Leprosy natural history, complications and prognosis: Difference between revisions

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==Complications==
==Complications==
Worldwide, 1-2 million persons are permanently disabled as a result of leprosy:<ref name="WalkerLockwood2007">{{cite journal|last1=Walker|first1=Stephen L.|last2=Lockwood|first2=Dina N.J.|title=Leprosy|journal=Clinics in Dermatology|volume=25|issue=2|year=2007|pages=165–172|issn=0738081X|doi=10.1016/j.clindermatol.2006.05.012}}</ref> The number and degree of [[complications]] will depend on how early the condition is [[diagnosed]] and [[therapy|treatment]] is started. The later a correct [[diagnosis]] is reached, greater the number and the severity of the [[complications]]. These may include:<ref name="pmid16707521">{{cite journal| author=Daniel E, Ffytche TJ, Kempen JH, Rao PS, Diener-West M, Courtright P| title=Incidence of ocular complications in patients with multibacillary leprosy after completion of a 2 year course of multidrug therapy. | journal=Br J Ophthalmol | year= 2006 | volume= 90 | issue= 8 | pages= 949-54 | pmid=16707521 | doi=10.1136/bjo.2006.094870 | pmc=PMC1857220 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16707521  }} </ref>
Worldwide, 1-2 million persons are permanently disabled as a result of leprosy:<ref name="WalkerLockwood2007">{{cite journal|last1=Walker|first1=Stephen L.|last2=Lockwood|first2=Dina N.J.|title=Leprosy|journal=Clinics in Dermatology|volume=25|issue=2|year=2007|pages=165–172|issn=0738081X|doi=10.1016/j.clindermatol.2006.05.012}}</ref> The number and degree of [[complications]] will depend on how early the condition is [[diagnosed]] and [[therapy|treatment]] is started. The later a correct [[diagnosis]] is reached, greater the number and the severity of the [[complications]]. These may include:<ref name="pmid16707521">{{cite journal| author=Daniel E, Ffytche TJ, Kempen JH, Rao PS, Diener-West M, Courtright P| title=Incidence of ocular complications in patients with multibacillary leprosy after completion of a 2 year course of multidrug therapy. | journal=Br J Ophthalmol | year= 2006 | volume= 90 | issue= 8 | pages= 949-54 | pmid=16707521 | doi=10.1136/bjo.2006.094870 | pmc=PMC1857220 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16707521  }} </ref><ref name=CDC>{{cite web | title = P
Hansen's Disease (Leprosy) | url = http://www.cdc.gov/leprosy/symptoms/index.html }}</ref>
* Cosmetic disfigurement with [[skin ulceration]] and [[scars]].
* Cosmetic disfigurement with [[skin ulceration]] and [[scars]].



Revision as of 22:52, 4 July 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]

Natural History

Complications

Worldwide, 1-2 million persons are permanently disabled as a result of leprosy:[1] The number and degree of complications will depend on how early the condition is diagnosed and treatment is started. The later a correct diagnosis is reached, greater the number and the severity of the complications. These may include:[2][3]

Prognosis

Early recognition is important. Early treatment limits damage by the disease, renders the person noninfectious, and allows for a normal lifestyle.

References

  1. Walker, Stephen L.; Lockwood, Dina N.J. (2007). "Leprosy". Clinics in Dermatology. 25 (2): 165–172. doi:10.1016/j.clindermatol.2006.05.012. ISSN 0738-081X.
  2. Daniel E, Ffytche TJ, Kempen JH, Rao PS, Diener-West M, Courtright P (2006). "Incidence of ocular complications in patients with multibacillary leprosy after completion of a 2 year course of multidrug therapy". Br J Ophthalmol. 90 (8): 949–54. doi:10.1136/bjo.2006.094870. PMC 1857220. PMID 16707521.
  3. "P Hansen's Disease (Leprosy)". line feed character in |title= at position 2 (help)


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