Sheehan's syndrome laboratory findings: Difference between revisions

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==Laboratory Findings==
==Laboratory Findings==
*Laboratory findings consistent with the diagnosis of Sheehan syndrome include:  
*Laboratory findings consistent with the diagnosis of Sheehan syndrome include:  
**Hyponatremia
**Hyponatremia<ref name="pmid8797063">{{cite journal |vauthors=Shoji M, Kimura T, Ota K, Ohta M, Sato K, Yamamoto T, Funyu T, Mori T, Tateyama M, Abe K |title=Cortical laminar necrosis and central pontine myelinolysis in a patient with Sheehan syndrome and severe hyponatremia |journal=Intern. Med. |volume=35 |issue=5 |pages=427–31 |year=1996 |pmid=8797063 |doi= |url=}}</ref><ref name="pmid1957856">{{cite journal |vauthors=Putterman C, Almog Y, Caraco Y, Gross DJ, Ben-Chetrit E |title=Inappropriate secretion of antidiuretic hormone in Sheehan's syndrome: a rare cause of postpartum hyponatremia |journal=Am. J. Obstet. Gynecol. |volume=165 |issue=5 Pt 1 |pages=1330–3 |year=1991 |pmid=1957856 |doi= |url=}}</ref><ref name="pmid19705625">{{cite journal |vauthors=Anfuso S, Patrelli TS, Soncini E, Chiodera P, Fadda GM, Nardelli GB |title=A case report of Sheehan's syndrome with acute onset, hyponatremia and severe anemia |journal=Acta Biomed |volume=80 |issue=1 |pages=73–6 |year=2009 |pmid=19705625 |doi= |url=}}</ref>
**Hypokalemia
**Hypokalemia
**Hypocalcemia
**Hypocalcemia
**Hypomagnesemia
**Hypomagnesemia
**Hypophosphatemia
**Hypophosphatemia
**Anemia<ref name="pmid19705625">{{cite journal |vauthors=Anfuso S, Patrelli TS, Soncini E, Chiodera P, Fadda GM, Nardelli GB |title=A case report of Sheehan's syndrome with acute onset, hyponatremia and severe anemia |journal=Acta Biomed |volume=80 |issue=1 |pages=73–6 |year=2009 |pmid=19705625 |doi= |url=}}</ref>
**Thrombocytopenia
**Decreased levels of anterior pituitary hormones in blood.
**Decreased levels of anterior pituitary hormones in blood.
*Most sensitive test is inadequate prolactin and gonadotropin responses to stimulation.
*Most sensitive test is inadequate prolactin and gonadotropin responses to stimulation.

Revision as of 21:57, 16 August 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

  • An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
  • Laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].
  • [Test] is usually normal among patients with [disease name].
  • Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].

OR

  • There are no diagnostic laboratory findings associated with [disease name].

Laboratory Findings

  • Laboratory findings consistent with the diagnosis of Sheehan syndrome include:
    • Hyponatremia[1][2][3]
    • Hypokalemia
    • Hypocalcemia
    • Hypomagnesemia
    • Hypophosphatemia
    • Anemia[3]
    • Thrombocytopenia
    • Decreased levels of anterior pituitary hormones in blood.
  • Most sensitive test is inadequate prolactin and gonadotropin responses to stimulation.
  • Baseline and stimulated anterior pituitary hormone level measurements.

References

  1. Shoji M, Kimura T, Ota K, Ohta M, Sato K, Yamamoto T, Funyu T, Mori T, Tateyama M, Abe K (1996). "Cortical laminar necrosis and central pontine myelinolysis in a patient with Sheehan syndrome and severe hyponatremia". Intern. Med. 35 (5): 427–31. PMID 8797063.
  2. Putterman C, Almog Y, Caraco Y, Gross DJ, Ben-Chetrit E (1991). "Inappropriate secretion of antidiuretic hormone in Sheehan's syndrome: a rare cause of postpartum hyponatremia". Am. J. Obstet. Gynecol. 165 (5 Pt 1): 1330–3. PMID 1957856.
  3. 3.0 3.1 Anfuso S, Patrelli TS, Soncini E, Chiodera P, Fadda GM, Nardelli GB (2009). "A case report of Sheehan's syndrome with acute onset, hyponatremia and severe anemia". Acta Biomed. 80 (1): 73–6. PMID 19705625.

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