Hirschsprung's disease other diagnostic studies: Difference between revisions
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==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
A rectal [[biopsy]] showing a lack of ganglionic cells is the gold standard confirmatory test for Hirschsprung's disease. | A rectal [[biopsy]] showing a lack of ganglionic cells is the gold standard confirmatory test for Hirschsprung's disease. | ||
{| class="wikitable" | |||
!Diagnostic Test | |||
!FIndings | |||
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|Rectal biopsy | |||
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* Absence of ganglion cells | |||
* Presence of thickened, nonmyelinated nerves | |||
* Increased activity of acetylcholinesterase; absence of nicotinamide adenine dinucleotide phosphate diaphorase-containing neurons | |||
* Increase in the amount of acetylcholinesterase-containing nerve bundles | |||
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|Enema | |||
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* Contracted distal bowel and dilated proximal bowel, with demonstration of the location of the transition zone in between | |||
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|Anorectal manometry | |||
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* Absent anal reflex and increased pressure | |||
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==References== | ==References== | ||
Revision as of 12:54, 16 June 2017
Hirschsprung's disease Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Other diagnostic studies include rectal biopsy, barium enema and anorectal manometry. A rectal biopsy showing a lack of ganglionic cells is the gold standard confirmatory test for Hirschsprung's disease.
Other Diagnostic Studies
A rectal biopsy showing a lack of ganglionic cells is the gold standard confirmatory test for Hirschsprung's disease.
Diagnostic Test | FIndings | ||
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Rectal biopsy |
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Enema |
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Anorectal manometry |
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