Sandbox:Sahar

Lipomatous tumor	Age of onset	Gender preponderance	Location	Clinical features	Pathologic appearance	Other features	Pathologic view
Angiolipoma	Second and third decades of life	Female < male	More commonly seen in forearm May also affect trunk and upper arm	Subcutaneous nodule Tender to palpation Less than 2 cm	Encapsulated, yellow nodules with a reddish tinge A combination of fatty tissue and vascular channels Fibrin thrombi is present in vascular channels (characteristic finding)	Benign
Myolipoma	Fifth and sixth decades of life	Female > male	More commonly seen in retroperitoneum, abdomen, pelvis, inguinal region, or abdominal wall May also affect extremities	Subcutaneous mass which may also engage superficial muscular fascia Size differs depending on the location	Partially encapsulated mass with partially yellow-white cut surface A combination of mature adipocytes and sheets of well-differentiated smooth muscle No nuclear atypia Sieve-like appearance at low magnification (due to interspersed location of smooth muscle component)	Benign It is usually large and located in the deep soft tissues
Myelolipoma	Fifth decade of life	Female = male	More commonly seen in adrenal glands Other possible locations include: thoracic,  retroperitoneum  and presacral region,  mediastinum,  liver,  and bone	Usually asymptomatic May cause abdominal pain, nausea, and constipation (depending on the location and size) Uncommonly, may cause retro-peritoneal hemorrhage 3 to 7 cm	A combination of bone marrow elements and adipose tissue in varying proportions May show myxoid changes	Well-circumscribed radiolucent mass in radiologic imaging May have hromonal activity
Spindle Cell/Pleomorphic Lipoma	Fifth to seventh decades of life	Female < male	More commonly seen in posterior neck, shoulder, and back It is also reported in oral cavity	Subcutaneous nodule with firm consistency Slowly growing and painless Mostly between 3 to 5 cm	Similar to ordinary lipoma A combination of mature fat cells and spindle cell or pleomorphic elements Lipomatous component may vary in amount	Immunohistochemically positive for CD34 Benign
Chondroid Lipoma	Third or fourth decade of life	Female > male	More commonly seen in limbs and limb girdles May also involve trunk, and the head and neck region, particularly the oral cavity	Slowly growing painless mass Sizes ranges from 1 to 11 cm	Encapsulated tumor with a yellow, white, or pink-tan cut surface A combination of mature adipocytes in association with nests of vacuolated cells in a myxochondroid or hyalinized fibrous background	Heterogeneous soft tissue mass in radiologic imaging Benign
Hibernoma	Third decade of life	Female = male	Most commonly seen in thigh May also affect shoulder, back, neck, chest, arm, and abdominal cavity/retroperitoneum	Slowly growing, painless, subcutaneous mass Affects intramuscular in 10% of the cases Size varies between 5 to 15 cm	Well-defined, soft, and mobile mass A combination of vacuolated granular eosinophilic cells with abundant mithochondria and high vascular content	Immunohistochemically positive for S-100 Benign
Lipomas of Tendon Sheaths and Joints	Second and third decades of life
Intramuscular and Intermuscular Lipomas
Neural Fibrolipoma

Example #1

The patient presented with S.O.B. one year after hysterectomy for a leiomyomatous uterus.

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  CT in Intravenous leiomyomatosis

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