Epithelioid sarcoma other diagnostic studies: Difference between revisions

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__NOTOC__
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{{Epithelioid sarcome}}
{{Epithelioid sarcoma}}
{{CMG}}; {{AE}} {{Ammu}}
{{CMG}}; {{AE}} {{Ammu}}
==Overview==
==Overview==
==Genetic Testing==
==Genetic Testing==
*Loss of  INI1 (also known as hSNF5 and SMARCB1) which is a member of SWI/SNF multi subunit chromatin remodeling complex located on the long arm of chromosome 22 (22q11.2) has been a diagnostic modalty of epithelioid sarcome.
*Loss of  INI1 (also known as hSNF5 and SMARCB1) which is a member of SWI/SNF multi subunit chromatin remodeling complex located on the long arm of chromosome 22 (22q11.2) has been a diagnostic modalty of epithelioid sarcoma.
==Immunohistochemistry==
* Vimentin reactivity
* Pankeratin AE1/AE3 and epithelial membrane antigen
* Negative  S100
==Reference==
==Reference==
{{Reflist|2}}
{{Reflist|2}}

Revision as of 20:15, 9 February 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

Genetic Testing

  • Loss of INI1 (also known as hSNF5 and SMARCB1) which is a member of SWI/SNF multi subunit chromatin remodeling complex located on the long arm of chromosome 22 (22q11.2) has been a diagnostic modalty of epithelioid sarcoma.

Immunohistochemistry

  • Vimentin reactivity
  • Pankeratin AE1/AE3 and epithelial membrane antigen
  • Negative S100

Reference