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<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Reticulon-1''' also known as '''neuroendocrine-specific protein''' (NSP) is a [[protein]] that in humans is encoded by the ''RTN1'' [[gene]].<ref name="pmid8275708">{{cite journal | vauthors = Kools PF, Roebroek AJ, Van de Velde HJ, Marynen P, Bullerdiek J, Van de Ven WJ | title = Regional mapping of the human NSP gene to chromosome region 14q21→q22 by fluorescence in situ hybridization analysis | journal = Cytogenet Cell Genet | volume = 66 | issue = 1 | pages = 48–50 | date = February 1994 | pmid = 8275708 | pmc = | doi = 10.1159/000133662 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RTN1 reticulon 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6252| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
This gene belongs to the family of [[reticulon]]-encoding genes. Reticulons are associated with the [[endoplasmic reticulum]], and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. [[alternative splicing|Alternatively spliced]] transcript variants encoding different isoforms have been identified. Multiple promoters rather than alternative splicing of internal exons seem to be involved in this diversity.<ref name="entrez"/>
{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Reticulon 1
| HGNCid = 10467
| Symbol = RTN1
| AltSymbols =; MGC133250; NSP
| OMIM = 600865
| ECnumber = 
| Homologene = 49654
| MGIid = 1933947
| GeneAtlas_image1 = PBB_GE_RTN1_203485_at_tn.png
| GeneAtlas_image2 = PBB_GE_RTN1_210222_s_at_tn.png
| Function = {{GNF_GO|id=GO:0004871 |text = signal transducer activity}}
| Component = {{GNF_GO|id=GO:0005783 |text = endoplasmic reticulum}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}} {{GNF_GO|id=GO:0030176 |text = integral to endoplasmic reticulum membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0030182 |text = neuron differentiation}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 6252
    | Hs_Ensembl = ENSG00000139970
    | Hs_RefseqProtein = NP_066959
    | Hs_RefseqmRNA = NM_021136
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 14
    | Hs_GenLoc_start = 59132447
    | Hs_GenLoc_end = 59407310
    | Hs_Uniprot = Q16799
    | Mm_EntrezGene = 104001
    | Mm_Ensembl = ENSMUSG00000021087
    | Mm_RefseqmRNA = NM_001007596
    | Mm_RefseqProtein = NP_001007597
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 12
    | Mm_GenLoc_start = 73130586
    | Mm_GenLoc_end = 73327777
    | Mm_Uniprot = Q05CD8
  }}
}}
'''Reticulon 1''', also known as '''RTN1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: RTN1 reticulon 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6252| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Interactions ==
{{PBB_Summary
| section_title =  
| summary_text = This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. Alternatively spliced transcript variants encoding different isoforms have been identified. Multiple promoters rather than alternative splicing of internal exons seem to be involved in this diversity.<ref name="entrez">{{cite web | title = Entrez Gene: RTN1 reticulon 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6252| accessdate = }}</ref>
}}


==References==
RTN1 has been shown to [[Protein-protein interaction|interact]] with [[BCL2-like 1 (gene)|BCL2-like 1]]<ref name=pmid11126360>{{cite journal | vauthors = Tagami S, Eguchi Y, Kinoshita M, Takeda M, Tsujimoto Y | title = A novel protein, RTN-XS, interacts with both Bcl-XL and Bcl-2 on endoplasmic reticulum and reduces their anti-apoptotic activity | language =  | journal = Oncogene | volume = 19 | issue = 50 | pages = 5736–46 | date = November 2000 | pmid = 11126360 | doi = 10.1038/sj.onc.1203948 }}</ref> and [[UGCG]].<ref name=pmid12873973>{{cite journal | vauthors = Di Sano F, Fazi B, Citro G, Lovat PE, Cesareni G, Piacentini M | title = Glucosylceramide synthase and its functional interaction with RTN-1C regulate chemotherapeutic-induced apoptosis in neuroepithelioma cells | language =  | journal = Cancer Res. | volume = 63 | issue = 14 | pages = 3860–5 | date = July 2003 | pmid = 12873973 }}</ref>
{{reflist|2}}
 
==Further reading==
== References ==
{{reflist}}
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Senden NH, van de Velde HJ, Broers JL, Timmer ED, Roebroek AJ, van de Ven WJ, Ramaekers FC | title = Cluster-10 lung-cancer antibodies recognize NSPs, novel neuro-endocrine proteins associated with membranes of the endoplasmic reticulum | journal = Int. J. Cancer Suppl. | volume = 8 | issue =  | pages = 84–8 | year = 1994 | pmid = 7515034 | doi = 10.1002/ijc.2910570718 }}
| citations =
* {{cite journal | vauthors = Roebroek AJ, van de Velde HJ, Van Bokhoven A, Broers JL, Ramaekers FC, Van de Ven WJ | title = Cloning and expression of alternative transcripts of a novel neuroendocrine-specific gene and identification of its 135-kDa translational product | journal = J. Biol. Chem. | volume = 268 | issue = 18 | pages = 13439–47 | year = 1993 | pmid = 7685762 | doi =  }}
*{{cite journal | author=Senden NH, van de Velde HJ, Broers JL, ''et al.'' |title=Cluster-10 lung-cancer antibodies recognize NSPs, novel neuro-endocrine proteins associated with membranes of the endoplasmic reticulum. |journal=Int. J. Cancer Suppl. |volume=8 |issue=  |pages= 84-8 |year= 1994 |pmid= 7515034 |doi= }}
* {{cite journal | vauthors = van de Velde HJ, Roebroek AJ, Senden NH, Ramaekers FC, Van de Ven WJ | title = NSP-encoded reticulons, neuroendocrine proteins of a novel gene family associated with membranes of the endoplasmic reticulum | journal = J. Cell Sci. | volume = 107 | issue = 9 | pages = 2403–16 | year = 1995 | pmid = 7844160 | doi =  }}
*{{cite journal | author=Roebroek AJ, van de Velde HJ, Van Bokhoven A, ''et al.'' |title=Cloning and expression of alternative transcripts of a novel neuroendocrine-specific gene and identification of its 135-kDa translational product. |journal=J. Biol. Chem. |volume=268 |issue= 18 |pages= 13439-47 |year= 1993 |pmid= 7685762 |doi=  }}
* {{cite journal | vauthors = van de Velde HJ, Senden NH, Roskams TA, Broers JL, Ramaekers FC, Roebroek AJ, Van de Ven WJ | title = NSP-encoded reticulons are neuroendocrine markers of a novel category in human lung cancer diagnosis | journal = Cancer Res. | volume = 54 | issue = 17 | pages = 4769–76 | year = 1994 | pmid = 8062278 | doi =  }}
*{{cite journal | author=van de Velde HJ, Roebroek AJ, Senden NH, ''et al.'' |title=NSP-encoded reticulons, neuroendocrine proteins of a novel gene family associated with membranes of the endoplasmic reticulum. |journal=J. Cell. Sci. |volume=107 ( Pt 9) |issue= |pages= 2403-16 |year= 1995 |pmid= 7844160 |doi=  }}
* {{cite journal | vauthors = Roebroek AJ, Ayoubi TA, Van de Velde HJ, Schoenmakers EF, Pauli IG, Van de Ven WJ | title = Genomic organization of the human NSP gene, prototype of a novel gene family encoding reticulons | journal = Genomics | volume = 32 | issue = 2 | pages = 191–9 | year = 1997 | pmid = 8833145 | doi = 10.1006/geno.1996.0105 }}
*{{cite journal | author=van de Velde HJ, Senden NH, Roskams TA, ''et al.'' |title=NSP-encoded reticulons are neuroendocrine markers of a novel category in human lung cancer diagnosis. |journal=Cancer Res. |volume=54 |issue= 17 |pages= 4769-76 |year= 1994 |pmid= 8062278 |doi=  }}
* {{cite journal | vauthors = Bonaldo MF, Lennon G, Soares MB | title = Normalization and subtraction: two approaches to facilitate gene discovery | journal = Genome Res. | volume = 6 | issue = 9 | pages = 791–806 | year = 1997 | pmid = 8889548 | doi = 10.1101/gr.6.9.791 }}
*{{cite journal | author=Kools PF, Roebroek AJ, Van de Velde HJ, ''et al.'' |title=Regional mapping of the human NSP gene to chromosome region 14q21-->q22 by fluorescence in situ hybridization analysis. |journal=Cytogenet. Cell Genet. |volume=66 |issue= 1 |pages= 48-50 |year= 1994 |pmid= 8275708 |doi= }}
* {{cite journal | vauthors = Senden NH, Timmer ED, Boers JE, van de Velde HJ, Roebroek AJ, Van de Ven WJ, Broers JL, Ramaekers FC | title = Neuroendocrine-specific protein C (NSP-C): subcellular localization and differential expression in relation to NSP-A | journal = Eur. J. Cell Biol. | volume = 69 | issue = 3 | pages = 197–213 | year = 1996 | pmid = 8900485 | doi =  }}
*{{cite journal | author=Roebroek AJ, Ayoubi TA, Van de Velde HJ, ''et al.'' |title=Genomic organization of the human NSP gene, prototype of a novel gene family encoding reticulons. |journal=Genomics |volume=32 |issue= 2 |pages= 191-9 |year= 1997 |pmid= 8833145 |doi= 10.1006/geno.1996.0105 }}
* {{cite journal | vauthors = Hens J, Nuydens R, Geerts H, Senden NH, Van de Ven WJ, Roebroek AJ, van de Velde HJ, Ramaekers FC, Broers JL | title = Neuronal differentiation is accompanied by NSP-C expression | journal = Cell Tissue Res. | volume = 292 | issue = 2 | pages = 229–37 | year = 1998 | pmid = 9560466 | doi = 10.1007/s004410051054 }}
*{{cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791-806 |year= 1997 |pmid= 8889548 |doi=  }}
* {{cite journal | vauthors = Tagami S, Eguchi Y, Kinoshita M, Takeda M, Tsujimoto Y | title = A novel protein, RTN-XS, interacts with both Bcl-XL and Bcl-2 on endoplasmic reticulum and reduces their anti-apoptotic activity | journal = Oncogene | volume = 19 | issue = 50 | pages = 5736–46 | year = 2001 | pmid = 11126360 | doi = 10.1038/sj.onc.1203948 }}
*{{cite journal | author=Senden NH, Timmer ED, Boers JE, ''et al.'' |title=Neuroendocrine-specific protein C (NSP-C): subcellular localization and differential expression in relation to NSP-A. |journal=Eur. J. Cell Biol. |volume=69 |issue= 3 |pages= 197-213 |year= 1996 |pmid= 8900485 |doi= }}
* {{cite journal | vauthors = Oertle T, Klinger M, Stuermer CA, Schwab ME | title = A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family | journal = FASEB J. | volume = 17 | issue = 10 | pages = 1238–47 | year = 2003 | pmid = 12832288 | doi = 10.1096/fj.02-1166hyp }}
*{{cite journal | author=Hens J, Nuydens R, Geerts H, ''et al.'' |title=Neuronal differentiation is accompanied by NSP-C expression. |journal=Cell Tissue Res. |volume=292 |issue= 2 |pages= 229-37 |year= 1998 |pmid= 9560466 |doi= }}
* {{cite journal | vauthors = Di Sano F, Fazi B, Citro G, Lovat PE, Cesareni G, Piacentini M | title = Glucosylceramide synthase and its functional interaction with RTN-1C regulate chemotherapeutic-induced apoptosis in neuroepithelioma cells | journal = Cancer Res. | volume = 63 | issue = 14 | pages = 3860–5 | year = 2003 | pmid = 12873973 | doi = }}
*{{cite journal | author=Tagami S, Eguchi Y, Kinoshita M, ''et al.'' |title=A novel protein, RTN-XS, interacts with both Bcl-XL and Bcl-2 on endoplasmic reticulum and reduces their anti-apoptotic activity. |journal=Oncogene |volume=19 |issue= 50 |pages= 5736-46 |year= 2001 |pmid= 11126360 |doi= 10.1038/sj.onc.1203948 }}
* {{cite journal | vauthors = Iwahashi J, Hamada N | title = Human reticulon 1-A and 1-B interact with a medium chain of the AP-2 adaptor complex | journal = Cell. Mol. Biol. (Noisy-le-grand) | volume = 49 Online Pub | issue = | pages = OL467–71 | year = 2004 | pmid = 14995077 | doi = }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
* {{cite journal | vauthors = Hu Y, Fang X, Dunham SM, Prada C, Stachowiak EK, Stachowiak MK | title = 90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling | journal = J. Biol. Chem. | volume = 279 | issue = 28 | pages = 29325–35 | year = 2004 | pmid = 15117958 | doi = 10.1074/jbc.M311144200 }}
*{{cite journal | author=Oertle T, Klinger M, Stuermer CA, Schwab ME |title=A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family. |journal=FASEB J. |volume=17 |issue= 10 |pages= 1238-47 |year= 2003 |pmid= 12832288 |doi= 10.1096/fj.02-1166hyp }}
* {{cite journal | vauthors = He W, Lu Y, Qahwash I, Hu XY, Chang A, Yan R | title = Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation | journal = Nat. Med. | volume = 10 | issue = 9 | pages = 959–65 | year = 2004 | pmid = 15286784 | doi = 10.1038/nm1088 }}
*{{cite journal | author=Di Sano F, Fazi B, Citro G, ''et al.'' |title=Glucosylceramide synthase and its functional interaction with RTN-1C regulate chemotherapeutic-induced apoptosis in neuroepithelioma cells. |journal=Cancer Res. |volume=63 |issue= 14 |pages= 3860-5 |year= 2003 |pmid= 12873973 |doi= }}
* {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | year = 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
* {{cite journal | vauthors = Mannan AU, Boehm J, Sauter SM, Rauber A, Byrne PC, Neesen J, Engel W | title = Spastin, the most commonly mutated protein in hereditary spastic paraplegia interacts with Reticulon 1 an endoplasmic reticulum protein | journal = Neurogenetics | volume = 7 | issue = 2 | pages = 93–103 | year = 2007 | pmid = 16602018 | doi = 10.1007/s10048-006-0034-4 }}
*{{cite journal | author=Iwahashi J, Hamada N |title=Human reticulon 1-A and 1-B interact with a medium chain of the AP-2 adaptor complex. |journal=Cell. Mol. Biol. (Noisy-le-grand) |volume=49 Online Pub |issue= |pages= OL467-71 |year= 2004 |pmid= 14995077 |doi= }}
*{{cite journal | author=Hu Y, Fang X, Dunham SM, ''et al.'' |title=90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling. |journal=J. Biol. Chem. |volume=279 |issue= 28 |pages= 29325-35 |year= 2004 |pmid= 15117958 |doi= 10.1074/jbc.M311144200 }}
*{{cite journal  | author=He W, Lu Y, Qahwash I, ''et al.'' |title=Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation. |journal=Nat. Med. |volume=10 |issue= 9 |pages= 959-65 |year= 2004 |pmid= 15286784 |doi= 10.1038/nm1088 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal  | author=Mannan AU, Boehm J, Sauter SM, ''et al.'' |title=Spastin, the most commonly mutated protein in hereditary spastic paraplegia interacts with Reticulon 1 an endoplasmic reticulum protein. |journal=Neurogenetics |volume=7 |issue= 2 |pages= 93-103 |year= 2007 |pmid= 16602018 |doi= 10.1007/s10048-006-0034-4 }}
}}
{{refend}}
{{refend}}


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Latest revision as of 20:45, 8 November 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Reticulon-1 also known as neuroendocrine-specific protein (NSP) is a protein that in humans is encoded by the RTN1 gene.[1][2]

This gene belongs to the family of reticulon-encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. Alternatively spliced transcript variants encoding different isoforms have been identified. Multiple promoters rather than alternative splicing of internal exons seem to be involved in this diversity.[2]

Interactions

RTN1 has been shown to interact with BCL2-like 1[3] and UGCG.[4]

References

  1. ↑ Kools PF, Roebroek AJ, Van de Velde HJ, Marynen P, Bullerdiek J, Van de Ven WJ (February 1994). "Regional mapping of the human NSP gene to chromosome region 14q21→q22 by fluorescence in situ hybridization analysis". Cytogenet Cell Genet. 66 (1): 48–50. doi:10.1159/000133662. PMID 8275708.
  2. ↑ 2.0 2.1 "Entrez Gene: RTN1 reticulon 1".
  3. ↑ Tagami S, Eguchi Y, Kinoshita M, Takeda M, Tsujimoto Y (November 2000). "A novel protein, RTN-XS, interacts with both Bcl-XL and Bcl-2 on endoplasmic reticulum and reduces their anti-apoptotic activity". Oncogene. 19 (50): 5736–46. doi:10.1038/sj.onc.1203948. PMID 11126360.
  4. ↑ Di Sano F, Fazi B, Citro G, Lovat PE, Cesareni G, Piacentini M (July 2003). "Glucosylceramide synthase and its functional interaction with RTN-1C regulate chemotherapeutic-induced apoptosis in neuroepithelioma cells". Cancer Res. 63 (14): 3860–5. PMID 12873973.

Further reading

  • Senden NH, van de Velde HJ, Broers JL, Timmer ED, Roebroek AJ, van de Ven WJ, Ramaekers FC (1994). "Cluster-10 lung-cancer antibodies recognize NSPs, novel neuro-endocrine proteins associated with membranes of the endoplasmic reticulum". Int. J. Cancer Suppl. 8: 84–8. doi:10.1002/ijc.2910570718. PMID 7515034.
  • Roebroek AJ, van de Velde HJ, Van Bokhoven A, Broers JL, Ramaekers FC, Van de Ven WJ (1993). "Cloning and expression of alternative transcripts of a novel neuroendocrine-specific gene and identification of its 135-kDa translational product". J. Biol. Chem. 268 (18): 13439–47. PMID 7685762.
  • van de Velde HJ, Roebroek AJ, Senden NH, Ramaekers FC, Van de Ven WJ (1995). "NSP-encoded reticulons, neuroendocrine proteins of a novel gene family associated with membranes of the endoplasmic reticulum". J. Cell Sci. 107 (9): 2403–16. PMID 7844160.
  • van de Velde HJ, Senden NH, Roskams TA, Broers JL, Ramaekers FC, Roebroek AJ, Van de Ven WJ (1994). "NSP-encoded reticulons are neuroendocrine markers of a novel category in human lung cancer diagnosis". Cancer Res. 54 (17): 4769–76. PMID 8062278.
  • Roebroek AJ, Ayoubi TA, Van de Velde HJ, Schoenmakers EF, Pauli IG, Van de Ven WJ (1997). "Genomic organization of the human NSP gene, prototype of a novel gene family encoding reticulons". Genomics. 32 (2): 191–9. doi:10.1006/geno.1996.0105. PMID 8833145.
  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
  • Senden NH, Timmer ED, Boers JE, van de Velde HJ, Roebroek AJ, Van de Ven WJ, Broers JL, Ramaekers FC (1996). "Neuroendocrine-specific protein C (NSP-C): subcellular localization and differential expression in relation to NSP-A". Eur. J. Cell Biol. 69 (3): 197–213. PMID 8900485.
  • Hens J, Nuydens R, Geerts H, Senden NH, Van de Ven WJ, Roebroek AJ, van de Velde HJ, Ramaekers FC, Broers JL (1998). "Neuronal differentiation is accompanied by NSP-C expression". Cell Tissue Res. 292 (2): 229–37. doi:10.1007/s004410051054. PMID 9560466.
  • Tagami S, Eguchi Y, Kinoshita M, Takeda M, Tsujimoto Y (2001). "A novel protein, RTN-XS, interacts with both Bcl-XL and Bcl-2 on endoplasmic reticulum and reduces their anti-apoptotic activity". Oncogene. 19 (50): 5736–46. doi:10.1038/sj.onc.1203948. PMID 11126360.
  • Oertle T, Klinger M, Stuermer CA, Schwab ME (2003). "A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family". FASEB J. 17 (10): 1238–47. doi:10.1096/fj.02-1166hyp. PMID 12832288.
  • Di Sano F, Fazi B, Citro G, Lovat PE, Cesareni G, Piacentini M (2003). "Glucosylceramide synthase and its functional interaction with RTN-1C regulate chemotherapeutic-induced apoptosis in neuroepithelioma cells". Cancer Res. 63 (14): 3860–5. PMID 12873973.
  • Iwahashi J, Hamada N (2004). "Human reticulon 1-A and 1-B interact with a medium chain of the AP-2 adaptor complex". Cell. Mol. Biol. (Noisy-le-grand). 49 Online Pub: OL467–71. PMID 14995077.
  • Hu Y, Fang X, Dunham SM, Prada C, Stachowiak EK, Stachowiak MK (2004). "90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling". J. Biol. Chem. 279 (28): 29325–35. doi:10.1074/jbc.M311144200. PMID 15117958.
  • He W, Lu Y, Qahwash I, Hu XY, Chang A, Yan R (2004). "Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation". Nat. Med. 10 (9): 959–65. doi:10.1038/nm1088. PMID 15286784.
  • Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
  • Mannan AU, Boehm J, Sauter SM, Rauber A, Byrne PC, Neesen J, Engel W (2007). "Spastin, the most commonly mutated protein in hereditary spastic paraplegia interacts with Reticulon 1 an endoplasmic reticulum protein". Neurogenetics. 7 (2): 93–103. doi:10.1007/s10048-006-0034-4. PMID 16602018.


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