Adapted from CDC

Balantidiasis

Balantidium coli

B. coli cysts

• 

  B. coli cysts in a wet mount, unstained.
  Adapted from CDC

B. coli trophozoites

• 

  B. coli trophozoite in a wet mount, 500× magnification. Note the visible cilia on the cell surface.
  Adapted from CDC

• 

  Balantidium coli trophozoites in colon tissue stained with hematoxylin and eosin (H&E) at 400x magnification.
  Adapted from CDC

Baylisascariasis

Baylisascaris procyonis

Baylisascaris procyonis eggs

• 

  Unembryonated egg of B. procyonis.
  Adapted from CDC

• 

  Embryonated eggs of B. procyonis, showing the developing larva inside.
  Adapted from CDC

Baylisascaris procyonis larvae

• 

  Larva of B. procyonis hatching from an egg.
  Adapted from CDC

• 

  Cross-sections of larvae of B. columnaris in muscle of a laboratory-infected mouse. The larval morphology and microscopic manifestations would be similar with B. procyonis in human tissue. Image taken at 400x magnification.
  Adapted from CDC

Baylisascaris procyonis larvae

• 

  Larva of B. procyonis hatching from an egg.
  Adapted from CDC

• 

  Cross-sections of larvae of B. columnaris in muscle of a laboratory-infected mouse. The larval morphology and microscopic manifestations would be similar with B. procyonis in human tissue. Image taken at 400x magnification.
  Adapted from CDC

Bed Bugs

Cimex lectularius

• 

  Two adults and one nymph (arrow) of C. lectularius, collected in a hotel in urban Georgia.
  Adapted from CDC

• 

  Close-up of one of the adults in Figure 1.
  Adapted from CDC

• 

  Higher magnification of the specimen in Figure 2. Note the reduced forewings (arrow).
  Adapted from CDC

• 

  Ventral view of the specimen in Figure 2.
  Adapted from CDC

• 

  Higher magnification of the specimen in Figure 4, showing a close-up of the typical hemipteran piercing-sucking mouthparts (arrow).
  Adapted from CDC

• 

  Nymph of C. lectularius. The blue marks represent 1 mm.
  Adapted from CDC

Bertiella

• 

  Eggs of Bertiella sp. liberated from proglottids. The proglottids were shed from a human patient who had lived for a number of years in Africa. In several of these eggs, the pyriform apparatus can be easily seen. Images courtesy of Clinipath Pathology, Perth, Australia.
  Adapted from CDC

• 

  An egg of Bertiella sp. liberated from a gravid proglottid. The arrows point to the hooklets.
  Adapted from CDC

• 

  Proglottids of Bertiella sp.
  Adapted from CDC

Bertiella struderi

• 

  Scolex of Bertiella studeri. Image courtesy of Richard Bradbury.
  Adapted from CDC

Blastocystis hominis

Blastocystis hominis cyst-like forms in wet mounts

• 

  B. hominis cyst-like forms in a wet mount, unstained.
  Adapted from CDC

• 

  B. hominis cyst-like form in a wet mount, unstained.
  Adapted from CDC

B. hominis cyst-like forms in wet mounts under differential interference contrast (DIC) microscopy

• 

  B. hominis cyst-like forms in wet mounts under differential interference contrast (DIC) microscopy.
  Adapted from CDC

• 

  B. hominis cyst-like forms in wet mounts under differential interference contrast (DIC) microscopy.
  Adapted from CDC

B. hominis cyst-like forms in wet mounts stained with iodine

• 

  B. hominis cyst-like forms in wet mounts stained in iodine.
  Adapted from CDC

• 

  B. hominis cyst-like forms in wet mounts stained in iodine.
  Adapted from CDC

B. hominis cyst-like forms stained with trichrome

• 

  B. hominis cyst-like forms stained with trichrome. The nuclei in the peripheral cytoplasmic rim are visible, staining purple.
  Adapted from CDC

• 

  B. hominis cyst-like forms stained with trichrome. The nuclei in the peripheral cytoplasmic rim are visible, staining purple.
  Adapted from CDC

• 

  Blastocystis hominis cyst-like forms stained with trichrome.
  Adapted from CDC

• 

  Blastocystis hominis cyst-like forms stained with trichrome.
  Adapted from CDC

• 

  B. hominis cyst-like forms stained with trichrome.
  Adapted from CDC

• 

  B. hominis cyst-like forms undergoing binary fission; stained with trichrome.
  Adapted from CDC

• 

  B. hominis cyst-like forms stained with trichrome.
  Adapted from CDC

C

Cercarial dermatitis (Swimmer’s itch)

Cercaria of Austrobilharzia variglandis

• 

  Cercaria of Austrobilharzia variglandis, which can cause cercarial dermatitis.
  Adapted from CDC

• 

  Cercaria of Austrobilharzia variglandis, which can cause cercarial dermatitis. Note the forked 'tail' and a pair of 'eye spots' near the anterior end.
  Adapted from CDC

Clinical manifestations of Austrobilharzia variglandis

• 

  Skin of a patient showing the inflammatory response to cercaria in the skin.
  Adapted from CDC

Chilomastix mesnili

Chilomastix mesnili trophozoites, trichrome stain

• 

  Trophozoite of C. mesnili from a stool specimen, stained with trichrome. Image taken at 1000x magnification.
  Adapted from CDC

• 

  Trophozoite of C. mesnili from a stool specimen, stained with trichrome. Image taken at 1000x magnification.
  Adapted from CDC

• 

  Trophozoite of C. mesnili from a stool specimen, stained with trichrome. Image taken at 1000x magnification.
  Adapted from CDC

• 

  Trophozoite of C. mesnili from a stool specimen, stained with trichrome. Image taken at 1000x magnification.
  Adapted from CDC

• 

  Trophozoite of C. mesnili from a stool specimen, stained with trichrome. Image taken at 1000x magnification.
  Adapted from CDC

• 

  Trophozoite of C. mesnili from a stool specimen, stained with trichrome. Image taken at 1000x magnification.
  Adapted from CDC

Chilomastix mesnili cysts, trichrome stain

• 

  Cyst of C. mesnili in a stool specimen, stained with trichrome. Image taken at 1000x magnification.
  Adapted from CDC

• 

  Cyst of C. mesnili in a stool specimen, stained with trichrome. Image taken at 1000x magnification.
  Adapted from CDC

• 

  Cyst of C. mesnili in a stool specimen, stained with trichrome. Image taken at 1000x magnification.
  Adapted from CDC

• 

  Cyst of C. mesnili in a stool specimen, stained with trichrome. Image taken at 1000x magnification.
  Adapted from CDC

• 

  Cyst of C. mesnili in a stool specimen, stained with trichrome. Image taken at 1000x magnification.
  Adapted from CDC

• 

  Cyst (lower) and trophozoite (upper) of C. mesnili in a stool specimen, stained with trichrome. Image taken at 1000x magnification.
  Adapted from CDC

Chilomastix mesnili cysts in wet mounts

• 

  Cyst of C. mesnili in a concentrated wet mount of stool, stained with iodine. Image taken at 1000x magnification.
  Adapted from CDC

• 

  Cyst of C. mesnili in a concentrated wet mount of stool, stained with iodine. Image taken at 1000x magnification.
  Adapted from CDC

Clonorchiasis

Clonorchis sinensis

Clonorchis sinensis eggs

• 

  C. sinensis egg: the small knob at the abopercular end is visible in this image.
  Adapted from CDC

• 

  C. sinensis egg. Note the operculum resting on "shoulders;" image taken at 400× magnification.
  Adapted from CDC

• 

  C. sinensis egg; images taken at 400× magnification.
  Adapted from CDC

• 

  C. sinensis egg; images taken at 400× magnification.
  Adapted from CDC

Clonorchis sinensis adults

• 

  Adult of C. sinensis.
  Adapted from CDC

• 

  Adult of C. sinensis stained with carmine. Clearly visible in this image are the oral sucker (OS), pharynx (PH), ceca (CE), acetabulum, or ventral sucker (AC), uterus (UT), vitellaria (VT) and testes (TE).
  Adapted from CDC

Clonorchis sinensis eggs

• 

  Shells of Parafossarulus manchouricus, the most common snail host of C. sinensis in endemic areas in southeast Asia. Image courtesy of the Web Atlas of Medical Parasitology and the Korean Society for Parasitology.
  Adapted from CDC

• 

  Bithynia sp., another common intermediate host of C. sinensis. Image courtesy of Michal Maňas.
  Adapted from CDC

Coenurosis

[Taenia multiceps][Taenia serialis]

Gross coenurus specimens

• 

  Large, polycephalic coenurus removed from the shoulder of a baboon (Papio sp.).
  Adapted from CDC

• 

  Close-up of a coenurus of T. multiceps removed from the eye of a patient, broken open to show multiple protoscoleces.
  Adapted from CDC

Coenuri in tissue specimens, stained with hematoxylin and eosin (H&E)

• 

  Coenurus removed from a subcutaneous nodule in the shoulder area of a patient, stained with hematoxylin and eosin (H&E). Image taken at 50x magnification. Although the species was not identified in this case, the pathology is consistent with T. serialis.
  Adapted from CDC

• 

  Higher magnification (200x) of the coenurus in Figure 1.
  Adapted from CDC

• 

  Higher magnification (200x) of the same specimen shown in Figures 1 and 2. The black arrows point to hooklets in the protoscoleces.
  Adapted from CDC

• 

  Higher magnification (200x) of the same specimen shown in Figures 1 and 2. The black arrows point to hooklets in the protoscoleces.
  Adapted from CDC

Coenurus in an eye specimens, stained with hematoxylin and eosin (H&E)

• 

  Cross-section of a human eye, showing multiple protoscoleces within a coenurus.
  Adapted from CDC

• 

  Higher magnification (200x) of the coenurus in Figure 1.
  Adapted from CDC

• 

  Higher magnification (200x) of protoscoleces shown in Figures 1 and 2.
  Adapted from CDC

• 

  Higher magnification (200x) of protoscoleces shown in Figures 1 and 2.
  Adapted from CDC

• 

  Higher magnification of the protoscolex in Figure 4, showing multiple hooklets.
  Adapted from CDC

F

Free-living amebic infections

Acanthamoeba

Acanthamoeba spp. cysts

• 

  Cysts of Acanthamoeba spp. in culture.
  Adapted from CDC

• 

  Cysts of Acanthamoeba spp. in culture.
  Adapted from CDC

• 

  Cyst of Acanthamoeba sp. from brain tissue, stained with hematoxylin and eosin (H&E).
  Adapted from CDC

• 

  Cyst of Acanthamoeba sp. from brain tissue, stained with hematoxylin and eosin (H&E).
  Adapted from CDC

• 

  Cysts of Acanthamoeba sp. (green arrows) in tissue, stained with H&E.
  Adapted from CDC

Acanthamoeba spp. trophozoites

• 

  Trophozoite of Acanthamoeba sp. from culture. Notice the slender, spine-like acanthapodia.
  Adapted from CDC

• 

  Trophozoites of Acanthamoeba sp. from culture. Notice the slender, spine-like acanthapodia.
  Adapted from CDC

• 

  Trophozoite of Acanthamoeba sp. in tissue, stained with hematoxylin and eosin (H&E).
  Adapted from CDC

• 

  Trophozoites of Acanthamoeba sp. in a corneal scraping, stained with H&E.
  Adapted from CDC

Balamuthia mandrillaris

Balamuthia mandrillaris cysts

• 

  Cysts of B. mandrillaris.
  Adapted from CDC

• 

  Close-up of one of the cysts in Figure 1.
  Adapted from CDC

• 

  Cyst of B. mandrillaris.
  Adapted from CDC

• 

  Cyst of B. mandrillaris in brain tissue, stained with hematoxylin and eosin (H&E).
  Adapted from CDC

• 

  Cyst of B. mandrillaris in brain tissue, stained with hematoxylin and eosin (H&E).
  Adapted from CDC

• 

  Cyst of B. mandrillaris in brain tissue, stained with H&E. Image courtesy of the University of Kentucky Hospital, Lexington, Kentucky.
  Adapted from CDC

• 

  Cyst of B. mandrillaris in brain tissue, stained with H&E. Image courtesy of the University of Kentucky Hospital, Lexington, Kentucky.
  Adapted from CDC

• 

  Cysts of B. mandrillaris in brain tissue, stained with H&E. Image courtesy of Cook Children’s Hospital, Fort Worth, Texas.
  Adapted from CDC

• 

  Cyst of B. mandrillaris in brain tissue, stained with H&E. Image courtesy of Cook Children’s Hospital, Fort Worth, Texas.
  Adapted from CDC

Balamuthia mandrillaris trophozoites

• 

  Trophozoite of B. mandrillaris in culture.
  Adapted from CDC

• 

  Trophozoite of B. mandrillaris in culture.
  Adapted from CDC

• 

  Trophozoite of B. mandrillaris in culture.
  Adapted from CDC

• 

  Trophozoite of B. mandrillaris in culture.
  Adapted from CDC

• 

  Several trophozoites of B. mandrillaris in brain tissue, stained with hematoxylin and eosin (H&E).
  Adapted from CDC

• 

  A single trophozoite (green arrow) of B. mandrillaris in brain tissue, stained with H&E.
  Adapted from CDC

• 

  A single trophozoite (black arrow) of B. mandrillaris in brain tissue, stained with H&E.
  Adapted from CDC

Naegleria fowleri

Naegleria fowleri cysts

• 

  Cyst of N. fowleri in culture.
  Adapted from CDC

Naegleria fowleri trophozoites

• 

  Trophozoite of N. fowleri in culture.
  Adapted from CDC

• 

  Trophozoites of N. fowleri in culture.
  Adapted from CDC

• 

  Ameboflagellate trophozoite of N. fowleri.
  Adapted from CDC

• 

  Trophozoite of N. fowleri in CSF, stained with hematoxylin and eosin (H&E).
  Adapted from CDC

• 

  Trophozoite of N. fowleri in CSF, stained with trichrome. Image courtesy of the Texas State Health Department.
  Adapted from CDC

Sappinia pedata

• 

  Four trophozoites (yellow arrows) of S. pedata in brain tissue, stained with hematoxylin and eosin (H&E). In three of the amebae, the two nuclei can easily be seen.
  Adapted from CDC

H

Hepatic capillariasis

Capillaria hepatica

Capillaria hepatica eggs

• 

  Eggs of C. hepatica in liver stained with hematoxylin and eosin (H&E).
  Adapted from CDC

• 

  Eggs of C. hepatica in liver stained with hematoxylin and eosin (H&E). The egg in this figure (1000x magnification) shows the typically striated shell and shallow polar prominences.
  Adapted from CDC

• 

  Eggs of C. hepatica in liver stained with H&E.
  Adapted from CDC

• 

  Eggs of C. hepatica in liver stained with H&E.
  Adapted from CDC

Capillaria hepatica adults

• 

  Cross section of a male C. hepatica in liver tissue, stained with hematoxylin and eosin (H&E). Note the presence of the intestine (blue arrow) and the coiled sections of the testes (black arrows).
  Adapted from CDC

• 

  Cross section of C. hepatica in liver tissue, stained with H&E. Note the presence of the intestine (blue arrow) and bacillary bands (black arrows).
  Adapted from CDC

• 

  Cross-section of C. hepatica in liver tissue, stained with H&E. Note the presence of a stichocyte (black arrow) and bacillary bands (blue arrows). Image taken at 200x magnification.
  Adapted from CDC

I

Intestinal capillariasis

Capillaria philippinensis

Capillaria philippinensis eggs

• 

  Egg of C. philippinensis in an unstained wet mount of stool.
  Adapted from CDC

• 

  Egg of C. philippinensis in an unstained wet mount of stool.
  Adapted from CDC

• 

  Egg of C. philippinensis in an unstained wet mount of stool.
  Adapted from CDC

• 

  Egg of C. philippinensis in an unstained wet mount of stool.
  Adapted from CDC

Capillaria philippinensis adults

• 

  Longitudinal section of an adult of C. philippinensis from an intestinal biopsy specimen stained with hematoxylin and eosin (H&E).
  Adapted from CDC

• 

  Longitudinal section of an adult of C. philippinensis from an intestinal biopsy specimen stained with hematoxylin and eosin (H&E).
  Adapted from CDC

• 

  Longitudinal section of an adult C. philippinensis from an intestinal biopsy specimen, stained with H&E.
  Adapted from CDC

• 

  Higher magnification of Figure 3, showing stichocytes within the adult worm.
  Adapted from CDC

• 

  Cross-section of a gravid adult female C. philippinensis from an intestinal biopsy specimen, stained with H&E. Shown in this figure are a bacillary band (blue arrow), the intestine (red arrow) and uterus containing an egg in cross-section (black arrow).
  Adapted from CDC

L

Lymphatic filariasis (Bancroftian filariasis)

Brugia malayi

• 

  Microfilaria of B. malayi in a thick blood smear, stained with Giemsa.
  Adapted from CDC

• 

  Microfilaria of B. malayi in a thin blood smear, stained with Giemsa.
  Adapted from CDC

Brugia timori

• 

  Microfilaria of B. timori in a thick blood smear from a patient from Indonesia, stained with Giemsa and captured at 500x oil magnification. Image from a specimen courtesy of Dr. Thomas C. Orihel, Tulane University, New Orleans, LA.
  Adapted from CDC

• 

  Microfilaria of B. timori in a thick blood smear from a patient from Indonesia, stained with Giemsa and captured at 500x oil magnification. Image from a specimen courtesy of Dr. Thomas C. Orihel, Tulane University, New Orleans, LA.
  Adapted from CDC

• 

  Microfilaria of B. timori in a thick blood smear from a patient from Indonesia, stained with Giemsa and captured at 500x oil magnification. Image from a specimen courtesy of Dr. Thomas C. Orihel, Tulane University, New Orleans, LA.
  Adapted from CDC

• 

  Microfilaria of B. timori in a thick blood smear from a patient from Indonesia, stained with Giemsa and captured at 500x oil magnification. Image from a specimen courtesy of Dr. Thomas C. Orihel, Tulane University, New Orleans, LA.
  Adapted from CDC

• 

  Microfilaria of B. timori in a thick blood smear from a patient from Indonesia, stained with Giemsa and captured at 500x oil magnification. Image from a specimen courtesy of Dr. Thomas C. Orihel, Tulane University, New Orleans, LA.
  Adapted from CDC

• 

  Microfilaria of B. timori in a thick blood smear from a patient from Indonesia, stained with Giemsa and captured at 500x oil magnification. Image from a specimen courtesy of Dr. Thomas C. Orihel, Tulane University, New Orleans, LA.
  Adapted from CDC

Wuchereria bancrofti

Microfilariae of Wuchereria bancrofti

• 

  Microfilaria of W. bancrofti in a thick blood smear stained with Giemsa. Image courtesy of the Oregon State Public Health Laboratory.
  Adapted from CDC

• 

  Microfilaria of W. bancrofti in a thick blood smear stained with Giemsa. Image courtesy of the Oregon State Public Health Laboratory.
  Adapted from CDC

• 

  Microfilaria of W. bancrofti in a thick blood smear, stained with Giemsa.
  Adapted from CDC

• 

  Close-up of the anterior end of the worm in Figure 3.
  Adapted from CDC

• 

  Close-up of the posterior end of the worm in Figure 3.
  Adapted from CDC

Adults of W. bancrofti

• 

  Adults of W. bancrofti. The male worm is on the left; the female is on the right.
  Adapted from CDC

M

Myiasis (Bot Flies)

Cuterebra spp.

• 

  Anterior end of a larva of a bot fly in the genus, Cuterebra.
  Adapted from CDC

• 

  Posterior end of the larva in Figure 1.
  Adapted from CDC

• 

  Adult of Cuterebra sp. Cuterebra spp. are primarily parasites of rodents and lagomorphs, although human infections are rare. Images taken from specimens courtesy of the Georgia Museum of Natural History, University of Georgia, Athens, GA.
  Adapted from CDC

• 

  Adult of Cuterebra sp. Cuterebra spp. are primarily parasites of rodents and lagomorphs, although human infections are rare. Images taken from specimens courtesy of the Georgia Museum of Natural History, University of Georgia, Athens, GA.
  Adapted from CDC

Dermatobia hominis

• 

  Four larvae of D. hominis, removed from a human host.
  Adapted from CDC

• 

  Close-up of the anterior end of one of the larvae from Figure 1, showing the mandibles.
  Adapted from CDC

• 

  Close-up of the posterior end of one of the larvae from Figure 1.
  Adapted from CDC

• 

  Anterior end of a larva of D. hominis. Image from a specimen courtesy of the Idaho State Health Department.
  Adapted from CDC

• 

  Adult of Dermatobia hominis, the human bot fly. Image taken from a specimen courtesy of the Georgia Museum of Natural History, University of Georgia, Athens, GA.
  Adapted from CDC

Oestrus ovis

• 

  First instar larva of Oestrus ovis, taken from the conjunctiva of patient in New Zealand. Image courtesy of Auckland City Hospital, Auckland, New Zealand.
  Adapted from CDC

• 

  Close-up of the anterior end of the larva in Figure 1, showing the cephalopharyngeal skeleton and mandibles.
  Adapted from CDC

• 

  Close-up of the posterior end of the larva in Figure 1.
  Adapted from CDC

• 

  First instar larva of O. ovis, collected from the eye of a patient in India presenting with conjunctivitis. Image courtesy of the L V Prasad Eye Institute, Banjara Hills, India.
  Adapted from CDC

Phormia regina

• 

  Third instar larva of P. regina, collected in the wound of a patient.
  Adapted from CDC

• 

  Close-up of the posterior spiracles of the specimen in Figure 1.
  Adapted from CDC

T

Trichinellosis (Trichinosis)

[Trichinella britovi] [Trichinella nativa] [Trichinella nelsoni] [Trichinella pseudospiralis] [Trichinella spiralis] Trichinella spp