Myxedema coma natural history, complications, and prognosis: Difference between revisions
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==Overview== | ==Overview== | ||
==Natural History== | ==Natural History== | ||
==Complications== | ==Complications== | ||
Common complications of myxedema coma include: | Common complications of myxedema coma include: |
Revision as of 01:02, 10 October 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
Natural History
Complications
Common complications of myxedema coma include:
- Treatment-induced congestive heart failure in patients with coronary artery disease
- Increased susceptibility to infection
- Organic psychosis with paranoia
- Adrenal crisis with vigorous treatment of hypothyroidism
- Hypersensitivity to opiates
- Pericardial effusion
- Cardiac tamponade
Prognosis
- The mortality rate in myxedema coma is 20% to 25% despite aggressive therapy.[1][2]
- The most common causes of death are respiratory failure, sepsis, and gastrointestinal bleeding.
Factors suggesting a poor prognosis
- Older age
- Persistent hypothermia
- Bradycardia
- Lower degree of consciousness by Glasgow Coma Scale
- Multiorgan impairment indicated by high APACHE (Acute Physiology and Chronic Health Evaluation) II score.