Gestational trophoblastic neoplasia laboratory findings: Difference between revisions
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===Quantitative serum HCG=== | ===Quantitative serum HCG=== | ||
* [[Human chorionic gonadotropin]] (HCG or b-HCG) is the most common tumour marker test used to diagnose GTD. | * [[Human chorionic gonadotropin]] (HCG or b-HCG) is the most common tumour marker test used to diagnose GTD. | ||
* HCG is a very sensitive test for diagnosing most gestational trophoblastic tumours. HCG is usually measured in the blood, but it can also be measured in the urine. | * HCG is a very sensitive test for diagnosing most gestational trophoblastic tumours. HCG is usually measured in the blood, but it can also be measured in the urine. | ||
* HCG levels are much higher in women with complete [[hydatidiform mole]]s and gestational choriocarcinoma compared to HCG levels in women with a normal pregnancy. | * HCG levels are much higher in women with complete [[hydatidiform mole]]s and gestational choriocarcinoma compared to HCG levels in women with a normal pregnancy. | ||
* With partial moles, the HCG level is higher than normal, but it is not as high as with other types of GTD. | * With partial moles, the HCG level is higher than normal, but it is not as high as with other types of GTD. | ||
* With placental site tumours, the HCG level may be slightly higher than normal, but it is not considered a good marker for this type of tumour. | * With placental site tumours, the HCG level may be slightly higher than normal, but it is not considered a good marker for this type of tumour. | ||
* An HCG test can help find GTD after pregnancy or miscarriage as this hormone should not be present in the blood or urine soon afterward. | * An HCG test can help find GTD after pregnancy or miscarriage as this hormone should not be present in the blood or urine soon afterward. | ||
===Human placental lactogen (hPL)=== | ===Human placental lactogen (hPL)=== | ||
* Human placental lactogen (hPL) is a tumour marker that may be used to follow women with placental site trophoblastic tumours. High hPL levels are found in women with some types of GTD. | * Human placental lactogen (hPL) is a tumour marker that may be used to follow women with placental site trophoblastic tumours. High hPL levels are found in women with some types of GTD. | ||
Revision as of 15:24, 13 October 2015
Overview
Increased quantitative beta HCG levels.
Laboratory Findings
Blood tests that may be done include:
Quantitative serum HCG
- Human chorionic gonadotropin (HCG or b-HCG) is the most common tumour marker test used to diagnose GTD.
- HCG is a very sensitive test for diagnosing most gestational trophoblastic tumours. HCG is usually measured in the blood, but it can also be measured in the urine.
- HCG levels are much higher in women with complete hydatidiform moles and gestational choriocarcinoma compared to HCG levels in women with a normal pregnancy.
- With partial moles, the HCG level is higher than normal, but it is not as high as with other types of GTD.
- With placental site tumours, the HCG level may be slightly higher than normal, but it is not considered a good marker for this type of tumour.
- An HCG test can help find GTD after pregnancy or miscarriage as this hormone should not be present in the blood or urine soon afterward.
Human placental lactogen (hPL)
- Human placental lactogen (hPL) is a tumour marker that may be used to follow women with placental site trophoblastic tumours. High hPL levels are found in women with some types of GTD.
Complete blood count
- Complete blood count can check for anemia from long-term (chronic) vaginal bleeding.