Hepatocellular adenoma natural history: Difference between revisions

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==Overview==
==Overview==
If left untreated, 30% of patients with hepatocellular adenoma may progress to develop risk of bleeding.<ref>Hepatocellular adenoma.Wikipedia 2015. https://en.wikipedia.org/wiki/Hepatocellular_adenoma Accessed on October 16, 2015 </ref>Common complication of Hepatocellular adenoma includes spontaneous rupture, haemorrhage<ref name=a>{{cite web | title = Radiopedia 2015 Hepatic adenoma [Dr Matt A. Morgan and Dr Koshy Jacob]| url = http://radiopaedia.org/articles/hepatic-adenoma }}</ref><ref name="pmid25786843">{{cite journal| author=Aamann L, Schultz N, Fallentin E, Hamilton-Dutoit S, Vogel I, Grønbæk H| title=[Hepatocellular adenoma - new classification and recommendations]. | journal=Ugeskr Laeger | year= 2015 | volume= 177 | issue= 12 | pages=  | pmid=25786843 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25786843  }} </ref>and malignant transformation to Hepatocellular carcinoma.<ref name="pmid25786843">{{cite journal| author=Aamann L, Schultz N, Fallentin E, Hamilton-Dutoit S, Vogel I, Grønbæk H| title=[Hepatocellular adenoma - new classification and recommendations]. | journal=Ugeskr Laeger | year= 2015 | volume= 177 | issue= 12 | pages=  | pmid=25786843 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25786843  }} </ref>
==Hepatocellular adenoma natural history==
==Hepatocellular adenoma natural history==
If left untreated, 30% of patients with hepatocellular adenoma may progress to develop risk of bleeding.<ref>Hepatocellular adenoma.Wikipedia 2015. https://en.wikipedia.org/wiki/Hepatocellular_adenoma Accessed on October 16, 2015 </ref>
==Complications==
==Complications==
Common complication of hepatocellular adenoma include:
Common complication of hepatocellular adenoma include:
* Spontaneous rupture and subsequently haemorrhage<ref name=a>{{cite web | title = Radiopedia 2015 Hepatic adenoma [Dr Matt A. Morgan and Dr Koshy Jacob]| url = http://radiopaedia.org/articles/hepatic-adenoma }}</ref><ref name="pmid25786843">{{cite journal| author=Aamann L, Schultz N, Fallentin E, Hamilton-Dutoit S, Vogel I, Grønbæk H| title=[Hepatocellular adenoma - new classification and recommendations]. | journal=Ugeskr Laeger | year= 2015 | volume= 177 | issue= 12 | pages=  | pmid=25786843 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25786843  }} </ref>
* Spontaneous rupture and subsequently haemorrhage<ref name=a>{{cite web | title = Radiopedia 2015 Hepatic adenoma [Dr Matt A. Morgan and Dr Koshy Jacob]| url = http://radiopaedia.org/articles/hepatic-adenoma }}</ref><ref name="pmid25786843">{{cite journal| author=Aamann L, Schultz N, Fallentin E, Hamilton-Dutoit S, Vogel I, Grønbæk H| title=[Hepatocellular adenoma - new classification and recommendations]. | journal=Ugeskr Laeger | year= 2015 | volume= 177 | issue= 12 | pages=  | pmid=25786843 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25786843  }} </ref>
* Although uncommon, hepatic adenomas do rarely degenerate into hepatocellular carcinomas (HCC).<ref name=a>{{cite web | title = Radiopedia 2015 Hepatic adenoma [Dr Matt A. Morgan and Dr Koshy Jacob]| url = http://radiopaedia.org/articles/hepatic-adenoma }}</ref> The risk factor for malignant transformation of hepatic adenoma to hepatocellular carcinoma is:<ref name="pmid25786843">{{cite journal| author=Aamann L, Schultz N, Fallentin E, Hamilton-Dutoit S, Vogel I, Grønbæk H| title=[Hepatocellular adenoma - new classification and recommendations]. | journal=Ugeskr Laeger | year= 2015 | volume= 177 | issue= 12 | pages=  | pmid=25786843 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25786843  }} </ref>
* Although uncommon, hepatic adenomas do rarely degenerate into hepatocellular carcinomas (HCC).<ref name=a>{{cite web | title = Radiopedia 2015 Hepatic adenoma [Dr Matt A. Morgan and Dr Koshy Jacob]| url = http://radiopaedia.org/articles/hepatic-adenoma }}</ref> The risk factor for malignant transformation of hepatic adenoma to hepatocellular carcinoma is:<ref name="pmid25786843">{{cite journal| author=Aamann L, Schultz N, Fallentin E, Hamilton-Dutoit S, Vogel I, Grønbæk H| title=[Hepatocellular adenoma - new classification and recommendations]. | journal=Ugeskr Laeger | year= 2015 | volume= 177 | issue= 12 | pages=  | pmid=25786843 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25786843  }} </ref>

Revision as of 14:45, 16 October 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]

Overview

If left untreated, 30% of patients with hepatocellular adenoma may progress to develop risk of bleeding.[1]Common complication of Hepatocellular adenoma includes spontaneous rupture, haemorrhage[2][3]and malignant transformation to Hepatocellular carcinoma.[3]

Hepatocellular adenoma natural history

If left untreated, 30% of patients with hepatocellular adenoma may progress to develop risk of bleeding.[4]

Complications

Common complication of hepatocellular adenoma include:

  • Spontaneous rupture and subsequently haemorrhage[2][3]
  • Although uncommon, hepatic adenomas do rarely degenerate into hepatocellular carcinomas (HCC).[2] The risk factor for malignant transformation of hepatic adenoma to hepatocellular carcinoma is:[3]
  • Gender (men)
  • Size (> 8 cm)
  • Subtype of hepatocellular adenoma

Prognosis

References

  1. ↑ Hepatocellular adenoma.Wikipedia 2015. https://en.wikipedia.org/wiki/Hepatocellular_adenoma Accessed on October 16, 2015
  2. ↑ 2.0 2.1 2.2 "Radiopedia 2015 Hepatic adenoma [Dr Matt A. Morgan and Dr Koshy Jacob]".
  3. ↑ 3.0 3.1 3.2 3.3 Aamann L, Schultz N, Fallentin E, Hamilton-Dutoit S, Vogel I, Grønbæk H (2015). "[Hepatocellular adenoma - new classification and recommendations]". Ugeskr Laeger. 177 (12). PMID 25786843.
  4. ↑ Hepatocellular adenoma.Wikipedia 2015. https://en.wikipedia.org/wiki/Hepatocellular_adenoma Accessed on October 16, 2015


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