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{{familytree | | | | |D01| | | | D02| | | | D03 |D01='''Squamous cell carcinoma'''|D02='''Neuroendocrine carcinoma'''|D03='''Adenocarcinoma and poorly differntiated carcinoma'''}}
{{familytree | | | | |D01| | | | D02| | | | D03 |D01='''Squamous cell carcinoma'''|D02='''Neuroendocrine carcinoma'''|D03='''Adenocarcinoma and poorly differntiated carcinoma'''}}
{{familytree | | | | | |!| | | | | |!| | | | | |!| | | | }}
{{familytree | | | | | |!| | | | | |!| | | | | |!| | | | }}
{{familytree | | | | | |!| | | | |boxstyle=text-align: left;|E01| | | | |!| |E01=• Octreoscan<br> • Plasma chromogranin A}}
{{familytree | | | | | |!| | | | |boxstyle=text-align: left;|E01| | | | |!| |E01=• Octreoscan<br>• Plasma chromogranin A}}
{{familytree | | | | |F01| | | | | | | | | | F02 | |F01=Additional tests specific to location of metastasis|F02=Gender specific tests}}
{{familytree | | | | |F01| | | | | | | | | | F02 | |F01=Additional tests specific to location of metastasis|F02=Gender specific tests}}
{{familytree | | | | | |!| | | | | | | | | | | |!|| | }}
{{familytree | | | | | |!| | | | | | | | | | | |!|| | }}
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{{familytree | J01 | | J02 | | J03 | | J04 | | J05 | | J06 | | J07 | | J08 | | J09 |J01=Midline and/or mediastinal lymphadenopathy|J02=Cervical and/or supraclavicular lymphadenopathy|J03=Axillary lymphadenopathy|J04=Liver metastasis|J05=Lung metastasis|J06=Bone metastasis|J07=Single metastasis|J08=Pleural effusion|J09=Periotneal effusion}}
{{familytree | J01 | | J02 | | J03 | | J04 | | J05 | | J06 | | J07 | | J08 | | J09 |J01=Midline and/or mediastinal lymphadenopathy|J02=Cervical and/or supraclavicular lymphadenopathy|J03=Axillary lymphadenopathy|J04=Liver metastasis|J05=Lung metastasis|J06=Bone metastasis|J07=Single metastasis|J08=Pleural effusion|J09=Periotneal effusion}}
{{familytree | |!| | | |!| | | |!| | | |!| | | |!| | | |!| | | |!| | | |!| | | |!| |}}
{{familytree | |!| | | |!| | | |!| | | |!| | | |!| | | |!| | | |!| | | |!| | | |!| |}}
{{familytree |boxstyle=text-align: left;| K01 | | K02 | | K03 | | K04 | | K05 | | K06 | | K07 | | K08 | | K09 |K01=• Testicular ultrasound<br>• Chest and abdominal CT scan|K02=• Testicular ultrasound<br>• Head and neck CT scan<br>• Panendoscopy<br>• EBV testing (to rule out undifferentiated nasopharyngeal carcinoma)|K03=Women:<br>• Breast ultrasound<br>• Breast MRI|K04=Women:<br>• aFP assay (if undifferntiated carcinoma)<br>• Colposcopy|K05=Women:<br>• BHCG<br>Men:<br>• Testicular ultrasound<br>• Chest and abdominal CT scan|K06=• Bone scintigraphy<br>• Xrays of painful areas|K07=• Full body CT scan<br>• Bone scintigraphy|K08=• Chest CT scan|K09=Women:<br>• Abdominal and pelvic CT scan}}
{{familytree/end}}
{{familytree/end}}

Revision as of 21:36, 10 October 2018

 
 
 
 
 
 
 
 
 
 
Tumor of unknown primary origin
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
• Full medical history and physical exam
• Basic blood and bichemical analysis
• CT scan of chest, abdomen, and pelvis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Histopathologic examination
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Squamous cell carcinoma
 
 
 
Neuroendocrine carcinoma
 
 
 
Adenocarcinoma and poorly differntiated carcinoma
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
• Octreoscan
• Plasma chromogranin A
 
 
 
 
 
 
 
 
 
 
 
Additional tests specific to location of metastasis
 
 
 
 
 
 
 
 
 
Gender specific tests
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Cervical lymphadenopathy
 
Inguinal lymphadenopathy
 
Bone metastasis
 
 
 
Male
 
Female
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
• Panendoscopy
• CT scan of head and neck
• Diagnostic bilateral amygdalectomy
 
• Complete clinical examination of external genital organs
• Pelvic CT scan or ultrasound
 
• Anoscopy
• Colposcopy (if female)
• Complete clinical examination of head and neck
• Panendoscopy
• Bone scintigraphy
• Xrays of painful areas
 
 
 
• PSA
• aFP
• BHCG
 
• Mammography
• Pelvic ultrasound or CT scan
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Additional tests specific to location of metastasis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Midline and/or mediastinal lymphadenopathy
 
Cervical and/or supraclavicular lymphadenopathy
 
Axillary lymphadenopathy
 
Liver metastasis
 
Lung metastasis
 
Bone metastasis
 
Single metastasis
 
Pleural effusion
 
Periotneal effusion
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
• Testicular ultrasound
• Chest and abdominal CT scan
 
• Testicular ultrasound
• Head and neck CT scan
• Panendoscopy
• EBV testing (to rule out undifferentiated nasopharyngeal carcinoma)
 
Women:
• Breast ultrasound
• Breast MRI
 
Women:
• aFP assay (if undifferntiated carcinoma)
• Colposcopy
 
Women:
• BHCG
Men:
• Testicular ultrasound
• Chest and abdominal CT scan
 
• Bone scintigraphy
• Xrays of painful areas
 
• Full body CT scan
• Bone scintigraphy
 
• Chest CT scan
 
Women:
• Abdominal and pelvic CT scan