Sandbox ID Central Nervous System
- Brain abscess
- Encephalitis
- Viruses
- Adenovirus
- B virus
- CMV
- Eastern equine encephalitis virus
- EBV
- Hendra virus
- HHV-6
- HIV
- HSV
- Influenza virus
- Japanese encephalitis virus
- JC virus
- La Crosse virus
- Measles virus
- Mumps virus
- Murray Valley encephalitis virus
- Nipah virus
- Nonpolio enteroviruses
- Poliovirus
- Powassan virus
- Rabies virus
- Rubella virus
- St. Louis encephalitis virus
- Tickborne encephalitis virus
- Vaccinia
- Venezuelan equine encephalitis virus
- VZV
- West Nile virus
- Western equine encephalitis virus
- Bacteria
- Anaplasma phagocytophilum (human granulocytotrophic ehrlichiosis)
- Bartonella bacilliformis (Oroya fever)
- Bartonella henselae (Cat scratch disease)
- Borrelia burgdorferi (Lyme disease)
- Coxiella burnetii (Q fever)
- Ehrlichia chaffeensis (human monocytotrophic ehrlichiosis)
- Listeria monocytogenes
- Mycobacterium tuberculosis
- Mycoplasma pneumoniae
- Rickettsia rickettsii (Rocky Mountain spotted fever)
- Treponema pallidum (syphilis)
- Tropheryma whipplei (Whipple's disease)
- Fungi
- Coccidioides
- Cryptococcus neoformans
- Histoplasma capsulatum:* Protozoa
- Acanthamoeba
- Balamuthia mandrillaris
- Naegleria fowleri
- Plasmodium falciparum
- Toxoplasma gondii
- Trypanosoma brucei gambiense (West African trypanosomiasis)
- Trypanosoma brucei rhodesiense (East African trypanosomiasis)
- Helminths
- Baylisascaris procyonis
- Gnathostoma
- Taenia solium (cysticercosis)
- Prion
- Human transmissible spongiform encephalopathy
- Epidural abscess
- Early neurologic disease
- Cranial nerve palsy (adult)
- Preferred regimen: Amoxicillin 500 mg 3 times orally per day for 14 (14–21) days OR Doxycycline 100 mg twice per day orally for 14 (14–21) days OR Cefuroxime axetil 500 mg twice per day orally for 14 (14–21) days.
- Alternative regimen: Azithromycin 500 mg orally per day for 7–10 days OR Clarithromycin 500 mg orally twice per day for 14–21 days(not for pregnant) OR Erythromycin 500 mg orally 4 times per day for 14–21 days.
- Cranial nerve palsy (pediatric)
- Preferred regimen: Amoxicillin 50 mg/kg per day in 3 divided doses (maximum, 500 mg per dose) orally for 14 (14–21) days OR Doxycycline Not recommended for children aged !8 years For children aged 8 years, 4 mg/kg per day in 2 divided doses (maximum, 100 mg per dose) orally for 14 (14–21) days OR Cefuroxime axetil 30 mg/kg per day in 2 divided doses (maximum, 500 mg per dose) orally for 14 (14–21) days.
- Alternative regimen: Azithromycin 500 mg orally per day for 7–10 days OR Clarithromycin 500 mg orally twice per day for 14–21 days(not for pregnant) OR Erythromycin 500 mg orally 4 times per day for 14–21 days.
- Meningitis or radiculopathy (adult)
- Preferred regimen:Ceftriaxone 2 g intravenously once per day for 14 (10–28) days.
- Alternative regimen:Cefotaxime 2 g intravenously every 8h per day for 14 (10–28) days OR Penicillin G 18–24 million U per day intravenously, divided every 4 hd for 14 (10–28) days.
- Meningitis or radiculopathy (pediatric)
- Preferred regimen:Ceftriaxone 50–75 mg/kg intravenously per day in a single dose (maximum, 2 g) for 14 (10–28) days.
- Alternative regimen:Cefotaxime 150–200 mg/kg per day intravenously in 3–4 divided doses (maximum, 6 g per day)d for 14 (10–28) days OR Penicillin G 200,000–400,000 U/kg per day divided every 4 hd (not to exceed 18–24 million U per day for 14 (10–28) days.
- Late disease
- Central or peripheral nervous system disease (adult)
- Preferred regimen:Ceftriaxone 2 g intravenously once per day for 14 (10–28) days.
- Alternative regimen:Cefotaxime 2 g intravenously every 8h per day for 14 (10–28) days OR Penicillin G 18–24 million U per day intravenously, divided every 4 hd for 14 (10–28) days.
- Central or peripheral nervous system disease (pediatric)
- Preferred regimen:Ceftriaxone 50–75 mg/kg intravenously per day in a single dose (maximum, 2 g) for 14 (10–28) days.
- Alternative regimen:Cefotaxime 150–200 mg/kg per day intravenously in 3–4 divided doses (maximum, 6 g per day)d for 14 (10–28) days OR Penicillin G 200,000–400,000 U/kg per day divided every 4 hd (not to exceed 18–24 million U per day for 14 (10–28) days.
- Meningitis