Hairy cell leukemia diagnotic study of choice: Difference between revisions
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[[Peripheral blood smear|Peripheral blood smears]] is one of the gold standard test for the diagnosis of [[hairy cell leukemia]]. | [[Peripheral blood smear|Peripheral blood smears]] is one of the gold standard test for the diagnosis of [[hairy cell leukemia]]. | ||
The following result of [[Peripheral blood smear|peripheral blood smears]] is confirmatory of [[hairy cell leukemia]]: | The following result of [[Peripheral blood smear|peripheral blood smears]] is confirmatory of [[hairy cell leukemia]]:<ref name="Cazzola2016">{{cite journal|last1=Cazzola|first1=M.|title=Introduction to a review series: the 2016 revision of the WHO classification of tumors of hematopoietic and lymphoid tissues|journal=Blood|volume=127|issue=20|year=2016|pages=2361–2364|issn=0006-4971|doi=10.1182/blood-2016-03-657379}}</ref> | ||
* Oval [[nuclei]] and abundant [[cytoplasm]] with "hairy" projections | * Oval [[nuclei]] and abundant [[cytoplasm]] with "hairy" projections | ||
* Fried egg appearance | * Fried egg appearance | ||
Revision as of 17:23, 20 November 2018
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Overview
Peripheral blood smears are the gold standard test for the diagnosis of hairy cell leukemia.
Diagnostic Study of Choice
Study of choice
Peripheral blood smear:
Peripheral blood smears is one of the gold standard test for the diagnosis of hairy cell leukemia.
The following result of peripheral blood smears is confirmatory of hairy cell leukemia:[1]
- Oval nuclei and abundant cytoplasm with "hairy" projections
- Fried egg appearance
- Loose chromatin
- Mast cells numbers elevation
- Extravasated red cells are positive in peripheral blood smear of hairy cell leukemia patients
References
- ↑ Cazzola, M. (2016). "Introduction to a review series: the 2016 revision of the WHO classification of tumors of hematopoietic and lymphoid tissues". Blood. 127 (20): 2361–2364. doi:10.1182/blood-2016-03-657379. ISSN 0006-4971.