Myxedema coma natural history, complications, and prognosis: Difference between revisions
Aditya Ganti (talk | contribs) |
Aditya Ganti (talk | contribs) |
||
Line 15: | Line 15: | ||
==Prognosis== | ==Prognosis== | ||
*The mortality rate in myxedema coma is 20% to 25% despite aggressive therapy. | *The mortality rate in myxedema coma is 20% to 25% despite aggressive therapy.<ref name="pmid11130234">{{cite journal |vauthors=Wall CR |title=Myxedema coma: diagnosis and treatment |journal=Am Fam Physician |volume=62 |issue=11 |pages=2485–90 |year=2000 |pmid=11130234 |doi= |url=}}</ref> | ||
*The most common causes of death are respiratory failure, sepsis, and gastrointestinal bleeding. | *The most common causes of death are respiratory failure, sepsis, and gastrointestinal bleeding. | ||
===Factors suggesting a poor prognosis === | ===Factors suggesting a poor prognosis === |
Revision as of 01:00, 10 October 2017
Myxedema coma Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Myxedema coma natural history, complications, and prognosis On the Web |
American Roentgen Ray Society Images of Myxedema coma natural history, complications, and prognosis |
FDA on Myxedema coma natural history, complications, and prognosis |
CDC on Myxedema coma natural history, complications, and prognosis |
Myxedema coma natural history, complications, and prognosis in the news |
Blogs on Myxedema coma natural history, complications, and prognosis |
Risk calculators and risk factors for Myxedema coma natural history, complications, and prognosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
Natural History
Complications
Common complications of myxedema coma include:
- Treatment-induced congestive heart failure in patients with coronary artery disease
- Increased susceptibility to infection
- Organic psychosis with paranoia
- Adrenal crisis with vigorous treatment of hypothyroidism
- Hypersensitivity to opiates
- Pericardial effusion
- Cardiac tamponade
Prognosis
- The mortality rate in myxedema coma is 20% to 25% despite aggressive therapy.[1]
- The most common causes of death are respiratory failure, sepsis, and gastrointestinal bleeding.
Factors suggesting a poor prognosis
- Older age
- Persistent hypothermia
- Bradycardia
- Lower degree of consciousness by Glasgow Coma Scale
- Multiorgan impairment indicated by high APACHE (Acute Physiology and Chronic Health Evaluation) II score.