Seronegative spondyloarthritis: Difference between revisions
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==Classification Criteria== | ==Classification Criteria== | ||
The Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (axial SpA) include: | |||
*Patient with back pain ≥ 3 months and age of onset <45 years should fulfill either of the two criteria: | |||
*# Sacroiliitis on imaging<sup>'''*'''</sup> plus ≥ 1 feature of SpA<sup>'''**'''</sup> | |||
*# HLA-B27 plus ≥ 2 feature of SpA<sup>'''**'''</sup> | |||
:::<sup>'''*'''</sup>'''Sacroiliitis on imaging:''' | |||
:::*Active (acute) inflammation on MRI highly suggestive of sacroiliitis associated with SpA | |||
:OR | |||
:::*Definite radiographic sacroillitis accorging to modified New York criteria | |||
:::<sup>'''**'''</sup>'''SpA features:''' | |||
:::*Inflammatroy back pain | |||
:::*Arthritis | |||
:::*Enthesotos (heel) | |||
:::*Uveitis | |||
:::*Dactylitis | |||
:::*Psoriasis | |||
:::*Crohn's disease or ulcerative colitis | |||
:::*Good response to NSAIDs | |||
:::*Family history for SpA | |||
:::*HLA-B27 | |||
:::*Elevated CRP | |||
==ASAS classification criteria for peripheral spondyloarthritis== | |||
==Differential== | ==Differential== |
Revision as of 16:21, 9 April 2018
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
"Seronegative" refers to the fact that these diseases are negative for Rheumatoid factor and CCP in the serum.
Classsiication
Algorithm showing classification of seronegative spondyloarthritis[1]
Seronegative Spondyloarthritis (SpA) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Axial SpA including Ankylosing spondylitis | Peripheral SpA | Psoriatic arthritis | Reactive arthritis | Inflammatory bowel disease related arthritis | Juvenile spondyloarthritis | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Classification Criteria
The Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (axial SpA) include:
- Patient with back pain ≥ 3 months and age of onset <45 years should fulfill either of the two criteria:
- Sacroiliitis on imaging* plus ≥ 1 feature of SpA**
- HLA-B27 plus ≥ 2 feature of SpA**
- *Sacroiliitis on imaging:
- Active (acute) inflammation on MRI highly suggestive of sacroiliitis associated with SpA
- *Sacroiliitis on imaging:
- OR
- Definite radiographic sacroillitis accorging to modified New York criteria
- **SpA features:
- Inflammatroy back pain
- Arthritis
- Enthesotos (heel)
- Uveitis
- Dactylitis
- Psoriasis
- Crohn's disease or ulcerative colitis
- Good response to NSAIDs
- Family history for SpA
- HLA-B27
- Elevated CRP
ASAS classification criteria for peripheral spondyloarthritis
Differential
Diagnosis
These diseases has following conditions in common:
- They are in relation to HLA-B27
- sacroiliitis and spondylitis are present in them.
- familial aggregation occurs
- Overlap is likely in them
- rheumatoid factor is not present
References
- ↑ Dougados M, Baeten D (2011). "Spondyloarthritis". Lancet. 377 (9783): 2127–37. doi:10.1016/S0140-6736(11)60071-8. PMID 21684383.