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== Idiopathic inflammatory myopathies ==
== Idiopathic inflammatory myopathies ==
* There are several types of idiopathic inflammatory myopathies which include:<ref name="pmid29595280">{{cite journal |vauthors=Vencovský J |title=[Idiopathic inflammatory myopathies] |language=Czech |journal=Vnitr Lek |volume=64 |issue=2 |pages=155–163 |date=2018 |pmid=29595280 |doi= |url=}}</ref><ref name="pmid29579414">{{cite journal |vauthors=Adler BL, Christopher-Stine L |title=Triggers of inflammatory myopathy: insights into pathogenesis |journal=Discov Med |volume=25 |issue=136 |pages=75–83 |date=February 2018 |pmid=29579414 |doi= |url=}}</ref><ref name="pmid25182203">{{cite journal |vauthors=Bodoki L, Nagy-Vincze M, Griger Z, Betteridge Z, Szöllősi L, Dankó K |title=Four dermatomyositis-specific autoantibodies-anti-TIF1γ, anti-NXP2, anti-SAE and anti-MDA5-in adult and juvenile patients with idiopathic inflammatory myopathies in a Hungarian cohort |journal=Autoimmun Rev |volume=13 |issue=12 |pages=1211–9 |date=December 2014 |pmid=25182203 |doi=10.1016/j.autrev.2014.08.011 |url=}}</ref><ref name="BohanPeter1975">{{cite journal|last1=Bohan|first1=Anthony|last2=Peter|first2=James B.|title=Polymyositis and Dermatomyositis|journal=New England Journal of Medicine|volume=292|issue=8|year=1975|pages=403–407|issn=0028-4793|doi=10.1056/NEJM197502202920807}}</ref><ref name="pmid26429706">{{cite journal |vauthors=Tiniakou E, Mammen AL |title=Idiopathic Inflammatory Myopathies and Malignancy: a Comprehensive Review |journal=Clin Rev Allergy Immunol |volume=52 |issue=1 |pages=20–33 |date=February 2017 |pmid=26429706 |doi=10.1007/s12016-015-8511-x |url=}}</ref><ref name="pmid24305450">{{cite journal |vauthors=Amato AA, Greenberg SA |title=Inflammatory myopathies |journal=Continuum (Minneap Minn) |volume=19 |issue=6 Muscle Disease |pages=1615–33 |date=December 2013 |pmid=24305450 |doi=10.1212/01.CON.0000440662.26427.bd |url=}}</ref><ref name="pmid19349710">{{cite journal |vauthors=Dimachkie MM, Barohn RJ |title=Idiopathic inflammatory myopathies |journal=Front Neurol Neurosci |volume=26 |issue= |pages=126–46 |date=2009 |pmid=19349710 |doi=10.1159/000212374 |url=}}</ref><ref name="pmid18351525">{{cite journal |vauthors=Greenberg SA |title=Inflammatory myopathies: evaluation and management |journal=Semin Neurol |volume=28 |issue=2 |pages=241–9 |date=April 2008 |pmid=18351525 |doi=10.1055/s-2008-1062267 |url=}}</ref><ref name="pmid21444016">{{cite journal |vauthors=Khan S, Christopher-Stine L |title=Polymyositis, dermatomyositis, and autoimmune necrotizing myopathy: clinical features |journal=Rheum. Dis. Clin. North Am. |volume=37 |issue=2 |pages=143–58, v |date=May 2011 |pmid=21444016 |doi=10.1016/j.rdc.2011.01.001 |url=}}</ref>
* There are several types of idiopathic inflammatory myopathies which include:<ref name="pmid29595280">{{cite journal |vauthors=Vencovský J |title=[Idiopathic inflammatory myopathies] |language=Czech |journal=Vnitr Lek |volume=64 |issue=2 |pages=155–163 |date=2018 |pmid=29595280 |doi= |url=}}</ref><ref name="pmid29579414">{{cite journal |vauthors=Adler BL, Christopher-Stine L |title=Triggers of inflammatory myopathy: insights into pathogenesis |journal=Discov Med |volume=25 |issue=136 |pages=75–83 |date=February 2018 |pmid=29579414 |doi= |url=}}</ref><ref name="pmid25182203">{{cite journal |vauthors=Bodoki L, Nagy-Vincze M, Griger Z, Betteridge Z, Szöllősi L, Dankó K |title=Four dermatomyositis-specific autoantibodies-anti-TIF1γ, anti-NXP2, anti-SAE and anti-MDA5-in adult and juvenile patients with idiopathic inflammatory myopathies in a Hungarian cohort |journal=Autoimmun Rev |volume=13 |issue=12 |pages=1211–9 |date=December 2014 |pmid=25182203 |doi=10.1016/j.autrev.2014.08.011 |url=}}</ref><ref name="BohanPeter1975">{{cite journal|last1=Bohan|first1=Anthony|last2=Peter|first2=James B.|title=Polymyositis and Dermatomyositis|journal=New England Journal of Medicine|volume=292|issue=8|year=1975|pages=403–407|issn=0028-4793|doi=10.1056/NEJM197502202920807}}</ref><ref name="pmid26429706">{{cite journal |vauthors=Tiniakou E, Mammen AL |title=Idiopathic Inflammatory Myopathies and Malignancy: a Comprehensive Review |journal=Clin Rev Allergy Immunol |volume=52 |issue=1 |pages=20–33 |date=February 2017 |pmid=26429706 |doi=10.1007/s12016-015-8511-x |url=}}</ref><ref name="pmid24305450">{{cite journal |vauthors=Amato AA, Greenberg SA |title=Inflammatory myopathies |journal=Continuum (Minneap Minn) |volume=19 |issue=6 Muscle Disease |pages=1615–33 |date=December 2013 |pmid=24305450 |doi=10.1212/01.CON.0000440662.26427.bd |url=}}</ref><ref name="pmid19349710">{{cite journal |vauthors=Dimachkie MM, Barohn RJ |title=Idiopathic inflammatory myopathies |journal=Front Neurol Neurosci |volume=26 |issue= |pages=126–46 |date=2009 |pmid=19349710 |doi=10.1159/000212374 |url=}}</ref><ref name="pmid18351525">{{cite journal |vauthors=Greenberg SA |title=Inflammatory myopathies: evaluation and management |journal=Semin Neurol |volume=28 |issue=2 |pages=241–9 |date=April 2008 |pmid=18351525 |doi=10.1055/s-2008-1062267 |url=}}</ref><ref name="pmid21444016">{{cite journal |vauthors=Khan S, Christopher-Stine L |title=Polymyositis, dermatomyositis, and autoimmune necrotizing myopathy: clinical features |journal=Rheum. Dis. Clin. North Am. |volume=37 |issue=2 |pages=143–58, v |date=May 2011 |pmid=21444016 |doi=10.1016/j.rdc.2011.01.001 |url=}}</ref><ref name="pmid21411269">{{cite journal |vauthors=Dalakas MC |title=Pathophysiology of inflammatory and autoimmune myopathies |journal=Presse Med |volume=40 |issue=4 Pt 2 |pages=e237–47 |date=April 2011 |pmid=21411269 |doi=10.1016/j.lpm.2011.01.005 |url=}}</ref><ref name="Hilton-Jones2011">{{cite journal|last1=Hilton-Jones|first1=David|title=Observations on the classification of the inflammatory myopathies|journal=La Presse Médicale|volume=40|issue=4|year=2011|pages=e199–e208|issn=07554982|doi=10.1016/j.lpm.2010.10.035}}</ref><ref name="BenvenisteLéger2011">{{cite journal|last1=Benveniste|first1=Olivier|last2=Léger|first2=Jean-Marc|title=Inflammatory or necrotizing myopathies, myositides and other acquired myopathies, new insight in 2011|journal=La Presse Médicale|volume=40|issue=4|year=2011|pages=e197–e198|issn=07554982|doi=10.1016/j.lpm.2011.02.002}}</ref>
* Common features are:
* Common features are:
** Symmetrical, proximal muscle weakness
** Symmetrical, proximal muscle weakness

Revision as of 18:22, 5 April 2018

Idiopathic inflammatory myopathies 

  • There are several types of idiopathic inflammatory myopathies which include:[1][2][3][4][5][6][7][8][9][10][11][12]
  • Common features are:
    • Symmetrical, proximal muscle weakness
    • Elevated muscle enzymes
    • Elevated myoglobin
    • Increased risk of malignancies
    • Abnormal electrical properties of muscle fibers detected by EMG
    • Positive autoantibodies against nuclear or cytoplasmic antigens in their serum
    • Treatment with glucocorticoids and immunosuppressive drugs
Inflammatory myopathy 
Polymyositis and dermatomyositis
Inclusion body myositis[13]
Immune mediated necrotizing myopathy
Juvenile myositis
Cancer associated myositis
Myositis in overlap syndromes

References

  1. Vencovský J (2018). "[Idiopathic inflammatory myopathies]". Vnitr Lek (in Czech). 64 (2): 155–163. PMID 29595280.
  2. Adler BL, Christopher-Stine L (February 2018). "Triggers of inflammatory myopathy: insights into pathogenesis". Discov Med. 25 (136): 75–83. PMID 29579414.
  3. Bodoki L, Nagy-Vincze M, Griger Z, Betteridge Z, Szöllősi L, Dankó K (December 2014). "Four dermatomyositis-specific autoantibodies-anti-TIF1γ, anti-NXP2, anti-SAE and anti-MDA5-in adult and juvenile patients with idiopathic inflammatory myopathies in a Hungarian cohort". Autoimmun Rev. 13 (12): 1211–9. doi:10.1016/j.autrev.2014.08.011. PMID 25182203.
  4. Bohan, Anthony; Peter, James B. (1975). "Polymyositis and Dermatomyositis". New England Journal of Medicine. 292 (8): 403–407. doi:10.1056/NEJM197502202920807. ISSN 0028-4793.
  5. Tiniakou E, Mammen AL (February 2017). "Idiopathic Inflammatory Myopathies and Malignancy: a Comprehensive Review". Clin Rev Allergy Immunol. 52 (1): 20–33. doi:10.1007/s12016-015-8511-x. PMID 26429706.
  6. Amato AA, Greenberg SA (December 2013). "Inflammatory myopathies". Continuum (Minneap Minn). 19 (6 Muscle Disease): 1615–33. doi:10.1212/01.CON.0000440662.26427.bd. PMID 24305450.
  7. Dimachkie MM, Barohn RJ (2009). "Idiopathic inflammatory myopathies". Front Neurol Neurosci. 26: 126–46. doi:10.1159/000212374. PMID 19349710.
  8. Greenberg SA (April 2008). "Inflammatory myopathies: evaluation and management". Semin Neurol. 28 (2): 241–9. doi:10.1055/s-2008-1062267. PMID 18351525.
  9. Khan S, Christopher-Stine L (May 2011). "Polymyositis, dermatomyositis, and autoimmune necrotizing myopathy: clinical features". Rheum. Dis. Clin. North Am. 37 (2): 143–58, v. doi:10.1016/j.rdc.2011.01.001. PMID 21444016.
  10. Dalakas MC (April 2011). "Pathophysiology of inflammatory and autoimmune myopathies". Presse Med. 40 (4 Pt 2): e237–47. doi:10.1016/j.lpm.2011.01.005. PMID 21411269.
  11. Hilton-Jones, David (2011). "Observations on the classification of the inflammatory myopathies". La Presse Médicale. 40 (4): e199–e208. doi:10.1016/j.lpm.2010.10.035. ISSN 0755-4982.
  12. Benveniste, Olivier; Léger, Jean-Marc (2011). "Inflammatory or necrotizing myopathies, myositides and other acquired myopathies, new insight in 2011". La Presse Médicale. 40 (4): e197–e198. doi:10.1016/j.lpm.2011.02.002. ISSN 0755-4982.
  13. Amato AA, Gronseth GS, Jackson CE, Wolfe GI, Katz JS, Bryan WW, Barohn RJ (October 1996). "Inclusion body myositis: clinical and pathological boundaries". Ann. Neurol. 40 (4): 581–6. doi:10.1002/ana.410400407. PMID 8871577.