21-hydroxylase deficiency natural history, complications and prognosis: Difference between revisions
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* When a person is well, missing a dose, or even several doses, may produce little in the way of immediate symptoms. However, glucocorticoid needs are increased during illness and stress. | * When a person is well, missing a dose, or even several doses, may produce little in the way of immediate symptoms. However, glucocorticoid needs are increased during illness and stress. | ||
* Missed doses during time of illness can lead within hours to [[hypotension]], [[Shock (medical)|shock]], and death. | * Missed doses during time of illness can lead within hours to [[hypotension]], [[Shock (medical)|shock]], and death. | ||
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{{Reflist|2}} | {{Reflist|2}} | ||
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Revision as of 14:19, 21 September 2015
Congenital adrenal hyperplasia due to 21-hydroxylase deficiency Microchapters |
Differentiating Congenital adrenal hyperplasia due to 21-hydroxylase deficiency from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]
Overview
The prognosis of congenital adrenal hyperplasia due to 21-hydroxylase deficiency is generally good with treatment. Common complications of 21-hydroxylase deficient congenital adrenal hyperplasia include short stature, adrenal crisis, infertility, and precocious puberty.
Complications
Complications associated with 21-hydroxylase deficient congenital adrenal hyperplasia include:
Prognosis
- A small percentage of children and adults with infancy or childhood onset congenital adrenal hyperplasia die of adrenal crisis. Even after diagnosis and initiation of treatment.
- Deaths from this are entirely avoidable if the child and his family understand that the daily glucocorticoids must not allow to be interrupted by an illness.
- When a person is well, missing a dose, or even several doses, may produce little in the way of immediate symptoms. However, glucocorticoid needs are increased during illness and stress.
- Missed doses during time of illness can lead within hours to hypotension, shock, and death.