Pseudohypoparathyroidism epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mazia Fatima, MBBS [2]

Overview

All types of pseudohypoparathyroidism and associated parathyroid resistance syndromes are rare diseases.

Epidemiology and Demographics

Prevalence

  • In Japan, the prevalence of pseudohypoparathyroidism ranges from a low of 0.26 per 100,000 persons to a high of 0.42 per 100,000 persons with an average prevalence of 0.34 per 100,000 persons[1]
  • In Italy, the estimated prevalence of Pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type1b, and pseudopseudohypoparathyroidism is 0.67 per 100,000[2]

Demographics

The demographics of pseudohypoparthyroidism are as follows:[2]

Age

  • Patients with pseudohypoparthyroidism type 1a and type 1c present in the second decade with physical features of Albright's hereditary osteodystrophy
  • Neonatal screening can detect patients with severe hypoparathyroidism in severe cases

Race

  • There is no racial predilection to pseudohypoparathyroidism

Gender

  • The prevalence and incidence of pseudohypoparathyroidism is more common in women than in men

References

  1. Nakamura Y, Matsumoto T, Tamakoshi A, Kawamura T, Seino Y, Kasuga M, Yanagawa H, Ohno Y (2000). "Prevalence of idiopathic hypoparathyroidism and pseudohypoparathyroidism in Japan". J Epidemiol. 10 (1): 29–33. PMID 10695258.
  2. 2.0 2.1 "Orphanet: Pseudohypoparat".


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