Chondrosarcoma staging: Difference between revisions

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==Overview==
==Overview==
On gross pathology, greyish-white lobulated mass, [[necrosis]], [[calcification]], and mucoid degeneration are characteristic findings of chondrosarcoma. On microscopic histopathological analysis abnormal [[cartilage]], increased cellularity, and nuclear atypia are characteristic findings of chondrosarcoma. Chondrosarcoma may be divided into three grades based on cancer cells morphology under microscope and growth rate of [[tumor]].
Chondrosarcoma is staged based on enniking staging system for malignant bone tumor based on histological and radiological findings.
==Staging==
*Chondrosarcoma is staged based on enniking staging system.
 
===Enneking (MSTS) Staging System===
*The Enneking surgical staging system (also known as the MSTS system) for malignant [[Musculoskeletal system|musculoskeletal]] [[Tumor|tumors]] based on [[radiographic]] characteristics of the tumor host margin.<ref name="pmid20333492">{{cite journal| author=Jawad MU, Scully SP| title=In brief: classifications in brief: enneking classification: benign and malignant tumors of the musculoskeletal system. | journal=Clin Orthop Relat Res | year= 2010 | volume= 468 | issue= 7 | pages= 2000-2 | pmid=20333492 | doi=10.1007/s11999-010-1315-7 | pmc=2882012 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20333492  }} </ref><ref>{{cite book | last = Peabody | first = Terrance | title = Orthopaedic oncology : primary and metastatic tumors of the skeletal system | publisher = Springer | location = Cham | year = 2014 | isbn = 9783319073224 }}</ref>
*It is widely accepted and routinely used staging system.
 
{| style="border: 0px; font-size: 90%; margin: 3px; width: 1000px" align="center"
| valign="top" |
|-
! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Stages}}
! style="background: #4479BA; width: 300px;" |{{fontcolor|#FFF|Grade}}
! style="background: #4479BA; width: 300px;" |{{fontcolor|#FFF|Site}}
! style="background: #4479BA; width: 300px;" |{{fontcolor|#FFF|Metastasis}}
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" |IA
| style="padding: 5px 5px; background: #F5F5F5; font-weight: bold; text-align:center;" | G1: Low grade
| style="padding: 5px 5px; background: #F5F5F5; font-weight: bold; text-align:center;" | T1: Intracompartmental
| style="padding: 5px 5px; background: #F5F5F5; font-weight: bold; text-align:center;" | M0: No metastasis
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" |IB
| style="padding: 5px 5px; background: #F5F5F5; font-weight: bold; text-align:center;" | G1: Low grade
| style="padding: 5px 5px; background: #F5F5F5; font-weight: bold; text-align:center;" | T2: Extracompartmental
| style="padding: 5px 5px; background: #F5F5F5; font-weight: bold; text-align:center;" | M0: No metastasis
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" |IIA
| style="padding: 5px 5px; background: #F5F5F5; font-weight: bold; text-align:center;" | G2: High grade
| style="padding: 5px 5px; background: #F5F5F5; font-weight: bold; text-align:center;" | T1: Intracompartmental
| style="padding: 5px 5px; background: #F5F5F5; font-weight: bold; text-align:center;" | M0: No metastasis
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" |IIB
| style="padding: 5px 5px; background: #F5F5F5; font-weight: bold; text-align:center;" | G2: High grade
| style="padding: 5px 5px; background: #F5F5F5; font-weight: bold; text-align:center;" | T2: Extracompartmental
| style="padding: 5px 5px; background: #F5F5F5; font-weight: bold; text-align:center;" | M0: No metastasis
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" |III
| style="padding: 5px 5px; background: #F5F5F5; font-weight: bold; text-align:center;" | G1 or G2
| style="padding: 5px 5px; background: #F5F5F5; font-weight: bold; text-align:center;" | T1 or T2
| style="padding: 5px 5px; background: #F5F5F5; font-weight: bold; text-align:center;" | M1: Regional or distant metastasis
|}


==Pathophysiology==


==References==
==References==

Revision as of 20:14, 22 January 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rohan A. Bhimani, M.B.B.S., D.N.B., M.Ch.[2]


Overview

Chondrosarcoma is staged based on enniking staging system for malignant bone tumor based on histological and radiological findings.

Staging

  • Chondrosarcoma is staged based on enniking staging system.

Enneking (MSTS) Staging System

  • The Enneking surgical staging system (also known as the MSTS system) for malignant musculoskeletal tumors based on radiographic characteristics of the tumor host margin.[1][2]
  • It is widely accepted and routinely used staging system.
Stages Grade Site Metastasis
IA G1: Low grade T1: Intracompartmental M0: No metastasis
IB G1: Low grade T2: Extracompartmental M0: No metastasis
IIA G2: High grade T1: Intracompartmental M0: No metastasis
IIB G2: High grade T2: Extracompartmental M0: No metastasis
III G1 or G2 T1 or T2 M1: Regional or distant metastasis


References

  1. Jawad MU, Scully SP (2010). "In brief: classifications in brief: enneking classification: benign and malignant tumors of the musculoskeletal system". Clin Orthop Relat Res. 468 (7): 2000–2. doi:10.1007/s11999-010-1315-7. PMC 2882012. PMID 20333492.
  2. Peabody, Terrance (2014). Orthopaedic oncology : primary and metastatic tumors of the skeletal system. Cham: Springer. ISBN 9783319073224.

References


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