UBE1L2: Difference between revisions

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{{Infobox_gene}}
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'''Ubiquitin-like modifier-activating enzyme 6''' is a [[protein]] that in humans is encoded by the ''UBA6'' [[gene]].<ref name="pmid17580310">{{cite journal |vauthors=Pelzer C, Kassner I, Matentzoglu K, Singh RK, Wollscheid HP, Scheffner M, Schmidtke G, Groettrup M | title = UBE1L2, a novel E1 enzyme specific for ubiquitin | journal = J Biol Chem | volume = 282 | issue = 32 | pages = 23010–4 |date=Aug 2007 | pmid = 17580310 | pmc =  | doi = 10.1074/jbc.C700111200 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: UBE1L2 ubiquitin-activating enzyme E1-like 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55236| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Ubiquitin-activating enzyme E1-like 2
| HGNCid = 25581
| Symbol = UBE1L2
| AltSymbols =; FLJ10808; FLJ23367
| OMIM =
| ECnumber =
| Homologene = 10080
| MGIid = 1913894
  | GeneAtlas_image1 = PBB_GE_UBE1L2_218340_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_UBE1L2_gnf1h04252_at_tn.png
| GeneAtlas_image3 = PBB_GE_UBE1L2_gnf1h09316_s_at_tn.png
| Function =
| Component =
| Process =
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 55236
    | Hs_Ensembl = ENSG00000033178
    | Hs_RefseqProtein = NP_060697
    | Hs_RefseqmRNA = NM_018227
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 4
    | Hs_GenLoc_start = 68165123
    | Hs_GenLoc_end = 68249453
    | Hs_Uniprot = 
    | Mm_EntrezGene = 231380
    | Mm_Ensembl = ENSMUSG00000035898
    | Mm_RefseqmRNA = NM_172712
    | Mm_RefseqProtein = NP_766300
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 5
    | Mm_GenLoc_start = 87185278
    | Mm_GenLoc_end = 87247304
    | Mm_Uniprot = 
  }}
}}
'''Ubiquitin-activating enzyme E1-like 2''', also known as '''UBE1L2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: UBE1L2 ubiquitin-activating enzyme E1-like 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55236| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788-95 |year= 2001 |pmid= 11076863 |doi=  }}
*{{cite journal  |vauthors=Hartley JL, Temple GF, Brasch MA |title=DNA Cloning Using In Vitro Site-Specific Recombination |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=10.1101/gr.143000  | pmc=310948 }}
*{{cite journal  | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422-35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701 }}
*{{cite journal  | author=Wiemann S |title=Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.GR1547R  | pmc=311072  |name-list-format=vanc| author2=Weil B  | author3=Wellenreuther R  | display-authors=3  | last4=Gassenhuber  | first4=J  | last5=Glassl  | first5=S  | last6=Ansorge  | first6=W  | last7=Böcher  | first7=M  | last8=Blöcker  | first8=H  | last9=Bauersachs  | first9=S }}
*{{cite journal  | author=Simpson JC, Wellenreuther R, Poustka A, ''et al.'' |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287-92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058 }}
*{{cite journal  | author=Simpson JC |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287–92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058 | pmc=1083732  |name-list-format=vanc| author2=Wellenreuther R  | author3=Poustka A  | display-authors=3  | last4=Pepperkok  | first4=R  | last5=Wiemann  | first5=S }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |name-list-format=vanc| author2=Suzuki Y  | author3=Nishikawa T  | display-authors=3  | last4=Otsuki  | first4=Tetsuji  | last5=Sugiyama  | first5=Tomoyasu  | last6=Irie  | first6=Ryotaro  | last7=Wakamatsu  | first7=Ai  | last8=Hayashi  | first8=Koji  | last9=Sato  | first9=Hiroyuki }}
*{{cite journal  | author=Zhu H, Zhou ZM, Huo R, ''et al.'' |title=Identification and characteristics of a novel E1 like gene nUBE1L in human testis. |journal=Acta Biochim. Biophys. Sin. (Shanghai) |volume=36 |issue= 3 |pages= 227-34 |year= 2004 |pmid= 15202508 |doi=  }}
*{{cite journal  | author=Zhu H |title=Identification and characteristics of a novel E1 like gene nUBE1L in human testis |journal=Acta Biochim. Biophys. Sin. (Shanghai) |volume=36 |issue= 3 |pages= 227–34 |year= 2004 |pmid= 15202508 |doi=10.1093/abbs/36.3.227  |name-list-format=vanc| author2=Zhou ZM  | author3=Huo R  | display-authors=3  | last4=Huang  | first4=X.-Y.  | last5=Lu  | first5=L.  | last6=Lin  | first6=M.  | last7=Wang  | first7=L.-R.  | last8=Zhou  | first8=Y.-D.  | last9=Li  | first9=J.-M. }}
*{{cite journal  | author=Colland F, Jacq X, Trouplin V, ''et al.'' |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324-32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 }}
*{{cite journal  | author=Colland F |title=Functional Proteomics Mapping of a Human Signaling Pathway |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 | pmc=442148  |name-list-format=vanc| author2=Jacq X  | author3=Trouplin V  | display-authors=3  | last4=Mougin  | first4=C  | last5=Groizeleau  | first5=C  | last6=Hamburger  | first6=A  | last7=Meil  | first7=A  | last8=Wojcik  | first8=J  | last9=Legrain  | first9=P }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928  |name-list-format=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
*{{cite journal  | author=Wiemann S, Arlt D, Huber W, ''et al.'' |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136-44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 }}
*{{cite journal  | author=Wiemann S |title=From ORFeome to Biology: A Functional Genomics Pipeline |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 | pmc=528930  |name-list-format=vanc| author2=Arlt D  | author3=Huber W  | display-authors=3  | last4=Wellenreuther  | first4=R  | last5=Schleeger  | first5=S  | last6=Mehrle  | first6=A  | last7=Bechtel  | first7=S  | last8=Sauermann  | first8=M  | last9=Korf  | first9=U }}
*{{cite journal  | author=Hillier LW, Graves TA, Fulton RS, ''et al.'' |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |journal=Nature |volume=434 |issue= 7034 |pages= 724-31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466 }}
*{{cite journal  | author=Hillier LW |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4 |journal=Nature |volume=434 |issue= 7034 |pages= 724–31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466 |name-list-format=vanc| author2=Graves TA  | author3=Fulton RS  | display-authors=3  | last4=Fulton  | first4=Lucinda A.  | last5=Pepin  | first5=Kymberlie H.  | last6=Minx  | first6=Patrick  | last7=Wagner-Mcpherson  | first7=Caryn  | last8=Layman  | first8=Dan  | last9=Wylie  | first9=Kristine }}
*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal  | author=Rual JF |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |name-list-format=vanc| author2=Venkatesan K  | author3=Hao T  | display-authors=3  | last4=Hirozane-Kishikawa  | first4=Tomoko  | last5=Dricot  | first5=Amélie  | last6=Li  | first6=Ning  | last7=Berriz  | first7=Gabriel F.  | last8=Gibbons  | first8=Francis D.  | last9=Dreze  | first9=Matija }}
*{{cite journal  | author=Mehrle A, Rosenfelder H, Schupp I, ''et al.'' |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415-8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139 }}
*{{cite journal  | author=Mehrle A |title=The LIFEdb database in 2006 |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139  | pmc=1347501  |name-list-format=vanc| author2=Rosenfelder H  | author3=Schupp I  | display-authors=3  | last4=Del Val  | first4=C | last5=Arlt  | first5=D  | last6=Hahne  | first6=F  | last7=Bechtel  | first7=S  | last8=Simpson  | first8=J  | last9=Hofmann  | first9=O }}
*{{cite journal | author=Pelzer C, Kassner I, Matentzoglu K, ''et al.'' |title=UBE1L2, a novel E1 enzyme specific for ubiquitin. |journal=J. Biol. Chem. |volume=282 |issue= 32 |pages= 23010-4 |year= 2007 |pmid= 17580310 |doi= 10.1074/jbc.C700111200 }}
*{{cite journal  |vauthors=Jin J, Li X, Gygi SP, Harper JW |title=Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging |journal=Nature |volume=447 |issue= 7148 |pages= 1135–8 |year= 2007 |pmid= 17597759 |doi= 10.1038/nature05902 }}
*{{cite journal  | author=Jin J, Li X, Gygi SP, Harper JW |title=Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging. |journal=Nature |volume=447 |issue= 7148 |pages= 1135-8 |year= 2007 |pmid= 17597759 |doi= 10.1038/nature05902 }}
*{{cite journal  |vauthors=Chiu YH, Sun Q, Chen ZJ |title=E1-L2 activates both ubiquitin and FAT10 |journal=Mol. Cell |volume=27 |issue= 6 |pages= 1014–23 |year= 2007 |pmid= 17889673 |doi= 10.1016/j.molcel.2007.08.020 }}
*{{cite journal  | author=Chiu YH, Sun Q, Chen ZJ |title=E1-L2 activates both ubiquitin and FAT10. |journal=Mol. Cell |volume=27 |issue= 6 |pages= 1014-23 |year= 2007 |pmid= 17889673 |doi= 10.1016/j.molcel.2007.08.020 }}
}}
}}
{{refend}}
{{refend}}


{{protein-stub}}
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{{gene-4-stub}}

Latest revision as of 09:30, 17 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Ubiquitin-like modifier-activating enzyme 6 is a protein that in humans is encoded by the UBA6 gene.[1][2]


References

  1. ↑ Pelzer C, Kassner I, Matentzoglu K, Singh RK, Wollscheid HP, Scheffner M, Schmidtke G, Groettrup M (Aug 2007). "UBE1L2, a novel E1 enzyme specific for ubiquitin". J Biol Chem. 282 (32): 23010–4. doi:10.1074/jbc.C700111200. PMID 17580310.
  2. ↑ "Entrez Gene: UBE1L2 ubiquitin-activating enzyme E1-like 2".

Further reading



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