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| {{CMG}}
| | #REDIRECT [[Quinapril#Overdosage]] |
| ==Overdosage topics==
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| <font size="4">[[Quinapril overdose#Manifestations|Manifestations]]</font>
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| <font size="4">[[Quinapril overdose#Lab determination|Lab determination]]</font>
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| <font size="4">[[Quinapril overdose#Physiological maneuvers|Physiological maneuvers]]</font>
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| <font size="4">[[Quinapril overdose#Hemodialysis/peritoneal dialysis|Hemodialysis/peritoneal dialysis]]</font>
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| ===Manifestations===
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| No specific information is available on the treatment of overdosage with Quinapril. The most likely clinical manifestation would be symptoms attributable to severe hypotension. ''[[Quinapril overdose#Overdosage topics|Return to top]]''
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| ===Lab determination===
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| Laboratory determinations of serum levels of Quinapril and its metabolites are not widely available, and such determinations have, in any event, no established role in the management of Quinapril overdose. ''[[Quinapril overdose#Overdosage topics|Return to top]]''
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| ===Physiological maneuvers===
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| No data are available to suggest physiological maneuvers (eg, maneuvers to change pH of the urine) that might accelerate elimination of Quinapril and its metabolites. ''[[Quinapril overdose#Overdosage topics|Return to top]]''
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| ===Hemodialysis/peritoneal dialysis===
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| Hemodialysis and peritoneal dialysis have little effect on the elimination of Quinapril and Quinaprilat. Angiotensin II could presumably serve as a specific antagonist-antidote in the setting of Quinapril overdose, but angiotensin II is essentially unavailable outside of scattered research facilities. Because the hypotensive effect of Quinapril is achieved through vasodilation and effective hypovolemia, it is reasonable to treat Quinapril overdose by infusion of normal saline solution. ''[[Quinapril overdose#Overdosage topics|Return to top]]''
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| {{FDA}}
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