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{{Thymoma}}
{{Thymoma}}
{{CMG}} {{AE}} {{AM}} {{AAM}}
{{CMG}} {{AE}} {{AM}} {{AAM}}
==Overview==
Thymoma must be differentiated from other diseases such as [[thymic carcinoma]], thymic [[cyst]], thymic [[hyperplasia]] and [[germ cell tumors]].


==Differential Diagnosis==
==Differential Diagnosis==

Revision as of 17:56, 23 September 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Amr Marawan, M.D. [2] Ahmad Al Maradni, M.D. [3]

Overview

Thymoma must be differentiated from other diseases such as thymic carcinoma, thymic cyst, thymic hyperplasia and germ cell tumors.

Differential Diagnosis

Differential diagnosis of thymomas types A, AB, B and thymic carcinomas.[1]

Thymoma must be differentiated from other diseases such as:

  • Thymic masses
  • Thymic Cyst: It is incidental mass that may be congenital or acquired. It might contain parathyroid or salivary tissue, as they has a common embryological origin.
  • Thymic hyperplasia: Resected only if associated paraneoplastic syndrome.
  • Thymolipoma: Increased thymic size with mixed adipose tissue.
  • Thymic carcinoma: Rare thymic tumor, poor survival rate, high rate of recurrence. Sometimes called type C thymoma.
  • Thymic carcinoid: Also called thymic neuroendocrine tumors, uncommon and present as a mass in the anterior mediastinum.
  • Ectopic parathyroid tissue.
  • Germ cell tumors
  • The most common site of extragonadal germ cell tumors is the mediastinum.
  • Teratomas: Represents two thirds of mediastinal germ cell tumor. Usually benign, but when malignant, it's very aggressive and very poor prognosis.
  • Dermoid cysts: Very rare tumor, only 118 cases have been reported.[2]
  • Malignant germ cell tumor: 90% of malignant mediastinal germ cell tumor occur in males. Full physical examination and scrotal ultrasound is required.
  • Seminomas: Slightly more common, grow slowly but might reach large sizes.
  • Non-seminomatous germ cell tumor: Consists of yolk sac tumor, embryonal cell carcinoma, and/or choriocarcinoma. Commonly between 20-40 years of age.
  • Lymphoma (terrible, could be middle or posterior mediastinal too)

References

  1. "http://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb10/BB10.pdf" (PDF). External link in |title= (help)
  2. Ripa, LW. (1992). "Rinses for the control of dental caries". Int Dent J. 42 (4 Suppl 1): 263–9. PMID 1399044. Unknown parameter |month= ignored (help)

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